Protein: UBC9
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)

Gene: UBC9
Organism: Saccharomyces cerevisiae S288C
Interactions: 148
UniProt ID: P50623

Gene Ontology (top 5):
GO:0000022 - mitotic spindle elongation
GO:0000794 - condensed nuclear chromosome
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0016925 - protein sumoylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

841429

SIZ1
E3 SUMO-protein ligase SIZ1

12

14

Small-scale

0.981

High

841451

SIZ2
E3 SUMO-protein ligase SIZ2

11

14

Small-scale

0.976

High

841454

SMT3
Ubiquitin-like protein SMT3

10

18

Small-scale

0.972

High

841408

UBA2
Ubiquitin-activating enzyme E1-like

6

20

Small-scale

0.950

High

550565

PCNA
Proliferating cell nuclear antigen

5

8

Small-scale

0.912

High

500613

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

3

20

Small-scale

0.863

High

841407

UBC9
SUMO-conjugating enzyme UBC9

3

16

Small-scale

0.847

High

841442

RHC31
DNA damage tolerance protein RHC31

3

20

Small-scale

0.845

High

841441

ESC2
Protein ESC2

3

0

Small-scale

0.806

High

751448

NSE2
E3 SUMO-protein ligase MMS21

8

0

Small-scale

0.716

High

699161

RAD5
DNA repair protein RAD5

1

12

Small-scale

0.713

High

715647

SGS1
ATP-dependent helicase SGS1

4

3

Small-scale

0.676

High

608711

UBA1
Ubiquitin-activating enzyme E1 1

1

20

Small-scale

0.647

High

841409

IMB5
Importin subunit beta-5

1

7

Small-scale

0.647

High

523420

SRS2
ATP-dependent DNA helicase SRS2

2

3

Small-scale

0.622

High

410231

UBC2
Ubiquitin-conjugating enzyme E2 2

1

15

Small-scale

0.621

High

765472

LIS1
Nuclear distribution protein PAC1

1

10

Small-scale

0.621

High

767865

SLX8
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8

1

2

Small-scale

0.621

High

548547

GCN2
eIF-2-alpha kinase GCN2

1

5

High-throughput

0.618

High

744651

TAF5
Transcription initiation factor TFIID subunit 5

1

11

High-throughput

0.618

High

841428

SXM1
Importin beta SMX1

1

6

High-throughput

0.618

High

841433

ERB1
Ribosome biogenesis protein ERB1

1

6

High-throughput

0.618

High

841443

YL419
Putative ATP-dependent RNA helicase YLR419W

1

3

High-throughput

0.618

High

419626

RAD52
DNA repair and recombination protein RAD52

2

3

Small-scale

0.594

High

841424

NSE5
Non-structural maintenance of chromosome element 5

2

0

Small-scale

0.587

High

698597

MRE11
Double-strand break repair protein MRE11

2

2

Small-scale

0.584

High

841430

EUC1
Transcription factor-like protein EUC1

2

0

Small-scale

0.561

High

810699

NET1
Nucleolar protein NET1

1

1

High-throughput

0.561

High

691914

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

2

0

Small-scale

0.559

High

805150

STU2
Protein STU2

2

1

Small-scale

0.556

High

768915

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

690327

CDC11
Cell division control protein 11

2

6

Small-scale

0.549

High

690235

CDC3
Cell division control protein 3

2

5

Small-scale

0.543

High

514576

BIK1
Nuclear fusion protein BIK1

1

2

Small-scale

0.527

High

692461

KAR9
Karyogamy protein KAR9

1

1

Small-scale

0.527

High

841419

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.512

High

586426

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.508

High

632580

RAD51
DNA repair protein RAD51

1

5

High-throughput

0.508

High

697593

KA122
Importin beta-like protein KAP122

1

0

Small-scale

0.504

High

841437

CST9
Chromosome stability protein 9

1

0

Small-scale

0.504

High

675759

RENT1
ATP-dependent helicase NAM7

1

1

Small-scale

0.501

High

746201

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

3

Small-scale

0.501

High

767108

YEN1
Holliday junction resolvase YEN1

1

2

Small-scale

0.501

High

841417

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.501

High

841452

RAD59
DNA repair protein RAD59

1

3

Small-scale

0.501

High

536256

RED1
Protein RED1

1

0

Small-scale

0.486

High

778653

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

Small-scale

0.486

High

691645

NUP2
Nucleoporin NUP2

1

5

Small-scale

0.481

High

698557

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

2

Small-scale

0.481

High

766761

BIM1
Protein BIM1

1

2

Small-scale

0.481

High

774055

NDC80
Kinetochore protein NDC80

1

2

High-throughput

0.481

High

841446

SLK19
Kinetochore protein SLK19

1

4

High-throughput

0.481

High

778562

MSH4
MutS protein homolog 4

1

0

Small-scale

0.480

High

420146

TOP2
DNA topoisomerase 2

1

2

High-throughput

0.479

High

520626

YPK1
Serine/threonine-protein kinase YPK1

1

2

High-throughput

0.479

High

578549

SEC18
Vesicular-fusion protein SEC18

1

3

High-throughput

0.479

High

593772

DBP5
ATP-dependent RNA helicase DBP5

1

3

High-throughput

0.479

High

604586

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.479

High

605087

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

636159

NOT1
General negative regulator of transcription subunit 1

1

1

High-throughput

0.479

High

696230

STH1
Nuclear protein STH1/NPS1

1

3

High-throughput

0.479

High

699701

DRS1
ATP-dependent RNA helicase DRS1

1

3

High-throughput

0.479

High

742032

NOP4
Nucleolar protein 4

1

1

High-throughput

0.479

High

752159

KSP1
Serine/threonine-protein kinase KSP1

1

5

High-throughput

0.479

High

757212

SPP41
Protein SPP41

1

5

High-throughput

0.479

High

765584

SAP1
Protein SAP1

1

4

High-throughput

0.479

High

766662

NUG1
Nuclear GTP-binding protein NUG1

1

1

High-throughput

0.479

High

778817

NOP2
25S rRNA

1

1

High-throughput

0.479

High

799832

ROK1
ATP-dependent RNA helicase ROK1

1

2

High-throughput

0.479

High

841412

NOP13
Nucleolar protein 13

1

3

High-throughput

0.479

High

841414

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

841415

