HitPredict - High confidence protein-protein interactions

Protein: THI6
Probable thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase); Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (THZ kinase)]

Gene: THI6, thi4
Organism: Schizosaccharomyces pombe 972h-
Interactions: 9
UniProt ID: P40386

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004417 - hydroxyethylthiazole kinase activity
GO:0004789 - thiamine-phosphate diphosphorylase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
823578	THI6 Probable thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase	1	3	High-throughput	0.621	High
313972	IMA2 Importin subunit alpha-2	1	1	High-throughput	0.481	High
823580	DJ1 Glutathione-independent glyoxalase DJ-1	1	1	High-throughput	0.479	High
823579	TFS2 Transcription elongation factor S-II	1	0	High-throughput	0.460	High
153525	PUR4 Phosphoribosylformylglycinamidine synthase	1	1	Small-scale	0.445	High
206827	YF75 Uncharacterized protein C3G9.05	1	0	High-throughput	0.251	Low
149325	PMT3 Ubiquitin-like protein pmt3/smt3	1	0	High-throughput	0.249	Low
823581	PTR2 Probable peptide transporter ptr2	1	0	Small-scale	0.232	Low

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Last updated: 11Aug2025