Protein: INO80
Chromatin-remodeling ATPase INO80 (EC 3.6.4.-) (Inositol-requiring protein 80)

Gene: INO80
Organism: Saccharomyces cerevisiae S288C
Interactions: 132
UniProt ID: P53115

Gene Ontology (top 5):
GO:0000722 - telomere maintenance via recombination
GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

859293

ARP8
Actin-like protein ARP8

22

20

Small-scale

0.988

High

859294

RUVB2
RuvB-like protein 2

21

20

Small-scale

0.988

High

859261

ARP4
Actin-related protein 4

21

20

Small-scale

0.986

High

859271

RUVB1
RuvB-like protein 1

19

20

Small-scale

0.986

High

859259

ACT
Actin

19

20

Small-scale

0.986

High

859256

ARP5
Actin-related protein 5

16

20

Small-scale

0.983

High

355556

H2B1
Histone H2B.1

5

20

Small-scale

0.906

High

392161

H2A1
Histone H2A.1

4

20

Small-scale

0.878

High

356605

H4
Histone H4

4

15

Small-scale

0.873

High

859260

H3
Histone H3

4

20

Small-scale

0.873

High

859268

NHP10
Non-histone protein 10

19

20

Small-scale

0.764

High

715711

TAF14
Transcription initiation factor TFIID subunit 14

19

8

Small-scale

0.764

High

859292

IES3
Ino eighty subunit 3

17

2

Small-scale

0.761

High

797262

IES1
Ino eighty subunit 1

16

1

Small-scale

0.761

High

696942

IES6
Chromatin-remodeling complex subunit IES6

14

3

Small-scale

0.757

High

767486

IES5
Ino eighty subunit 5

14

1

Small-scale

0.757

High

859284

IES4
Ino eighty subunit 4

14

1

Small-scale

0.757

High

769963

IES2
Ino eighty subunit 2

13

2

Small-scale

0.755

High

859252

INO80
Chromatin-remodeling ATPase INO80

2

18

Small-scale

0.754

High

392509

H2A2
Histone H2A.2

2

20

Small-scale

0.737

High

355948

H2B2
Histone H2B.2

1

20

Small-scale

0.618

High

558165

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.618

High

687721

BTAF1
TATA-binding protein-associated factor MOT1

1

18

Small-scale

0.618

High

730862

CENPA
Histone H3-like centromeric protein CSE4

1

20

High-throughput

0.618

High

775563

MPH1
ATP-dependent DNA helicase MPH1

1

20

High-throughput

0.618

High

607310

RFA1
Replication factor A protein 1

2

11

Small-scale

0.584

High

636687

CDC48
Cell division control protein 48

1

4

Small-scale

0.561

High

693044

RPD3
Histone deacetylase RPD3

1

20

Small-scale

0.561

High

744155

ATR
Serine/threonine-protein kinase MEC1

1

9

Small-scale

0.561

High

494493

HSP72
Heat shock protein SSA2

2

17

High-throughput

0.552

High

784468

FKH2
Fork head protein homolog 2

1

20

High-throughput

0.536

High

859267

GCN5
Histone acetyltransferase GCN5

1

20

High-throughput

0.536

High

859278

YL455
PWWP domain-containing protein YLR455W

1

9

Small-scale

0.536

High

540124

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.489

High

763435

MET10
Sulfite reductase [NADPH] flavoprotein component

1

2

High-throughput

0.489

High

784973

GLDS1
Protein GDS1

1

0

High-throughput

0.486

High

375450

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

10

Small-scale

0.479

High

539900

RAD4
DNA repair protein RAD4

1

2

Small-scale

0.479

High

662816

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

664950

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

688334

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

703827

PRS6B
26S proteasome regulatory subunit 6B homolog

1

3

Small-scale

0.479

High

703932

PRS7
26S proteasome regulatory subunit 7 homolog

1

5

Small-scale

0.479

High

716294

SPT10
Protein SPT10

1

3

High-throughput

0.479

High

728285

DEF1
RNA polymerase II degradation factor 1

1

7

Small-scale

0.479

High

746076

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

6

Small-scale

0.479

High

748992

PAF1
RNA polymerase II-associated protein 1

1

3

Small-scale

0.479

High

750624

LEO1
RNA polymerase-associated protein LEO1

1

5

Small-scale

0.479

High

765768

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

8

Small-scale

0.479

High

775786

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.479

High

797484

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

9

Small-scale

0.479

High

805216

TAF1
Transcription initiation factor TFIID subunit 1

1

4

High-throughput

0.479

High

810993

UBX6
UBX domain-containing protein 6

1

1

Small-scale

0.479

High

859253

H1
Histone H1

1

1

Small-scale

0.479

High

859258

ORC1
Origin recognition complex subunit 1

1

5

High-throughput

0.479

High

859262

CTR9
RNA polymerase-associated protein CTR9

1

12

Small-scale

0.479

High

859270

TAF12
Transcription initiation factor TFIID subunit 12

1

6

High-throughput

0.479

High

859272

RPN9
26S proteasome regulatory subunit RPN9

1

2

Small-scale

0.479

High

859273

SIZ1
E3 SUMO-protein ligase SIZ1

1

7

High-throughput

0.479

High

859277

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

859281

CDC73
Cell division control protein 73

1

2

Small-scale

0.479

High

859287

SCC1
Sister chromatid cohesion protein 1

1

5

High-throughput

0.479

High

859288

SIZ2
E3 SUMO-protein ligase SIZ2

1

6

High-throughput

0.479

High

141862

RPN13
26S proteasome regulatory subunit RPN13

