Protein: LRC49
Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4)

Gene: LRC49, LRRC49
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q8IUZ0

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005874 - microtubule
GO:0034451 - centriolar satellite

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1068788

PCM1
Pericentriolar material 1 protein

4

4

High-throughput

0.694

High

385122

NTRK1
High affinity nerve growth factor receptor

2

20

High-throughput

0.675

High

327745

TTLL1
Polyglutamylase complex subunit TTLL1

3

1

High-throughput

0.667

High

1216994

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

3

1

High-throughput

0.667

High

968423

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.618

High

124899

EIF3F
Eukaryotic translation initiation factor 3 subunit F

3

4

High-throughput

0.609

High

1147433

TPGS2
Tubulin polyglutamylase complex subunit 2

2

0

High-throughput

0.602

High

1172554

TPGS1
Tubulin polyglutamylase complex subunit 1

2

0

High-throughput

0.602

High

1216991

NICN1
Nicolin-1

2

0

High-throughput

0.602

High

1074357

STIL
SCL-interrupting locus protein

2

1

High-throughput

0.584

High

1164948

SAS6
Spindle assembly abnormal protein 6 homolog

2

11

High-throughput

0.584

High

445856

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

20

High-throughput

0.578

High

1216983

SMG8
Nonsense-mediated mRNA decay factor SMG8

2

1

High-throughput

0.574

High

411426

INSR
Insulin receptor

1

20

High-throughput

0.553

High

537756

INSRR
Insulin receptor-related protein

1

20

High-throughput

0.553

High

665407

EPHA3
Ephrin type-A receptor 3

1

20

High-throughput

0.553

High

665495

EPHA8
Ephrin type-A receptor 8

1

20

High-throughput

0.553

High

981890

RON
Macrophage-stimulating protein receptor

1

20

High-throughput

0.553

High

1153703

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.553

High

1216980

AHI1
Jouberin

1

11

High-throughput

0.553

High

320350

SNP29
Synaptosomal-associated protein 29

1

1

High-throughput

0.536

High

1145823

CP135
Centrosomal protein of 135 kDa

2

12

High-throughput

0.533

High

343989

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.513

High

679364

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

0

High-throughput

0.513

High

73157

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

10

High-throughput

0.479

High

128593

DNM1L
Dynamin-1-like protein

1

3

High-throughput

0.479

High

166741

CE290
Centrosomal protein of 290 kDa

1

16

High-throughput

0.479

High

227969

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.479

High

230978

CE104
Centrosomal protein of 104 kDa

1

1

High-throughput

0.479

High

231120

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

4

High-throughput

0.479

High

279624

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

408857

K1C18
Keratin, type I cytoskeletal 18

1

6

High-throughput

0.479

High

409149

K2C8
Keratin, type II cytoskeletal 8

1

7

High-throughput

0.479

High

422417

NFM
Neurofilament medium polypeptide

1

12

High-throughput

0.479

High

514703

CP2C9
Cytochrome P450 2C9

1

1

High-throughput

0.479

High

776734

STAT3
Signal transducer and activator of transcription 3

1

2

High-throughput

0.479

High

835866

GSK3B
Glycogen synthase kinase-3 beta

1

12

High-throughput

0.479

High

921636

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.479

High

995014

GOGA2
Golgin subfamily A member 2

1

10

High-throughput

0.479

High

1033290

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

1038510

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.479

High

1076651

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1100879

MOONR
Protein moonraker

1

1

High-throughput

0.479

High

1115633

CCD14
Coiled-coil domain-containing protein 14

1

1

High-throughput

0.479

High

1124550

ODFP2
Outer dense fiber protein 2

1

12

High-throughput

0.479

High

1135940

CE162
Centrosomal protein of 162 kDa

1

14

High-throughput

0.479

High

1174207

MOB2
MOB kinase activator 2

1

3

High-throughput

0.479

High

1205973

MIB1
E3 ubiquitin-protein ligase MIB1

1

9

High-throughput

0.479

High

1216979

CNTRB
Centrobin

1

8

High-throughput

0.479

High

1216982

CE120
Centrosomal protein of 120 kDa

1

9

High-throughput

0.479

High

1216988

CEP63
Centrosomal protein of 63 kDa

1

11

High-throughput

0.479

High

1216989

CK5P2
CDK5 regulatory subunit-associated protein 2

1

14

High-throughput

0.479

High

1216995

MOB1A
MOB kinase activator 1A

1

3

High-throughput

0.479

High

1216996

CENPJ
Centromere protein J

1

9

High-throughput

0.479

High

1216998

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1217003

MYO6
Unconventional myosin-VI

1

6

High-throughput

0.479

High

1217004

FBW1A
F-box/WD repeat-containing protein 1A

1

6

High-throughput

0.479

High

1217005

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.479

High

1217006

PHOCN
MOB-like protein phocein

1

3

High-throughput

0.479

High

264589

MTX2
Metaxin-2

1

0

High-throughput

0.458

High

518702

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

880962

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

1216978

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

1216990

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1216992

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1217001

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.458

High

118359

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.437

High

155027

NDC80
Kinetochore protein NDC80 homolog

1

14

High-throughput

0.437

High

296939

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.437

High

318180

DIRA3
GTP-binding protein Di-Ras3

1

8

High-throughput

0.437

High

583340

HXK1
Hexokinase-1

1

1

High-throughput

0.437

High

583516

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.437

High

654510

CALX
Calnexin

1

6

High-throughput

0.437

High

657519

TMOD1
Tropomodulin-1

1

1

High-throughput

0.437

High

716727

CTNA1
Catenin alpha-1

1

4

High-throughput

0.437

High

823437

PAXI
Paxillin

1

5

High-throughput

0.437

High

895159

RAB2A
Ras-related protein Rab-2A

1

13

High-throughput

0.437

High

1053058

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

7

High-throughput

0.437

High

1067445

EEA1
Early endosome antigen 1

1

10

High-throughput

0.437

High

1151946

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1159177

PRP8
Pre-mRNA-processing-splicing factor 8

1

3

High-throughput

0.437

High

1172666

CE128
Centrosomal protein of 128 kDa

1

13

High-throughput

0.437

High

1216977

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.437

High

1216985

AKAP1
A-kinase anchor protein 1, mitochondrial

1

3

High-throughput

0.437

High

1216986

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.437

High

1216987

PF21A
PHD finger protein 21A

1

8

High-throughput

0.437

High

240081

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

1155830

SANBR
SANT and BTB domain regulator of class switch recombination

2

0

High-throughput

0.328

High

1216981

TBC19
TBC1 domain family member 19

2

0

High-throughput

0.328

High

642854

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1139293

SPAT1
Spermatogenesis-associated protein 1

1

0

High-throughput

0.279

Low

232299

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

273880

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

304848

MFN2
Mitofusin-2

1

0

High-throughput

0.249

Low

825463

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

1204278

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1216984

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.249

Low

1216993

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

1216997

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.249

Low

1216999

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.249

Low

1217000

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

1217002

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

1217007

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024