Protein: CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC 2.7.11.21)

Gene: CDC5
Organism: Saccharomyces cerevisiae S288C
Interactions: 142
UniProt ID: P32562

Gene Ontology (top 5):
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

693089

SWE1
Mitosis inhibitor protein kinase SWE1

6

19

Small-scale

0.945

High

687524

DBF4
DDK kinase regulatory subunit DBF4

7

0

Small-scale

0.923

High

605954

RAD53
Serine/threonine-protein kinase RAD53

4

18

Small-scale

0.912

High

693145

CDC14
Tyrosine-protein phosphatase CDC14

3

8

Small-scale

0.870

High

339519

CDK1
Cyclin-dependent kinase 1

3

3

Small-scale

0.858

High

412539

CDC7
Cell division control protein 7

3

17

Small-scale

0.855

High

687865

NUD1
Protein NUD1

3

4

Small-scale

0.845

High

693083

IME2
Meiosis induction protein kinase IME2/SME1

2

17

Small-scale

0.789

High

620007

MPIP
M-phase inducer phosphatase

2

4

Small-scale

0.778

High

693126

FKH2
Fork head protein homolog 2

1

5

Small-scale

0.757

High

693179

SCC1
Sister chromatid cohesion protein 1

10

1

Small-scale

0.755

High

693135

BFA1
Mitotic check point protein BFA1

8

0

Small-scale

0.721

High

693114

MBO1
Gamma tubulin complex adapter SPC72

8

0

Small-scale

0.719

High

693130

SMC3
Structural maintenance of chromosomes protein 3

4

4

Small-scale

0.699

High

419835

SNF1
Carbon catabolite-derepressing protein kinase

1

17

Small-scale

0.691

High

693082

RPN2
26S proteasome regulatory subunit RPN2

1

1

Small-scale

0.691

High

693142

NOP13
Nucleolar protein 13

1

3

High-throughput

0.691

High

693146

NOP3
Serine/arginine

1

2

Small-scale

0.691

High

693087

SMC1
Structural maintenance of chromosomes protein 1

3

8

Small-scale

0.675

High

693101

MMS4
Crossover junction endonuclease MMS4

4

0

Small-scale

0.665

High

693154

MUS81
Crossover junction endonuclease MUS81

3

1

Small-scale

0.664

High

693098

CENPA
Histone H3-like centromeric protein CSE4

3

10

Small-scale

0.664

High

693134

MPS3
Spindle pole body assembly component MPS3

4

0

High-throughput

0.662

High

693103

MIP6
RNA-binding protein MIP6

1

0

Small-scale

0.656

High

693165

YP174
Nuclear envelope protein YPR174C

3

1

Small-scale

0.650

High

429184

SEC4
Ras-related protein SEC4

1

5

Small-scale

0.647

High

649872

CDC15
Cell division control protein 15

1

18

High-throughput

0.647

High

693081

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

17

High-throughput

0.647

High

693085

BEM3
GTPase-activating protein BEM3

1

6

Small-scale

0.647

High

693095

PP2C1
Protein phosphatase 2C homolog 1

1

14

High-throughput

0.647

High

693116

BEM2
GTPase-activating protein BEM2/IPL2

1

5

Small-scale

0.647

High

693176

CMR3
Zinc finger protein CRM3

1

3

High-throughput

0.647

High

693177

YP150
Putative serine/threonine-protein kinase YPL150W

1

19

High-throughput

0.647

High

693124

ULP2
Ubiquitin-like-specific protease 2

3

2

Small-scale

0.647

High

693180

REC8
Meiotic recombination protein REC8

3

0

Small-scale

0.642

High

693138

CDH1
APC/C activator protein CDH1

2

11

Small-scale

0.634

High

693125

SCC3
Cohesin subunit SCC3

2

1

High-throughput

0.628

High

693162

IMB1
Importin subunit beta-1

2

1

Small-scale

0.628

High

693131

IKS1
Probable serine/threonine-protein kinase IKS1

1

18

High-throughput

0.621

High

690298

CDC11
Cell division control protein 11

2

1

Small-scale

0.620

High

693140

CNM67
Chaotic nuclear migration protein 67

2

3

Small-scale

0.619

High

693112

TEM1
Protein TEM1

1

7

Small-scale

0.618

High

693117

BOI2
Protein BOI2

1

5

High-throughput

0.618

High

693144

MPS1
Serine/threonine-protein kinase MPS1

