Protein: NFKB1
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]

Gene: NFKB1
Organism: Mus musculus
Interactions: 65
UniProt ID: P25799

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

681976

TF65
Transcription factor p65

19

17

Small-scale

0.987

High

681962

NFKB1
Nuclear factor NF-kappa-B p105 subunit

4

19

Small-scale

0.887

High

681977

RELB
Transcription factor RelB

3

17

Small-scale

0.850

High

682002

IKBA
NF-kappa-B inhibitor alpha

3

18

Small-scale

0.827

High

681999

IKBZ
NF-kappa-B inhibitor zeta

2

18

Small-scale

0.793

High

682000

NFKB2
Nuclear factor NF-kappa-B p100 subunit

2

20

Small-scale

0.793

High

522150

BCL2
Apoptosis regulator Bcl-2

2

7

Small-scale

0.754

High

681978

M3K8
Mitogen-activated protein kinase kinase kinase 8

2

15

Small-scale

0.754

High

681964

NOS2
Nitric oxide synthase, inducible

6

4

Small-scale

0.721

High

681981

ANR42
Ankyrin repeat domain-containing protein 42

1

16

Small-scale

0.665

High

148652

HDAC1
Histone deacetylase 1

3

20

Small-scale

0.650

High

582535

REL
Proto-oncogene c-Rel

1

19

Small-scale

0.646

High

470392

IL6
Interleukin-6

3

6

Small-scale

0.640

High

583129

IRF1
Interferon regulatory factor 1

3

19

Small-scale

0.640

High

681967

IL12A
Interleukin-12 subunit alpha

3

4

Small-scale

0.640

High

681968

IL12B
Interleukin-12 subunit beta

3

4

Small-scale

0.640

High

681963

TNR5
Tumor necrosis factor receptor superfamily member 5

1

8

Small-scale

0.618

High

681987

RIGI
Antiviral innate immune response receptor RIG-I

1

8

High-throughput

0.618

High

681988

KC1G1
Casein kinase I isoform gamma-1

1

15

Small-scale

0.618

High

681995

ANKR1
Ankyrin repeat domain-containing protein 1

1

20

Small-scale

0.618

High

682003

FM1AA
Protein fem-1 homolog A-A

1

16

Small-scale

0.618

High

682004

HDAC6
Protein deacetylase HDAC6

1

20

Small-scale

0.618

High

313113

HDAC3
Histone deacetylase 3

2

20

Small-scale

0.584

High

378383

IFNB
Interferon beta

2

7

Small-scale

0.584

High

518939

CCL2
C-C motif chemokine 2

2

20

Small-scale

0.584

High

681997

IL23A
Interleukin-23 subunit alpha

2

3

Small-scale

0.584

High

681972

RAB3A
Ras-related protein Rab-3A

1

2

High-throughput

0.575

High

681992

RAB4B
Ras-related protein Rab-4B

1

2

High-throughput

0.575

High

681971

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

5

High-throughput

0.541

High

681989

PIAS2
E3 SUMO-protein ligase PIAS2

1

5

High-throughput

0.541

High

681990

ZN276
Zinc finger protein 276

1

6

High-throughput

0.541

High

681994

TNIP2
TNFAIP3-interacting protein 2

1

5

Small-scale

0.536

High

681996

AKAP8
A-kinase anchor protein 8

1

4

Small-scale

0.536

High

547914

NGAL
Neutrophil gelatinase-associated lipocalin

1

6

Small-scale

0.515

High

681991

GBP5
Guanylate-binding protein 5

1

2

Small-scale

0.515

High

681966

RAB17
Ras-related protein Rab-17

1

2

High-throughput

0.514

High

681982

NCOR1
Nuclear receptor corepressor 1

1

17

Small-scale

0.500

High

236485

EOMES
Eomesodermin homolog

1

4

Small-scale

0.479

High

378450

IFNG
Interferon gamma

1

2

Small-scale

0.479

High

405579

GRAB
Granzyme B(G,H)

1

5

Small-scale

0.479

High

449235

TNFA
Tumor necrosis factor

1

7

Small-scale

0.479

High

576911

HMOX1
Heme oxygenase 1

1

1

Small-scale

0.479

High

587402

RAG1
V(D)J recombination-activating protein 1

1

20

Small-scale

0.479

High

640751

RAG2
V(D)J recombination-activating protein 2

1

1

Small-scale

0.479

High

642184

TAP1
Antigen peptide transporter 1

1

3

Small-scale

0.479

High

681965

CCL5
C-C motif chemokine 5

1

20

Small-scale

0.479

High

681969

RL13
Large ribosomal subunit protein eL13

1

4

High-throughput

0.479

High

681970

IL15
Interleukin-15

1

1

Small-scale

0.479

High

681975

PAX5
Paired box protein Pax-5

1

9

Small-scale

0.479

High

681983

GBP3
Guanylate-binding protein 3

1

2

Small-scale

0.479

High

681984

HS71A
Heat shock 70 kDa protein 1A

1

20

Small-scale

0.479

High

681985

IRF4
Interferon regulatory factor 4

1

19

Small-scale

0.479

High

681986

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

1

3

Small-scale

0.479

High

682001

GBP2
Guanylate-binding protein 2

1

2

Small-scale

0.479

High

582047

IL9
Interleukin-9

1

2

Small-scale

0.470

High

533146

PERF
Perforin-1

1

0

Small-scale

0.458

High

681980

CMPK2
UMP-CMP kinase 2, mitochondrial

1

0

Small-scale

0.458

High

681998

IKBP1
Interleukin-1 receptor-associated kinase 1-binding protein 1

1

0

Small-scale

0.458

High

148474

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.457

High

681993

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

11

Small-scale

0.445

High

564895

ICAM1
Intercellular adhesion molecule 1

1

9

Small-scale

0.437

High

681973

PSME2
Proteasome activator complex subunit 2

1

3

Small-scale

0.437

High

681974

LYAM2
E-selectin

1

5

Small-scale

0.437

High

681979

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

1

High-throughput

0.407

High


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Last updated: 11Aug2025