Protein: UTP6
U3 small nucleolar RNA-associated protein 6 (U3 snoRNA-associated protein 6) (U three protein 6)

Gene: UTP6
Organism: Saccharomyces cerevisiae S288C
Interactions: 152
UniProt ID: Q02354

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

970467

UTP21
U3 small nucleolar RNA-associated protein 21

10

5

Small-scale

0.758

High

635628

PWP2
Periodic tryptophan protein 2

9

2

Small-scale

0.754

High

970466

UTP13
U3 small nucleolar RNA-associated protein 13

7

4

Small-scale

0.751

High

772663

UTP18
U3 small nucleolar RNA-associated protein 18

11

0

Small-scale

0.727

High

970459

DHR1
Probable ATP-dependent RNA helicase DHR1

6

5

Small-scale

0.727

High

970489

UTP12
U3 small nucleolar RNA-associated protein 12

5

2

Small-scale

0.720

High

970474

NOC4
Nucleolar complex protein 4

9

0

Small-scale

0.720

High

748682

ENP1
Essential nuclear protein 1

8

0

Small-scale

0.715

High

970493

NOP58
Nucleolar protein 58

5

1

Small-scale

0.714

High

634738

KRR1
KRR1 small subunit processome component

6

0

High-throughput

0.705

High

811543

MPP10
U3 small nucleolar RNA-associated protein MPP10

5

0

Small-scale

0.698

High

767402

UTP7
U3 small nucleolar RNA-associated protein 7

4

2

High-throughput

0.697

High

970476

UTP4
U3 small nucleolar RNA-associated protein 4

4

2

Small-scale

0.694

High

970455

UTP6
U3 small nucleolar RNA-associated protein 6

4

1

Small-scale

0.693

High

860721

UTP22
U3 small nucleolar RNA-associated protein 22

5

0

High-throughput

0.691

High

792550

UTP10
U3 small nucleolar RNA-associated protein 10

5

0

High-throughput

0.684

High

700089

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

3

1

High-throughput

0.667

High

707126

DCA13
Protein SOF1

3

3

High-throughput

0.667

High

970456

UTP17
NET1-associated nuclear protein 1

3

3

High-throughput

0.667

High

970460

UTP15
U3 small nucleolar RNA-associated protein 15

3

2

High-throughput

0.667

High

970463

RRP5
rRNA biogenesis protein RRP5

3

3

High-throughput

0.667

High

970473

RRP9
Ribosomal RNA-processing protein 9

3

3

High-throughput

0.667

High

866033

NAT10
RNA cytidine acetyltransferase

4

0

High-throughput

0.657

High

970486

SAS10
Something about silencing protein 10

3

0

Small-scale

0.649

High

706440

RS3A1
Small ribosomal subunit protein eS1A

3

0

High-throughput

0.638

High

715969

UTP20
U3 small nucleolar RNA-associated protein 20

3

0

High-throughput

0.638

High

756774

UTP9
U3 small nucleolar RNA-associated protein 9

3

0

High-throughput

0.638

High

970471

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

3

0

High-throughput

0.638

High

970462

UTP14
U3 small nucleolar RNA-associated protein 14

3

0

High-throughput

0.630

High

970484

BMS1
Ribosome biogenesis protein BMS1

3

0

High-throughput

0.630

High

799844

ROK1
ATP-dependent RNA helicase ROK1

3

0

High-throughput

0.628

High

816892

NOL10
Ribosome biogenesis protein ENP2

3

0

High-throughput

0.628

High

970469

SGD1
Suppressor of glycerol defect protein 1

2

1

High-throughput

0.614

High

480831

RS8A
Small ribosomal subunit protein eS8A

3

0

High-throughput

0.613

High

861013

UTP8
U3 small nucleolar RNA-associated protein 8

3

0

Small-scale

0.613

High

768103

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

0

High-throughput

0.588

High

864720

ESF2
Pre-rRNA-processing protein ESF2

2

0

High-throughput

0.588

High

970472

ESF1
Pre-rRNA-processing protein ESF1

2

0

High-throughput

0.588

High

970492

RRP36
rRNA biogenesis protein RRP36

2

0

High-throughput

0.588

High

970497

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.588

High

769231

SSB2
Ribosome-associated molecular chaperone SSB2

3

3

High-throughput

0.587

High

970468

MRD1
Multiple RNA-binding domain-containing protein 1

2

0

Small-scale

0.585

High

810900

MTR4
ATP-dependent RNA helicase DOB1

2

4

Small-scale

0.584

High

399602

RLA0
Large ribosomal subunit protein uL10

2

0

High-throughput

0.576

High

549472

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

High-throughput

0.576

High

733907

RPF2
Ribosome biogenesis protein RPF2

2

0

High-throughput

0.576

High

865409

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

730722

DHR2
Probable ATP-dependent RNA helicase DHR2

1

7

High-throughput

0.541

High

471208

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.533

High

798377

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.518

High

860529

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

865561

SQS1
Protein SQS1

1

0

High-throughput

0.518

High

492170

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.504

High

710092

TFC3
Transcription factor tau 138 kDa subunit

1

0

High-throughput

0.493

High

676298

XPO1
Exportin-1

1

1

High-throughput

0.489

High

141478

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

753171

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.479

High

809576

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

860798

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

865608

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.479

High

970458

UTP5
U3 small nucleolar RNA-associated protein 5

1

3

High-throughput

0.479

High

970465

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

970475

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

970490

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

970491

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

450157

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.470

High

837169

HSV2
