Protein: PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)

Gene: PHLP2, PHLPP2
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q6ZVD8

Gene Ontology (top 5):
GO:0001917 - photoreceptor inner segment
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

681911

AKT1
RAC-alpha serine/threonine-protein kinase

2

16

Small-scale

0.812

High

232912

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

2

20

High-throughput

0.802

High

905387

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

5

5

High-throughput

0.720

High

1172961

WDR48
WD repeat-containing protein 48

5

5

Small-scale

0.716

High

1172962

WDR20
WD repeat-containing protein 20

4

5

Small-scale

0.697

High

153932

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

3

17

Small-scale

0.686

High

408635

KPCB
Protein kinase C beta type

1

12

Small-scale

0.665

High

259292

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

3

5

Small-scale

0.662

High

296317

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

3

9

Small-scale

0.662

High

1172960

DAA11
Dynein axonemal assembly factor 11

2

19

High-throughput

0.628

High

1172965

SNX27
Sorting nexin-27

2

14

High-throughput

0.621

High

682190

AKT2
RAC-beta serine/threonine-protein kinase

1

16

Small-scale

0.618

High

1172970

AKT3
RAC-gamma serine/threonine-protein kinase

1

15

Small-scale

0.618

High

1075423

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

3

17

High-throughput

0.613

High

616717

KS6B1
Ribosomal protein S6 kinase beta-1

1

15

Small-scale

0.575

High

1172966

VAT1
Synaptic vesicle membrane protein VAT-1 homolog

2

2

High-throughput

0.567

High

714274

HSP74
Heat shock 70 kDa protein 4

1

6

High-throughput

0.536

High

760135

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.536

High

997655

DMWD
Dystrophia myotonica WD repeat-containing protein

1

7

High-throughput

0.536

High

1172964

HS105
Heat shock protein 105 kDa

1

5

High-throughput

0.536

High

1172971

SGT1
Protein SGT1 homolog

1

17

High-throughput

0.536

High

547108

EZRI
Ezrin

1

9

High-throughput

0.515

High

911421

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.515

High

660585

GRN
Progranulin

1

0

High-throughput

0.513

High

890715

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.479

High

994092

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

14

Small-scale

0.479

High

1034907

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

7

Small-scale

0.479

High

1041876

CUL3
Cullin-3

1

5

Small-scale

0.479

High

1172963

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

1

Small-scale

0.479

High

1172967

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

1172969

FANCI
Fanconi anemia group I protein

1

1

Small-scale

0.479

High

719740

RADI
Radixin

1

7

High-throughput

0.470

High

1172959

TRI46
Tripartite motif-containing protein 46

1

11

Small-scale

0.437

High

1172968

AKTIP
AKT-interacting protein

1

1

Small-scale

0.437

High


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Last updated: 15 Jul 2024