Protein: SEPT2
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)

Gene: SEPT2, SEPTIN2
Organism: Homo sapiens
Interactions: 131
UniProt ID: Q15019

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1048992

SEPT6
Septin-6

12

19

Small-scale

0.983

High

1063176

SEPT5
Septin-5

9

19

Small-scale

0.979

High

1063141

SEPT7
Septin-7

7

19

Small-scale

0.965

High

1063197

SEPT9
Septin-9

7

19

Small-scale

0.965

High

1063191

SEP11
Septin-11

6

19

High-throughput

0.947

High

1063163

SEPT8
Septin-8

5

19

High-throughput

0.927

High

1063194

SEP10
Septin-10

4

19

High-throughput

0.903

High

1063196

SEPT3
Neuronal-specific septin-3

4

19

High-throughput

0.903

High

1063156

SEP12
Septin-12

4

19

Small-scale

0.899

High

1063160

SEPT1
Septin-1

3

19

High-throughput

0.861

High

198191

SEPT4
Septin-4

2

20

High-throughput

0.811

High

1063150

SEP14
Septin-14

2

19

Small-scale

0.783

High

1063136

SEPT2
Septin-2

1

19

Small-scale

0.692

High

1063182

BORG4
Cdc42 effector protein 4

3

14

High-throughput

0.667

High

1063190

ANLN
Anillin

3

10

High-throughput

0.656

High

227485

PRKN
E3 ubiquitin-protein ligase parkin

3

12

High-throughput

0.640

High

834902

RGS3
Regulator of G-protein signaling 3

2

5

High-throughput

0.628

High

502114

BIP
Endoplasmic reticulum chaperone BiP

2

8

High-throughput

0.611

High

1063140

EZH2
Histone-lysine N-methyltransferase EZH2

2

4

High-throughput

0.611

High

1063199

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

2

7

High-throughput

0.606

High

894021

CDC42
Cell division control protein 42 homolog

2

10

High-throughput

0.595

High

1063166

SH3K1
SH3 domain-containing kinase-binding protein 1

2

7

Small-scale

0.595

High

998724

EP300
Histone acetyltransferase p300

2

5

High-throughput

0.584

High

1063157

TBC21
TBC1 domain family member 21

2

0

High-throughput

0.580

High

1063159

VA0D2
V-type proton ATPase subunit d 2

2

0

High-throughput

0.580

High

1063178

UBL5
Ubiquitin-like protein 5

2

0

High-throughput

0.580

High

856682

RM12
Large ribosomal subunit protein bL12m

2

9

High-throughput

0.574

High

1063138

RBP1
RalA-binding protein 1

2

4

High-throughput

0.571

High

934178

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.569

High

234519

DSCAM
Cell adhesion molecule DSCAM

1

1

High-throughput

0.541

High

843679

FXR1
RNA-binding protein FXR1

1

3

High-throughput

0.541

High

149632

COPE
Coatomer subunit epsilon

1

4

High-throughput

0.536

High

363155

FINC
Fibronectin

1

4

High-throughput

0.536

High

452781

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

1063154

WDFY1
WD repeat and FYVE domain-containing protein 1

1

6

High-throughput

0.536

High

1063167

SGK3
Serine/threonine-protein kinase Sgk3

1

2

High-throughput

0.536

High

1063170

SCYL1
N-terminal kinase-like protein

1

3

High-throughput

0.536

High

1063172

ACAP3
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

1

10

High-throughput

0.536

High

1063174

TGS1
Trimethylguanosine synthase

1

3

High-throughput

0.536

High

1063181

CPVL
Probable serine carboxypeptidase CPVL

1

4

High-throughput

0.536

High

1063183

AMPB
Aminopeptidase B

1

1

High-throughput

0.536

High

1063192

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

1

High-throughput

0.536

High

1063186

PKHF2
Pleckstrin homology domain-containing family F member 2

1

5

High-throughput

0.523

High

1063137

DAZP2
DAZ-associated protein 2

1

0

High-throughput

0.518

High

151992

TOR1A
Torsin-1A

1

1

High-throughput

0.515

High

394731

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.515

High

1063201

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

High-throughput

0.515

High

434382

TPM2
Tropomyosin beta chain

1

0

High-throughput

0.513

High

1063145

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

1063165

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1063177

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

787486

MTOR
Serine/threonine-protein kinase mTOR

1

1

High-throughput

0.508

High

369627

ESR1
Estrogen receptor

1

12

Small-scale

0.501

High

725442

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.489

High

562929

STMN1
Stathmin

1

0

High-throughput

0.486

High

162755

XPO1
Exportin-1

1

12

High-throughput

0.479

High

233459

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

279557

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

322649

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

6

High-throughput

0.479

High

384863

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

397973

ISG15
Ubiquitin-like protein ISG15

1

7

Small-scale

0.479

High

521938

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

