Protein: XIAP
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)

Gene: XIAP
Organism: Mus musculus
Interactions: 17
UniProt ID: Q60989

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1222124

DBLOH
Diablo IAP-binding mitochondrial protein

3

11

Small-scale

0.827

High

1222121

TGFR1
TGF-beta receptor type-1

1

6

Small-scale

0.665

High

1022006

CASP7
Caspase-7

1

20

Small-scale

0.621

High

1000543

CASP3
Caspase-3

1

20

Small-scale

0.618

High

1222125

HTRA2
Serine protease HTRA2, mitochondrial

2

15

Small-scale

0.595

High

1222120

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.590

High

509093

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

15

High-throughput

0.579

High

147798

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.561

High

109297

G5E8L8
mitogen-activated protein kinase kinase kinase

1

8

Small-scale

0.553

High

1222126

MAGD1
Melanoma-associated antigen D1

1

5

Small-scale

0.501

High

922802

CCHL
Holocytochrome c-type synthase

1

2

Small-scale

0.488

High

704310

SEPT4
Septin-4

1

6

Small-scale

0.479

High

988890

RAC1
Ras-related C3 botulinum toxin substrate 1

1

11

Small-scale

0.479

High

1032081

NOTC1
Neurogenic locus notch homolog protein 1

1

15

Small-scale

0.479

High

1188180

STING
Stimulator of interferon genes protein

1

4

High-throughput

0.479

High

1222122

NEB2
Neurabin-2

1

4

High-throughput

0.479

High

1222123

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

14

Small-scale

0.479

High


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Last updated: 11Aug2025