EF3B
Elongation factor 3B

1

1

High-throughput

0.479

High

841423

HAS1
ATP-dependent RNA helicase HAS1

1

2

High-throughput

0.479

High

841425

TAF12
Transcription initiation factor TFIID subunit 12

1

1

High-throughput

0.479

High

841426

HMO1
High mobility group protein 1

1

9

High-throughput

0.479

High

841436

ARP9
Actin-like protein ARP9

1

3

High-throughput

0.479

High

841439

FKBP4
FK506-binding protein 4

1

1

High-throughput

0.479

High

841444

TSR1
Ribosome biogenesis protein TSR1

1

3

High-throughput

0.479

High

841455

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.479

High

732499

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

812267

BIR1
Protein BIR1

1

0

High-throughput

0.460

High

841431

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.460

High

141683

YH11B
Transposon Ty1-H Gag-Pol polyprotein

1

0

High-throughput

0.458

High

429739

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.458

High

450476

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

630423

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.458

High

679794

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.458

High

688091

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.458

High

689757

SFP1
Transcription factor SFP1

1

0

High-throughput

0.458

High

702688

TYE7
Transcription factor TYE7

1

0

High-throughput

0.458

High

733190

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.458

High

742667

AAP1
Alanine/arginine aminopeptidase

1

0

High-throughput

0.458

High

751279

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.458

High

755838

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

757181

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.458

High

764203

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.458

High

793564

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

0

High-throughput

0.458

High

841411

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

841421

RLI1
Translation initiation factor RLI1

1

0

High-throughput

0.458

High

841422

VPS72
Vacuolar protein sorting-associated protein 72

1

0

High-throughput

0.458

High

841427

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.458

High

841438

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

841440

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

841448

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.458

High

491816

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

511981

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

695085

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

759195

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.438

High

343134

THDH
Threonine dehydratase, mitochondrial

1

3

High-throughput

0.437

High

551379

ABP1
Actin-binding protein

1

1

High-throughput

0.437

High

629576

CDC10
Cell division control protein 10

1

6

High-throughput

0.437

High

630641

TRX3
Thioredoxin-3, mitochondrial

1

2

High-throughput

0.437

High

688043

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

1

High-throughput

0.437

High

690550

CDC12
Cell division control protein 12

1

5

High-throughput

0.437

High

691566

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.437

High

731063

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.437

High

747014

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

3

High-throughput

0.437

High

750068

TSL1
Trehalose synthase complex regulatory subunit TSL1

1

1

High-throughput

0.437

High

765140

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

4

High-throughput

0.437

High

770491

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

1

High-throughput

0.437

High

798100

COPD
Coatomer subunit delta

1

1

High-throughput

0.437

High

841410

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

1

1

High-throughput

0.437

High

841416

DNM1
Dynamin-related protein DNM1

1

2

High-throughput

0.437

High

841418

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

1

High-throughput

0.437

High

841420

NOG1
Nucleolar GTP-binding protein 1

1

10

High-throughput

0.437

High

841434

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.437

High

841445

NOP12
Nucleolar protein 12

1

2

High-throughput

0.437

High

841447

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.437

High

841450

LEU9
2-isopropylmalate synthase 2, mitochondrial

1

1

High-throughput

0.437

High

841413

INN1
Ingression protein 1

1

0

Small-scale

0.282

High

767007

FIR1
Factor interacting with REF2

1

0

Small-scale

0.251

Low

404076

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.249

Low

427379

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

0

High-throughput

0.249

Low

627543

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.249

Low

634036

BUD3
Bud site selection protein 3

1

0

High-throughput

0.249

Low

668083

TRXB1
Thioredoxin reductase 1

1

0

High-throughput

0.249

Low

733873

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.249

Low

746660

CST26
2-acyl-1-lysophosphatidylinositol acyltransferase

1

0

High-throughput

0.249

Low

752018

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.249

Low

752047

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

762101

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.249

Low

765642

BEM2
GTPase-activating protein BEM2/IPL2

1

0

High-throughput

0.249

Low

792503

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

841432

TMA64
Translation machinery-associated protein 64

1

0

High-throughput

0.249

Low

841435

CYK2
Cytokinesis protein 2

1

0

High-throughput

0.249

Low

841449

MRH1
Protein MRH1

1

0

High-throughput

0.249

Low

841453

RDL1
Thiosulfate:glutathione sulfurtransferase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024