Protein: DSC1
DSC E3 ubiquitin ligase complex subunit 1 (EC 2.3.2.27) (Defective for SREBP cleavage protein 1) (RING-type E3 ubiquitin transferase DSC1)

Gene: DSC1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 28
UniProt ID: O43085

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

207336

DSC2
DSC E3 ubiquitin ligase complex subunit 2

5

1

Small-scale

0.709

High

207324

UBC4
Ubiquitin-conjugating enzyme E2 4

1

2

Small-scale

0.647

High

207313

DSC1
DSC E3 ubiquitin ligase complex subunit 1

1

0

Small-scale

0.614

High

207316

UCP10
UBX domain-containing protein 10

2

1

Small-scale

0.584

High

207334

DSC3
DSC E3 ubiquitin ligase complex subunit 3

2

1

Small-scale

0.584

High

153351

DSC4
DSC E3 ubiquitin ligase complex subunit 4

1

0

Small-scale

0.458

High

207323

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

Small-scale

0.458

High

207327

YDJ8
Abhydrolase domain-containing protein C57A10.08c

1

0

Small-scale

0.458

High

207328

YDM7
Uncharacterized protein C57A7.07c

1

0

Small-scale

0.458

High

207335

CDC48
Cell division cycle protein 48

1

0

Small-scale

0.458

High

207333

SSB1
Ribosome-associated molecular chaperone sks2

1

1

Small-scale

0.437

High

150710

RL8
Large ribosomal subunit protein eL8

1

0

Small-scale

0.249

Low

206932

OGA1
Ribosome-associated protein oga1

1

0

Small-scale

0.249

Low

207314

HSP72
Probable heat shock protein ssa2

1

0

Small-scale

0.249

Low

207315

RL7C
Large ribosomal subunit protein uL30C

1

0

Small-scale

0.249

Low

207317

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.249

Low

207318

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.249

Low

207319

RL35
Large ribosomal subunit protein uL29

1

0

Small-scale

0.249

Low

207320

RS3A2
Small ribosomal subunit protein eS1B

1

0

Small-scale

0.249

Low

207321

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.249

Low

207322

RL4A
Large ribosomal subunit protein uL4A

1

0

Small-scale

0.249

Low

207325

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

0

Small-scale

0.249

Low

207326

RL6
Large ribosomal subunit protein eL6

1

0

Small-scale

0.249

Low

207329

RL22
Large ribosomal subunit protein eL22

1

0

Small-scale

0.249

Low

207330

YA78
Uncharacterized protein C24H6.08

1

0

Small-scale

0.249

Low

207331

RS7
Small ribosomal subunit protein eS7

1

0

Small-scale

0.249

Low

207332

KPYK
Pyruvate kinase

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025