1

18

Small-scale

0.618

High

693170

SLK19
Kinetochore protein SLK19

2

9

Small-scale

0.611

High

693150

IMA1
Importin subunit alpha

2

0

Small-scale

0.602

High

619183

SPO13
Meiosis-specific protein SPO13

2

0

Small-scale

0.595

High

693129

NET1
Nucleolar protein NET1

2

1

Small-scale

0.595

High

693175

APC9
Anaphase-promoting complex subunit 9

2

0

Small-scale

0.592

High

693181

BBP1
Spindle pole component BBP1

2

0

Small-scale

0.588

High

624652

CG21
G2/mitotic-specific cyclin-1

1

0

Small-scale

0.586

High

365993

HSP82
ATP-dependent molecular chaperone HSP82

1

16

High-throughput

0.575

High

693115

EXO1
Exodeoxyribonuclease 1

1

2

High-throughput

0.573

High

693121

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.571

High

693171

NDD1
Nuclear division defective protein 1

1

0

Small-scale

0.545

High

693182

SFI1
Protein SFI1

1

0

Small-scale

0.537

High

454246

TBA1
Tubulin alpha-1 chain

1

7

Small-scale

0.536

High

522683

AAKG
5'-AMP-activated protein kinase subunit gamma

1

4

Small-scale

0.536

High

636563

CDC48
Cell division control protein 48

1

7

Small-scale

0.536

High

693084

PP12
Serine/threonine-protein phosphatase PP1-2

1

9

Small-scale

0.536

High

693091

PRS6B
26S proteasome regulatory subunit 6B homolog

1

2

Small-scale

0.536

High

693092

PRS7
26S proteasome regulatory subunit 7 homolog

1

5

Small-scale

0.536

High

693104

RPN1
26S proteasome regulatory subunit RPN1

1

2

Small-scale

0.536

High

693106

LSM12
Protein LSM12

1

1

Small-scale

0.536

High

693139

PRS10
26S proteasome subunit RPT4

1

6

Small-scale

0.536

High

693143

APC1
Anaphase-promoting complex subunit 1

1

2

Small-scale

0.536

High

693147

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

Small-scale

0.536

High

693152

CLU
Clustered mitochondria protein 1

1

1

Small-scale

0.536

High

693155

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.536

High

693185

APC2
Anaphase-promoting complex subunit 2

1

7

Small-scale

0.536

High

693164

RSC2
Chromatin structure-remodeling complex subunit RSC2

2

8

Small-scale

0.533

High

693159

CYK2
Cytokinesis protein 2

1

3

Small-scale

0.527

High

693151

ESP1
Separin

1

1

Small-scale

0.515

High

539704

CDC26
Anaphase-promoting complex subunit CDC26

1

0

Small-scale

0.513

High

539919

RAD9
DNA repair protein RAD9

1

0

Small-scale

0.513

High

693090

PRS6A
26S proteasome regulatory subunit 6A

1

0

Small-scale

0.513

High

693105

YHP7
Uncharacterized protein YHR097C

1

0

Small-scale

0.513

High

693109

SSP1
Sporulation-specific protein 1

1

0

Small-scale

0.513

High

693157

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.513

High

693160

DON1
Donuts protein 1

1

0

Small-scale

0.513

High

693167

HBT1
Protein HBT1

1

0

Small-scale

0.513

High

693178

APC11
Anaphase-promoting complex subunit 11

1

0

Small-scale

0.513

High

693128

COM1
DNA endonuclease SAE2

1

0

Small-scale

0.504

High

356337

H4
Histone H4

1

2

Small-scale

0.501

High

454901

CDC16
Anaphase-promoting complex subunit CDC16

1

10

Small-scale

0.501

High

693096

SGS1
ATP-dependent helicase SGS1

1

11

Small-scale

0.501

High

693099

CDC27
Anaphase-promoting complex subunit CDC27

1

8

Small-scale

0.501

High

693127

STU2
Protein STU2

1

6

Small-scale

0.501

High

588001

HSP60
Heat shock protein 60, mitochondrial

1

5

High-throughput

0.500

High

693120

IMB4
Importin subunit beta-4

1

1

High-throughput

0.500

High

693153

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.493

High

425191

CARP
Saccharopepsin

1

1

Small-scale

0.489

High

693184

YO21A
Transposon Ty2-OR1 Gag polyprotein

