Protein: FBX21
F-box only protein 21

Gene: FBX21, FBXO21
Organism: Homo sapiens
Interactions: 59
UniProt ID: O94952

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003677 - DNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

301088

CUL1
Cullin-1

5

1

Small-scale

0.925

High

301085

SKP1
S-phase kinase-associated protein 1

5

0

Small-scale

0.877

High

301084

RBX1
E3 ubiquitin-protein ligase RBX1

3

0

Small-scale

0.638

High

301089

CUL3
Cullin-3

1

1

High-throughput

0.618

High

301066

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.614

High

301071

IDS
Iduronate 2-sulfatase

3

6

High-throughput

0.609

High

301070

KPCA
Protein kinase C alpha type

2

0

High-throughput

0.602

High

301062

CRYAB
Alpha-crystallin B chain

2

0

High-throughput

0.585

High

301075

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

2

0

High-throughput

0.585

High

301104

VWCE
von Willebrand factor C and EGF domain-containing protein

2

1

High-throughput

0.574

High

301105

ARSG
Arylsulfatase G

2

6

High-throughput

0.574

High

301091

NEDD8
NEDD8

1

0

High-throughput

0.546

High

301068

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

301072

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.513

High

301073

PRTN3
Myeloblastin

1

0

High-throughput

0.513

High

301099

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.513

High

301103

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

147467

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.493

High

301069

ARSA
Arylsulfatase A

1

6

High-throughput

0.489

High

301074

GALNS
N-acetylgalactosamine-6-sulfatase

1

6

High-throughput

0.489

High

301078

SPHM
N-sulphoglucosamine sulphohydrolase

1

6

High-throughput

0.489

High

301079

ARSL
Arylsulfatase L

1

6

High-throughput

0.489

High

301092

ARSI
Arylsulfatase I

1

6

High-throughput

0.489

High

301081

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.479

High

148238

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

209549

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

301063

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

301064

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

301076

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.458

High

301082

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

301083

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

301087

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

301095

CDC73
Parafibromin

1

0

High-throughput

0.458

High

301107

COL11
Collectin-11

1

0

High-throughput

0.458

High

301109

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

Small-scale

0.458

High

301111

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

301113

ARI1
E3 ubiquitin-protein ligase ARIH1

1

0

High-throughput

0.458

High

301090

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.437

High

301061

CEP43
Centrosomal protein 43

1

0

Small-scale

0.426

High

301067

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

301080

NUP98
Nuclear pore complex protein Nup98-Nup96

1

0

Small-scale

0.426

High

301106

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

301110

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

Small-scale

0.426

High

301115

EID1
EP300-interacting inhibitor of differentiation 1

4

0

Small-scale

0.373

High

246318

KERA
Keratocan

2

0

High-throughput

0.328

High

301086

FBLN2
Fibulin-2

1

0

High-throughput

0.279

Low

301096

CF015
Uncharacterized protein C6orf15

1

0

High-throughput

0.279

Low

301112

TINAG
Tubulointerstitial nephritis antigen

1

0

High-throughput

0.279

Low

301108

CNTP4
Contactin-associated protein-like 4

1

0

Small-scale

0.265

Low

301065

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

301077

CCN3
CCN family member 3

1

0

High-throughput

0.249

Low

301093

TENS2
Tensin-2

1

0

High-throughput

0.249

Low

301097

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

301098

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

301100

ZBT46
Zinc finger and BTB domain-containing protein 46

1

0

High-throughput

0.249

Low

301101

F219A
Protein FAM219A

1

0

High-throughput

0.249

Low

301102

EID2
EP300-interacting inhibitor of differentiation 2

1

0

Small-scale

0.249

Low

301094

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

0

Small-scale

0.232

Low

301114

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024