Protein: SPF30
Survival of motor neuron-related-splicing factor 30 (30 kDa splicing factor SMNrp) (SMN-related protein) (Survival motor neuron domain-containing protein 1)

Gene: SPF30, SMNDC1
Organism: Homo sapiens
Interactions: 91
UniProt ID: O75940

Gene Ontology (top 5):
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

278934

SF3B2
Splicing factor 3B subunit 2

3

1

High-throughput

0.662

High

268548

SF3B1
Splicing factor 3B subunit 1

3

0

High-throughput

0.643

High

278944

SF3A1
Splicing factor 3A subunit 1

2

1

High-throughput

0.628

High

278943

SF3A2
Splicing factor 3A subunit 2

3

0

Small-scale

0.628

High

278909

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

3

Small-scale

0.611

High

278937

RBM39
RNA-binding protein 39

2

3

High-throughput

0.611

High

278929

EWS
RNA-binding protein EWS

2

6

High-throughput

0.601

High

278931

SF3A3
Splicing factor 3A subunit 3

2

0

High-throughput

0.595

High

278898

RECQ4
ATP-dependent DNA helicase Q4

2

4

High-throughput

0.584

High

278899

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

202345

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.549

High

165357

SR140
U2 snRNP-associated SURP motif-containing protein

1

4

High-throughput

0.536

High

278904

SNRPA
U1 small nuclear ribonucleoprotein A

1

4

High-throughput

0.536

High

278905

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

278907

POTEI
POTE ankyrin domain family member I

1

1

High-throughput

0.536

High

278923

RUXF
Small nuclear ribonucleoprotein F

1

6

High-throughput

0.536

High

278936

CUL3
Cullin-3

1

1

High-throughput

0.536

High

278921

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.527

High

278955

ARHGJ
Rho guanine nucleotide exchange factor 19

2

3

High-throughput

0.521

High

278911

NUCL
Nucleolin

1

1

High-throughput

0.515

High

278942

SF3B4
Splicing factor 3B subunit 4

1

5

High-throughput

0.515

High

278971

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.515

High

255010

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

278910

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.513

High

278935

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

278950

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.513

High

278918

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.493

High

278941

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.493

High

278947

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.493

High

278963

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.493

High

278969

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.493

High

278970

SSF1
Suppressor of SWI4 1 homolog

1

0

High-throughput

0.493

High

278977

RUVB1
RuvB-like 1

1

0

High-throughput

0.493

High

278976

PRP19
Pre-mRNA-processing factor 19

1

3

High-throughput

0.481

High

271987

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

3

Small-scale

0.479

High

278900

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

278901

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

278902

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

278906

RU2A
U2 small nuclear ribonucleoprotein A'

1

3

High-throughput

0.479

High

278912

DNJB1
DnaJ homolog subfamily B member 1

1

1

High-throughput

0.479

High

278914

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

278916

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

278917

COIL
Coilin

1

1

High-throughput

0.479

High

278919

RECQ1
ATP-dependent DNA helicase Q1

1

5

High-throughput

0.479

High

278920

MAPK2
MAP kinase-activated protein kinase 2

1

1

High-throughput

0.479

High

278922

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

278925

H4
Histone H4

1

1

High-throughput

0.479

High

278926

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

278927

H31
Histone H3.1

1

3

High-throughput

0.479

High

278928

VIGLN
Vigilin

1

6

High-throughput

0.479

High

278938

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

High-throughput

0.479

High

278939

IMB1
Importin subunit beta-1

1

2

Small-scale

0.479

High

278940

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

278945

ITSN1
Intersectin-1

1

2

High-throughput

0.479

High

278949

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.479

High

278952

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.479

High

278953

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

278958

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

278962

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

278964

DDX50
ATP-dependent RNA helicase DDX50

1

4

High-throughput

0.479

High

278966

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

278967

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

278973

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

278974

WWC3
Protein WWC3

1

3

High-throughput

0.479

High

278975

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

278979

SF3B6
Splicing factor 3B subunit 6

1

5

High-throughput

0.479

High

278981

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

243723

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

278903

PGK2
Phosphoglycerate kinase 2

1

0

High-throughput

0.458

High

278924

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

278933

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

278956

PDCD7
Programmed cell death protein 7

1

0

High-throughput

0.458

High

278960

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

278961

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

278965

GNL3
Guanine nucleotide-binding protein-like 3

1

0

High-throughput

0.458

High

278972

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

278980

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

278908

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

278913

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

278968

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

148228

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

278930

LMNB2
Lamin-B2

1

1

High-throughput

0.437

High

278932

IFT88
Intraflagellar transport protein 88 homolog

1

1

High-throughput

0.437

High

278951

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.437

High

278959

PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

1

3

High-throughput

0.437

High

278978

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

278948

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

278946

H31T
Histone H3.1t

1

3

Small-scale

0.408

High

278954

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

278957

GPT11
G patch domain-containing protein 11

1

0

High-throughput

0.279

Low

278915

FDFT
Squalene synthase

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024