SVP1-like protein 2

1

2

High-throughput

0.470

High

407258

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408072

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413665

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

480266

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

482411

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

593685

DBP4
ATP-dependent RNA helicase HCA4

1

0

High-throughput

0.458

High

630243

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

630526

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

632040

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

645603

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

700580

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

711063

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

730074

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

733590

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.458

High

752617

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

754985

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.458

High

755190

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

758455

RRP8
25S rRNA

1

0

High-throughput

0.458

High

774269

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

774739

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

775379

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

811338

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

816963

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

819875

TRF5
Poly(A) RNA polymerase protein 1

1

0

Small-scale

0.458

High

861600

PXR1
Protein PXR1

1

0

Small-scale

0.458

High

866603

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

970457

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

970464

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

970477

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

970478

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

970479

RRP44
Exosome complex exonuclease DIS3

1

0

High-throughput

0.458

High

970480

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

970482

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

970485

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

970487

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

970494

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

970495

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

970498

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

605578

DBF2
Cell cycle protein kinase DBF2

1

2

High-throughput

0.437

High

693149

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

1

High-throughput

0.437

High

742947

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.437

High

866656

ARP5
Actin-related protein 5

1

1

High-throughput

0.437

High

967707

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

970496

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

499045

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.407

High

512402

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.407

High

750143

IF5
Eukaryotic translation initiation factor 5

2

0

High-throughput

0.307

High

704558

PPZ2
Serine/threonine-protein phosphatase PP-Z2

1

0

High-throughput

0.269

Low

764118

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.269

Low

809630

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.269

Low

970488

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.269

Low

358216

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383307

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

404677

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

405784

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

426106

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

472354

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

524423

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

645264

RL16B
Large ribosomal subunit protein uL13B

1

0

High-throughput

0.249

Low

649921

CDC15
Cell division control protein 15

1

0

High-throughput

0.249

Low

665006

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

755111

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.249

Low

758696

TEM1
Protein TEM1

1

0

High-throughput

0.249

Low

762486

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

775235

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

820122

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

860352

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

866415

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

970470

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

970481

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

970483

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

732171

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.238

Low

778694

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.238

Low

340248

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

366759

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.232

Low

368334

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

498579

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.232

Low

540144

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

556243

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

766539

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

773730

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low

784205

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.232

Low

785173

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

970461

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024