Protein: THOC3
THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45)

Gene: THOC3
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q96J01

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000445 - THO complex part of transcription export complex
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1246350

THOC2
THO complex subunit 2

6

14

Small-scale

0.947

High

1046135

DX39B
Spliceosome RNA helicase DDX39B

4

16

Small-scale

0.890

High

1202879

THOC6
THO complex subunit 6 homolog

2

19

High-throughput

0.811

High

1045273

THOC5
THO complex subunit 5 homolog

5

3

Small-scale

0.718

High

1291496

THOC1
THO complex subunit 1

4

2

High-throughput

0.699

High

1151842

THOC7
THO complex subunit 7 homolog

3

3

High-throughput

0.675

High

1201131

THOC4
THO complex subunit 4

3

7

Small-scale

0.646

High

573420

TCPA
T-complex protein 1 subunit alpha

2

20

High-throughput

0.628

High

770982

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.628

High

826822

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.628

High

843332

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.628

High

1268427

APBP2
Amyloid protein-binding protein 2

2

6

High-throughput

0.628

High

896183

UBC12
NEDD8-conjugating enzyme Ubc12

1

4

High-throughput

0.618

High

1294828

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

4

High-throughput

0.618

High

1294830

ANLN
Anillin

1

4

High-throughput

0.618

High

228368

PRKN
E3 ubiquitin-protein ligase parkin

2

15

High-throughput

0.584

High

998154

NCBP1
Nuclear cap-binding protein subunit 1

2

1

Small-scale

0.584

High

256659

CLU
Clustered mitochondria protein homolog

2

4

High-throughput

0.574

High

821360

TCPE
T-complex protein 1 subunit epsilon

2

20

High-throughput

0.574

High

943410

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.574

High

1266393

TCPW
T-complex protein 1 subunit zeta-2

2

20

High-throughput

0.574

High

370209

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

149172

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.553

High

908971

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.553

High

1146733

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.553

High

1171252

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

1120432

NCBP3
Nuclear cap-binding protein subunit 3

2

2

High-throughput

0.552

High

1294825

KLDC3
Kelch domain-containing protein 3

1

5

High-throughput

0.536

High

1294831

BCLF1
Bcl-2-associated transcription factor 1

1

9

High-throughput

0.536

High

890800

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

High-throughput

0.501

High

942368

DLG4
Disks large homolog 4

1

1

High-throughput

0.494

High

1239412

MLKL
Mixed lineage kinase domain-like protein

1

1

High-throughput

0.494

High

813675

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.489

High

1294824

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.489

High

749777

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.481

High

233586

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

262547

TULP3
Tubby-related protein 3

1

1

High-throughput

0.479

High

326750

SNAI1
Zinc finger protein SNAI1

1

5

High-throughput

0.479

High

347600

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

379732

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

387301

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

442402

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

8

High-throughput

0.479

High

850965

HDGF
Hepatoma-derived growth factor

1

10

High-throughput

0.479

High

917750

H4
Histone H4

1

6

High-throughput

0.479

High

935118

H31
Histone H3.1

1

8

High-throughput

0.479

High

959606

VIGLN
Vigilin

1

15

High-throughput

0.479

High

1035982

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1042285

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1201601

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.479

High

1221642

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1269364

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1271166

RBP56
TATA-binding protein-associated factor 2N

1

10

High-throughput

0.479

High

1294823

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1294827

API5
Apoptosis inhibitor 5

1

1

High-throughput

0.479

High

1294829

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1294832

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

298722

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.437

High

374702

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.437

High

1261395

NUDC2
NudC domain-containing protein 2

1

14

High-throughput

0.437

High

1294833

UBQL2
Ubiquilin-2

1

2

High-throughput

0.437

High

1047210

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.407

High

1124591

ODFP2
Outer dense fiber protein 2

1

13

High-throughput

0.407

High

1130452

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.407

High

1243472

KLDC9
Kelch domain-containing protein 9

2

0

High-throughput

0.328

High

1138852

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.269

Low

378756

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

1243885

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1294826

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024