Protein: PSA1
Proteasome subunit alpha type-1 (Macropain subunit C7-alpha) (Multicatalytic endopeptidase complex C7) (Proteasome component C7-alpha) (Proteasome component Y8) (Proteinase YSCE subunit 7) (SCL1 suppressor protein)

Gene: PSA1, SCL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: P21243

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

597282

PSB4
Proteasome subunit beta type-4

13

20

Small-scale

0.979

High

597194

PSA7
Probable proteasome subunit alpha type-7

11

20

Small-scale

0.978

High

597286

PSA2
Proteasome subunit alpha type-2

9

18

Small-scale

0.972

High

597296

PSB5
Proteasome subunit beta type-5

7

20

Small-scale

0.962

High

597328

PSA4
Proteasome subunit alpha type-4

7

20

Small-scale

0.962

High

597327

PSA6
Proteasome subunit alpha type-6

6

20

Small-scale

0.943

High

597313

UMP1
Proteasome maturation factor UMP1

6

1

Small-scale

0.941

High

597285

PSA3
Proteasome subunit alpha type-3

5

20

Small-scale

0.922

High

597290

PSB3
Proteasome subunit beta type-3

4

20

High-throughput

0.896

High

597297

PSB7
Proteasome subunit beta type-7

4

20

High-throughput

0.896

High

597315

PSB1
Proteasome subunit beta type-1

4

20

High-throughput

0.896

High

597331

BLM10
Proteasome activator BLM10

4

7

Small-scale

0.890

High

597287

PSB6
Proteasome subunit beta type-6

3

20

High-throughput

0.839

High

597304

PRS6A
26S proteasome regulatory subunit 6A

3

20

Small-scale

0.827

High

597288

PSB2
Proteasome subunit beta type-2

2

20

High-throughput

0.776

High

597299

PSA5
Proteasome subunit alpha type-5

2

19

High-throughput

0.776

High

597306

PRS7
26S proteasome regulatory subunit 7 homolog

2

20

Small-scale

0.754

High

597332

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

10

20

Small-scale

0.751

High

597354

RPN5
26S proteasome regulatory subunit RPN5

4

19

Small-scale

0.691

High

597353

POC4
Proteasome chaperone 4

1

1

Small-scale

0.665

High

597321

RPN10
26S proteasome regulatory subunit RPN10

3

10

High-throughput

0.662

High

597302

RPN2
26S proteasome regulatory subunit RPN2

3

20

Small-scale

0.660

High

597298

IMB3
Importin subunit beta-3

2

1

High-throughput

0.621

High

597281

PSA1
Proteasome subunit alpha type-1

1

19

High-throughput

0.618

High

597305

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

597309

POC2
Proteasome assembly chaperone 2

1

1

High-throughput

0.618

High

597329

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

597336

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

597340

PRS8
26S proteasome regulatory subunit 8 homolog

1

20

High-throughput

0.618

High

597356

RPN6
26S proteasome regulatory subunit RPN6

1

20

High-throughput

0.618

High

597289

SIS1
Protein SIS1

2

6

High-throughput

0.601

High

597349

POC3
Proteasome chaperone 3

1

0

Small-scale

0.586

High

597316

ECM29
Proteasome component ECM29

2

8

High-throughput

0.584

High

597317

RPN1
26S proteasome regulatory subunit RPN1

2

20

Small-scale

0.584

High

581334

MED14
Mediator of RNA polymerase II transcription subunit 14

2

0

High-throughput

0.563

High

597345

POC1
Proteasome chaperone 1

1

1

High-throughput

0.553

High

597326

SSB2
Ribosome-associated molecular chaperone SSB2

2

10

High-throughput

0.552

High

597291

PWP2
Periodic tryptophan protein 2

2

2

High-throughput

0.537

High

597284

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

1

High-throughput

0.515

High

597318

CIC1
Proteasome-interacting protein CIC1

1

0

Small-scale

0.513

High

597308

NOT4
General negative regulator of transcription subunit 4

1

2

High-throughput

0.501

High

397572

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.493

High

597310

YK50
Mitochondrial hydrolase YKR070W

1

0

High-throughput

0.493

High

597343

URH1
Uridine nucleosidase

1

0

High-throughput

0.493

High

597352

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.493

High

141824

RPN13
26S proteasome regulatory subunit RPN13

1

1

High-throughput

0.479

High

549024

TRM1
tRNA

1

1

High-throughput

0.479

High

566125

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

587925

HSP60
Heat shock protein 60, mitochondrial

1

6

Small-scale

0.479

High

597294

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

597295

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

597301

RPN12
26S proteasome regulatory subunit RPN12

1

3

High-throughput

0.479

High

597303

RAD23
UV excision repair protein RAD23

1

20

High-throughput

0.479

High

597314

HSM3
DNA mismatch repair protein HSM3

1

1

Small-scale

0.479

High

597319

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

1

High-throughput

0.479

High

597324

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

597325

RPN3
26S proteasome regulatory subunit RPN3

1

7

High-throughput

0.479

High

597330

MLP2
Protein MLP2

1

1

High-throughput

0.479

High

597333

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

12

High-throughput

0.479

High

597338

APJ1
J domain-containing protein APJ1

1

7

High-throughput

0.479

High

597341

TOM1
E3 ubiquitin-protein ligase TOM1

1

11

High-throughput

0.479

High

597342

RPN9
26S proteasome regulatory subunit RPN9

1

10

High-throughput

0.479

High

597347

RPN7
26S proteasome regulatory subunit RPN7

1

20

High-throughput

0.479

High

597351

RPN8
26S proteasome regulatory subunit RPN8

1

14

High-throughput

0.479

High

597312

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.470

High

294092

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.458

High

411162

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.458

High

479226

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.458

High

597307

MTR2
mRNA transport regulator MTR2

1

0

High-throughput

0.458

High

597320

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

597337

CAF40
Protein CAF40

1

0

High-throughput

0.458

High

597344

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

597355

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.458

High

365781

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.445

High

490323

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

597292

FUB1
Silencing boundary-establishment protein FUB1

1

1

High-throughput

0.437

High

597293

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

597311

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

597322

DHH1
ATP-dependent RNA helicase DHH1

1

4

High-throughput

0.437

High

597323

ATC3
Phospholipid-transporting ATPase DRS2

1

3

High-throughput

0.437

High

597348

UTP4
U3 small nucleolar RNA-associated protein 4

1

4

High-throughput

0.437

High

597283

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.426

High

434789

AMYG
Glucoamylase, intracellular sporulation-specific

1

0

High-throughput

0.269

Low

560899

EF3A
Elongation factor 3A

1

0

High-throughput

0.269

Low

597300

DCG1
Protein DCG1

1

0

High-throughput

0.269

Low

597334

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.269

Low

597346

ATG38
Autophagy-related protein 38

1

0

High-throughput

0.269

Low

597335

USE1
Protein transport protein USE1

1

0

High-throughput

0.249

Low

597339

DDR2
Protein DDR2

1

0

High-throughput

0.249

Low

597350

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024