1

0

Small-scale

0.458

High

294146

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.458

High

608471

SAN1
Protein SAN1

1

0

Small-scale

0.458

High

619494

PSA2
Proteasome subunit alpha type-2

1

0

Small-scale

0.458

High

689193

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.458

High

691491

RPN12
26S proteasome regulatory subunit RPN12

1

0

Small-scale

0.458

High

743439

GLRX7
Monothiol glutaredoxin-7

1

0

High-throughput

0.458

High

819974

HOSC
Homocitrate synthase, cytosolic isozyme

1

0

Small-scale

0.458

High

858831

RTF1
RNA polymerase-associated protein RTF1

1

0

Small-scale

0.458

High

859257

UBX4
UBX domain-containing protein 4

1

0

Small-scale

0.458

High

859265

ESP1
Separin

1

0

High-throughput

0.458

High

859274

LCD1
DNA damage checkpoint protein LCD1

1

0

Small-scale

0.458

High

859276

NEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.458

High

859290

MDY2
Ubiquitin-like protein MDY2

1

0

Small-scale

0.458

High

759311

MET30
F-box protein MET30

1

12

High-throughput

0.457

High

366614

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

388997

SYTC
Threonine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

419364

HAP2
Transcriptional activator HAP2

1

3

High-throughput

0.445

High

491882

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.445

High

512059

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.445

High

514194

NHP6A
Non-histone chromosomal protein 6A

1

20

High-throughput

0.445

High

519977

TCPA
T-complex protein 1 subunit alpha

1

2

High-throughput

0.445

High

544111

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.445

High

556179

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.445

High

560739

BIP
Endoplasmic reticulum chaperone BiP

1

12

High-throughput

0.445

High

605243

AFT1
Iron-regulated transcriptional activator AFT1

1

1

High-throughput

0.445

High

633403

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

641007

RL5
Large ribosomal subunit protein uL18

1

4

High-throughput

0.445

High

680873

HS104
Heat shock protein 104

1

5

High-throughput

0.445

High

689915

ASF1
Histone chaperone ASF1

1

9

High-throughput

0.445

High

690847

HIR1
Protein HIR1

1

20

High-throughput

0.445

High

692569

ZUO1
Zuotin

1

6

High-throughput

0.445

High

695130

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

705443

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.445

High

733275

SET3
SET domain-containing protein 3

1

17

High-throughput

0.445

High

742898

GBLP
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.445

High

754559

SSZ1
Ribosome-associated complex subunit SSZ1

1

13

High-throughput

0.445

High

760657

TCPB
T-complex protein 1 subunit beta

1

3

High-throughput

0.445

High

770094

RT106
Histone chaperone RTT106

1

2

High-throughput

0.445

High

772300

ATAD2
ATPase histone chaperone YTA7

1

7

High-throughput

0.445

High

859263

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

20

High-throughput

0.445

High

859275

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

20

High-throughput

0.445

High

859283

RSC58
Chromatin structure-remodeling complex protein RSC58

1

2

High-throughput

0.445

High

859295

RLF2
Chromatin assembly factor 1 subunit p90

1

10

High-throughput

0.445

High

697101

RAD23
UV excision repair protein RAD23

1

4

Small-scale

0.437

High

748974

UBX7
UBX domain-containing protein 7

1

1

Small-scale

0.437

High

768273

SCC4
MAU2 chromatid cohesion factor homolog

1

3

Small-scale

0.437

High

859266

RT10
Small ribosomal subunit protein uS10m

1

3

High-throughput

0.437

High

859285

RPN8
26S proteasome regulatory subunit RPN8

1

4

Small-scale

0.437

High

859289

RPN5
26S proteasome regulatory subunit RPN5

1

2

Small-scale

0.437

High

424619

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

498555

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.426

High

333858

ADH1
Alcohol dehydrogenase 1

1

2

High-throughput

0.407

High

368247

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.407

High

804811

RSSA2
Small ribosomal subunit protein uS2B

1

3

High-throughput

0.407

High

859264

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.407

High

859280

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

4

High-throughput

0.407

High

859291

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

859296

ATG11
Autophagy-related protein 11

1

0

Small-scale

0.292

High

791229

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.249

Low

811701

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.249

Low

859254

ATG2
Autophagy-related protein 2

1

0

Small-scale

0.249

Low

859255

PGA14
Hydrophilin YNL190W

1

0

High-throughput

0.249

Low

859269

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

859279

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.249

Low

859282

ATG20
Autophagy-related protein 20

1

0

Small-scale

0.249

Low

859286

ATG9
Autophagy-related protein 9

1

0

Small-scale

0.249

Low

785118

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024