Interactor 1: AP180 (O60641)
Clathrin coat assembly protein AP180 (91 kDa synaptosomal-associated protein) (Clathrin coat-associated protein AP180) (Phosphoprotein F1-20)
Gene: SNAP91

Interactor 2: PICAL (Q13492)
Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein)
Gene: PICALM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANTH~ANTH
Common GO terms GO:0000149 - SNARE binding
GO:0005545 - 1-phosphatidylinositol binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005905 - clathrin-coated pit
GO:0008021 - synaptic vesicle
and 6 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 907
Hs

1 652
+ Rn
+ Sc
+ Sp
+ Sc
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024