Protein: TLE1
Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg-1)

Gene: TLE1
Organism: Mus musculus
Interactions: 18
UniProt ID: Q62440

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1224201

TLE1
Transducin-like enhancer protein 1

2

17

Small-scale

0.757

High

1222429

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

Small-scale

0.691

High

988924

TLE5
TLE family member 5

1

17

Small-scale

0.618

High

1224204

FNDC5
Fibronectin type III domain-containing protein 5

1

3

High-throughput

0.553

High

1224205

HES6
Transcription cofactor HES-6

1

20

High-throughput

0.541

High

991151

HMGB1
High mobility group protein B1

1

20

Small-scale

0.536

High

148702

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.536

High

599654

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

11

Small-scale

0.536

High

1224203

SKOR1
SKI family transcriptional corepressor 1

1

6

Small-scale

0.515

High

1064913

RUNX2
Runt-related transcription factor 2

1

11

Small-scale

0.501

High

148081

BARX2
Homeobox protein BarH-like 2

1

20

Small-scale

0.479

High

916137

LBX1
Transcription factor LBX1

1

20

Small-scale

0.479

High

1222115

FOXG1
Forkhead box protein G1

1

20

Small-scale

0.479

High

1223976

SSXT
Protein SSXT

1

10

Small-scale

0.479

High

1224202

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.479

High

1224206

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

4

Small-scale

0.479

High

398487

CFAD
Complement factor D

1

8

High-throughput

0.437

High


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Last updated: 11Aug2025