Protein: SIC1
Protein SIC1 (CDK inhibitor p40)

Gene: SIC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 43
UniProt ID: P38634

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016242 - negative regulation of macroautophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

339604

CDK1
Cyclin-dependent kinase 1

23

1

Small-scale

0.768

High

673197

CGS5
S-phase entry cyclin-5

12

5

Small-scale

0.758

High

624730

CG23
G2/mitotic-specific cyclin-3

7

5

Small-scale

0.748

High

431130

CDC4
Cell division control protein 4

24

0

Small-scale

0.736

High

624682

CG22
G2/mitotic-specific cyclin-2

6

5

Small-scale

0.727

High

594128

CKS1
Cyclin-dependent kinases regulatory subunit

7

0

Small-scale

0.714

High

751492

SKP1
Suppressor of kinetochore protein 1

5

0

Small-scale

0.685

High

751496

CDC14
Tyrosine-protein phosphatase CDC14

4

0

Small-scale

0.671

High

624758

CG24
G2/mitotic-specific cyclin-4

3

5

Small-scale

0.660

High

691038

HOG1
Mitogen-activated protein kinase HOG1

3

0

Small-scale

0.660

High

751488

RSP5
E3 ubiquitin-protein ligase RSP5

3

0

Small-scale

0.627

High

624654

CG21
G2/mitotic-specific cyclin-1

2

5

Small-scale

0.626

High

701839

CGS6
S-phase entry cyclin-6

2

5

Small-scale

0.626

High

751500

CDC53
Cell division control protein 53

2

0

Small-scale

0.619

High

550021

CSK21
Casein kinase II subunit alpha

2

2

Small-scale

0.602

High

693703

IME2
Meiosis induction protein kinase IME2/SME1

2

1

Small-scale

0.602

High

539465

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

2

0

Small-scale

0.592

High

593394

CG12
G1/S-specific cyclin CLN2

2

6

Small-scale

0.584

High

493859

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.571

High

565572

PHO85
Cyclin-dependent protein kinase PHO85

1

1

Small-scale

0.569

High

751497

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

Small-scale

0.561

High

731695

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

0

High-throughput

0.518

High

748314

SDS24
Protein SDS24

1

0

High-throughput

0.518

High

751494

RHO5
GTP-binding protein RHO5

1

0

High-throughput

0.518

High

751499

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

1

0

High-throughput

0.518

High

751501

DPH3
Diphthamide biosynthesis protein 3

1

0

High-throughput

0.518

High

751487

NPT1
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.513

High

751489

PCL6
PHO85 cyclin-6

1

0

High-throughput

0.513

High

584724

CSK22
Casein kinase II subunit alpha'

1

1

Small-scale

0.501

High

751493

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.493

High

604791

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.480

High

618766

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

0

Small-scale

0.480

High

697078

RAD23
UV excision repair protein RAD23

1

0

Small-scale

0.480

High

751495

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

Small-scale

0.480

High

491090

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.479

High

141846

RPN13
26S proteasome regulatory subunit RPN13

1

0

Small-scale

0.458

High

751485

RPN1
26S proteasome regulatory subunit RPN1

1

0

Small-scale

0.458

High

751486

RPN10
26S proteasome regulatory subunit RPN10

1

0

Small-scale

0.458

High

751491

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

511163

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

751490

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

751498

DCR2
Phosphatase DCR2

1

0

Small-scale

0.292

High

715515

SC61G
Protein transport protein SSS1

1

0

High-throughput

0.282

High


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Last updated: 15 Jul 2024