Protein: CWC2
Pre-mRNA-splicing factor cwf2 (Complexed with cdc5 protein 2) (Pre-mRNA-processing protein 3)

Gene: CWC2, cwf2
Organism: Schizosaccharomyces pombe 972h-
Interactions: 99
UniProt ID: P87126

Gene Ontology (top 5):
GO:0000387 - spliceosomal snRNP assembly
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1018016

RU2A
U2 small nuclear ribonucleoprotein A'

3

6

High-throughput

0.849

High

268056

CWF14
Pre-mRNA-splicing factor cwf14

2

4

Small-scale

0.789

High

1017983

CWC2
Pre-mRNA-splicing factor cwf2

2

16

Small-scale

0.754

High

153394

SPP42
Pre-mRNA-splicing factor spp42

1

7

High-throughput

0.691

High

237788

SLT11
Pre-mRNA-splicing factor cwf5

1

16

High-throughput

0.691

High

267537

ISY1
Pre-mRNA-splicing factor cwf12

1

2

High-throughput

0.691

High

1017992

PRP45
Pre-mRNA-processing protein 45

1

6

High-throughput

0.691

High

313690

SN114
Pre-mRNA-splicing factor cwf10

3

6

Small-scale

0.650

High

1018007

YK96
Uncharacterized protein C20H4.06c

3

1

High-throughput

0.640

High

152542

PRP19
Pre-mRNA-processing factor 19

2

6

Small-scale

0.626

High

151825

RSD1
RNA-binding protein rsd1

1

15

High-throughput

0.618

High

152801

SAP49
Spliceosome-associated protein 49

1

15

High-throughput

0.618

High

237582

SAP61
Pre-mRNA-splicing factor sap61

1

2

High-throughput

0.618

High

267870

BBP
Branchpoint-bridging protein

1

7

High-throughput

0.618

High

313932

YHOC
Uncharacterized RNA-binding protein C428.12c

1

16

High-throughput

0.618

High

314077

CWC26
Pre-mRNA-splicing factor cwf26

1

1

High-throughput

0.618

High

785786

U2AF2
Splicing factor U2AF 59 kDa subunit

1

16

High-throughput

0.618

High

1017861

PPIL1
Peptidyl-prolyl cis-trans isomerase ppi1

1

4

High-throughput

0.618

High

1017996

SF3B1
U2 snRNP component prp10

1

3

High-throughput

0.618

High

1018001

YDC1
Uncharacterized RNA-binding protein C25G10.01

1

20

High-throughput

0.618

High

1018004

RU2B
Probable U2 small nuclear ribonucleoprotein B''