1

0

High-throughput

0.486

High

664710

BMH1
Protein BMH1

1

13

High-throughput

0.481

High

690514

CDC12
Cell division control protein 12

1

1

Small-scale

0.481

High

693137

NBP1
NAP1-binding protein

1

1

High-throughput

0.481

High

693094

SLD2
DNA replication regulator SLD2

1

0

Small-scale

0.480

High

693097

CENPC
Inner kinetochore subunit MIF2

1

0

Small-scale

0.480

High

693102

SWC5
SWR1-complex protein 5

1

0

High-throughput

0.480

High

693161

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.480

High

643009

BUB2
Mitotic check point protein BUB2

1

4

Small-scale

0.479

High

655547

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

2

High-throughput

0.479

High

689225

SP110
Spindle pole body component 110

1

12

Small-scale

0.479

High

693107

RT107
Regulator of Ty1 transposition protein 107

1

5

Small-scale

0.479

High

693111

MLH1
DNA mismatch repair protein MLH1

1

1

High-throughput

0.479

High

693113

ATC3
Phospholipid-transporting ATPase DRS2

1

1

Small-scale

0.479

High

693123

NDC80
Kinetochore protein NDC80

1

16

Small-scale

0.479

High

693133

MTR4
ATP-dependent RNA helicase DOB1

1

4

High-throughput

0.479

High

693163

TUS1
Rho1 guanine nucleotide exchange factor TUS1

1

6

Small-scale

0.479

High

693174

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.479

High

693172

PRM3
Pheromone-regulated membrane protein 3

1

0

High-throughput

0.460

High

141838

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.458

High

629889

YCP4
Flavoprotein-like protein YCP4

1

0

High-throughput

0.458

High

693086

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.458

High

693088

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

693108

SPC97
Spindle pole body component SPC97

1

0

Small-scale

0.458

High

693122

FDO1
Protein FDO1

1

0

High-throughput

0.458

High

693141

IPI3
Pre-rRNA-processing protein IPI3

1

0

High-throughput

0.458

High

693166

DTD
D-aminoacyl-tRNA deacylase

1

0

High-throughput

0.458

High

693168

GSHB
Glutathione synthetase GSH2

1

0

High-throughput

0.458

High

693169

SGO1
Shugoshin

1

0

High-throughput

0.458

High

693173

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.458

High

687619

YMC1
Mitochondrial glycine transporter YMC1

1

2

High-throughput

0.457

High

693183

ISA2
Iron-sulfur assembly protein 2

1

1

High-throughput

0.457

High

478019

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.445

High

490665

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

425510

PROF
Profilin

1

1

High-throughput

0.437

High

580851

ARF2
ADP-ribosylation factor 2

1

3

High-throughput

0.437

High

693148

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.437

High

693149

UTP6
U3 small nucleolar RNA-associated protein 6

1

1

High-throughput

0.437

High

693110

RIX1
Pre-rRNA-processing protein RIX1

1

0

High-throughput

0.426

High

693156

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.426

High

693158

IVY1
Protein IVY1

2

0

High-throughput

0.328

High

679844

LDS1
Outer spore wall protein LDS1

1

0

Small-scale

0.279

Low

693100

GIP1
GLC7-interacting protein 1

1

0

Small-scale

0.279

Low

693136

YD186
Uncharacterized protein YDL186W

1

0

Small-scale

0.279

Low

526833

DPOLA
DNA polymerase alpha catalytic subunit A

1

0

Small-scale

0.261

Low

693132

IRC8
Uncharacterized protein IRC8

1

0

High-throughput

0.261

Low

693118

GTT3
Glutathione transferase 3

1

0

High-throughput

0.251

Low

693093

NIC96
Nucleoporin NIC96

1

0

High-throughput

0.249

Low

693119

VTC1
Vacuolar transporter chaperone complex subunit 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024