523767

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

552758

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

568093

JUND
Transcription factor JunD

1

1

High-throughput

0.479

High

569744

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

617555

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

651237

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

668696

PML
Protein PML

1

4

High-throughput

0.479

High

670031

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

684733

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

720498

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

742300

SYUA
Alpha-synuclein

1

7

Small-scale

0.479

High

749511

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

779434

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

808621

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

818063

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

903235

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

912908

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

915685

RHOB
Rho-related GTP-binding protein RhoB

1

12

High-throughput

0.479

High

944788

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.479

High

983129

UBE3A
Ubiquitin-protein ligase E3A

1

2

High-throughput

0.479

High

1026909

PAK2
Serine/threonine-protein kinase PAK 2

1

2

High-throughput

0.479

High

1035753

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1049028

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.479

High

1050196

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

1063144

VIR
Protein virilizer homolog

1

4

High-throughput

0.479

High

1063146

RHGBA
Rho GTPase-activating protein 11A

1

1

High-throughput

0.479

High

1063148

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

6

High-throughput

0.479

High

1063149

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

1063151

MOB3C
MOB kinase activator 3C

1

3

High-throughput

0.479

High

1063152

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

1063153

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1063155

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

1063158

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

1

High-throughput

0.479

High

1063161

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.479

High

1063162

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1063164

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

1063173

FMNL2
Formin-like protein 2

1

2

High-throughput

0.479

High

1063179

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

1063184

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1063189

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1063193

PD1L1
Programmed cell death 1 ligand 1

1

2

High-throughput

0.479

High

1063195

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1063200

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

High-throughput

0.479

High

1063202

SRRM2
Serine/arginine repetitive matrix protein 2

1

4

High-throughput

0.479

High

1063187

JUPI2
Jupiter microtubule associated homolog 2

1

0

High-throughput

0.460

High

354451

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

655371

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.458

High

716681

CTNA1
Catenin alpha-1

1

0

Small-scale

0.458

High

771969

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

1063139

PCBP1
Poly(rC)-binding protein 1

1

0

Small-scale

0.458

High

1063180

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.458

High

1063185

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1063168

RNF31
E3 ubiquitin-protein ligase RNF31

1

6

Small-scale

0.457

High

402027

JUN
Transcription factor Jun

1

4

High-throughput

0.445

High

497039

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.445

High

951004

RHOG
Rho-related GTP-binding protein RhoG

1

8

Small-scale

0.445

High

1057456

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1063142

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

1063169

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

1063171

CEP63
Centrosomal protein of 63 kDa

1

6

High-throughput

0.445

High

1063175

CRML
Protein cramped-like

1

0

High-throughput

0.438

High

329728

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

1063143

DCA15
DDB1- and CUL4-associated factor 15

1

3

High-throughput

0.437

High

831339

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

1063147

SFTA2
Surfactant-associated protein 2

1

0

High-throughput

0.279

Low

1063188

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.265

Low

351753

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

1063198

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024