1

18

High-throughput

0.618

High

1018010

SAP62
Pre-mRNA-splicing factor sap62

1

3

High-throughput

0.618

High

1018023

RSE1
Pre-mRNA-splicing factor prp12

1

3

High-throughput

0.618

High

1018026

SA145
Pre-mRNA-splicing factor sap145

1

2

High-throughput

0.618

High

152846

SDE2
Splicing regulator sde2

3

0

Small-scale

0.613

High

1018018

BRR2
Pre-mRNA-splicing factor brr2

2

17

High-throughput

0.611

High

1018006

YK99
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09

2

12

High-throughput

0.584

High

1018020

YKR3
G-patch domain-containing protein C1486.03

2

4

High-throughput

0.584

High

150431

PRP46
Pre-mRNA-splicing factor prp5

1

8

High-throughput

0.536

High

205933

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22

1

10

High-throughput

0.536

High

205999

SMD1
Small nuclear ribonucleoprotein Sm D1

1

9

High-throughput

0.536

High

207262

PRP17
Pre-mRNA-processing factor 17

1

6

High-throughput

0.536

High

237606

SYF2
Pre-mRNA-splicing factor syf2

1

1

High-throughput

0.536

High

237619

RUXF
Small nuclear ribonucleoprotein F

1

10

High-throughput

0.536

High

268769

RUXG
Small nuclear ribonucleoprotein G

1

15

High-throughput

0.536

High

314272

CWF11
Pre-mRNA-splicing factor cwf11

1

9

High-throughput

0.536

High

314609

CWF17
Pre-mRNA-splicing factor cwf17

1

5

High-throughput

0.536

High

1008962

CWC15
Pre-mRNA-splicing factor cwf15

1

1

High-throughput

0.536

High

1017984

CLF1
Pre-mRNA-splicing factor cwf4

1

14

High-throughput

0.536

High

1017987

DRE4
Pre-mRNA-splicing factor dre4

1

3

High-throughput

0.536

High

1017993

CWF19
Pre-mRNA-splicing factor cwf19

1

2

High-throughput

0.536

High

1017995

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

12

High-throughput

0.536

High

1018008

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16

1

10

High-throughput

0.536

High

1018011

SYF1
Pre-mRNA-splicing factor cwf3

1

13

High-throughput

0.536

High

1018017

RUXE
Small nuclear ribonucleoprotein E

1

2

High-throughput

0.536

High

1018024

CWF18
Pre-mRNA-splicing factor cwf18

1

1

High-throughput

0.536

High

1018025

SMD3
Small nuclear ribonucleoprotein Sm D3

1

10

High-throughput

0.536

High

1018028

CWC25
Pre-mRNA-splicing factor cwf25

1

3

High-throughput

0.536

High

1018015

SPF27
Pre-mRNA-splicing factor cwf7

1

0

High-throughput

0.530

High

152772

YERE
WW domain-containing protein C2F3.14c

1

0

High-throughput

0.513

High

153324

CWC21
Pre-mRNA-splicing factor cwf21

1

0

High-throughput

0.513

High

151208

YF28
Uncharacterized protein C17A2.08c

1

1

High-throughput

0.479

High

151384

SUB2
ATP-dependent RNA helicase uap56

1

19

High-throughput

0.479

High

151553

YE02
Uncharacterized helicase C17H9.02

1

20

High-throughput

0.479

High

151934

SA114
Pre-mRNA-splicing factor sap114

1

4

High-throughput

0.479

High

151949

ACL2
Probable ATP-citrate synthase subunit 2

1

1

High-throughput

0.479

High

207021

DHX15
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43

1

9

High-throughput

0.479

High

237746

ESS2
Stress response protein bis1

1

1

High-throughput

0.479

High

237926

YBB2
Probable mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.479

High

547739

YPT1
GTP-binding protein ypt1

1

1

High-throughput

0.479

High

704909

SPI1
GTP-binding nuclear protein spi1

1

4

High-throughput

0.479

High

1017985

GAR1
H/ACA ribonucleoprotein complex subunit gar1

1

1

High-throughput

0.479

High

1017989

DBP5
ATP-dependent RNA helicase dbp5

1

16

High-throughput

0.479

High

1017994

TCPB
Probable T-complex protein 1 subunit beta

1

2

High-throughput

0.479

High

1017998

MET16
Probable phosphoadenosine phosphosulfate reductase

1

2

High-throughput

0.479

High

1018000

MU161
CWF19-like protein mug161

1

2

High-throughput

0.479

High

1018003

CDC28
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28

1

10

High-throughput

0.479

High

1018005

YN55
Uncharacterized WD repeat-containing protein C713.05

1

7

High-throughput

0.479

High

1018012

ACL1
Probable ATP-citrate synthase subunit 1

1

2

High-throughput

0.479

High

1018014

LUC7
U1 snRNP-associated protein usp106

1

5

High-throughput

0.479

High

1018019

INI1
Pre-mRNA-splicing factor ini1

1

2

High-throughput

0.479

High

1018022

RED1
NURS complex subunit red1

1

1

High-throughput

0.479

High

151755

RFP1
E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1

1

0

High-throughput

0.458

High

153545

ERG20
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.458

High

153658

YE6A
Uncharacterized protein C6G10.10c

1

0

High-throughput

0.458

High

154014

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

206036

TAL1
Transaldolase

1

0

High-throughput

0.458

High

313778

PIR2
NURS complex subunit pir2

1

0

High-throughput

0.458

High

314293

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.458

High

314469

TRPE
Probable anthranilate synthase component 1

1

0

High-throughput

0.458

High

940523

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

1017990

AROF
Putative phospho-2-dehydro-3-deoxyheptonate aldolase

1

0

High-throughput

0.458

High

1018013

YJIA
Uncharacterized protein C5E4.10c

1

0

High-throughput

0.458

High

238176

CWC16
Protein saf4

1

3

High-throughput

0.445

High

152593

SYSC
Serine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.437

High

237809

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.437

High

268755

PIL1
Probable sphingolipid long chain base-responsive protein pil1

1

1

High-throughput

0.437

High

868860

IF4A
ATP-dependent RNA helicase eIF4A

1

18

High-throughput

0.437

High

1017986

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.437

High

1017988

CP51
Lanosterol 14-alpha demethylase erg11

1

1

High-throughput

0.437

High

1018002

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

1018021

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.437

High

1018009

YLK3
Uncharacterized protein C1782.03

1

0

High-throughput

0.426

High

153527

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.249

Low

1017991

HXK1
Hexokinase-1

1

0

High-throughput

0.249

Low

1017997

MUG64
Meiotically up-regulated gene 64 protein

1

0

High-throughput

0.249

Low

1017999

SERC
Putative phosphoserine aminotransferase

1

0

High-throughput

0.249

Low

1018027

SYQ
Probable glutamine--tRNA ligase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025