Protein: ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (hIscA)

Gene: ISCA1
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9BUE6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
GO:0016226 - iron-sulfur cluster assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1198954

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

2

6

Small-scale

0.799

High

469825

RB40L
Ras-related protein Rab-40A-like

3

3

High-throughput

0.667

High

862269

NUDT6
Nucleoside diphosphate-linked moiety X motif 6

3

1

High-throughput

0.667

High

1310109

LZTS2
Leucine zipper putative tumor suppressor 2

3

1

High-throughput

0.667

High

1298384

AP4AT
AP-4 complex accessory subunit Tepsin

3

1

Small-scale

0.662

High

1309811

HSPB9
Heat shock protein beta-9

3

0

High-throughput

0.638

High

834921

RGS3
Regulator of G-protein signaling 3

2

1

High-throughput

0.628

High

1020899

TRAF2
TNF receptor-associated factor 2

2

1

High-throughput

0.628

High

1266263

TRIB2
Tribbles homolog 2

2

2

High-throughput

0.628

High

1301577

TRIB1
Tribbles homolog 1

2

3

High-throughput

0.628

High

1273119

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

2

1

High-throughput

0.611

High

351783

SOM2
Growth hormone variant

3

2

High-throughput

0.609

High

1017281

RB40B
Ras-related protein Rab-40B

3

3

High-throughput

0.609

High

1263841

RB40A
Ras-related protein Rab-40A

3

3

High-throughput

0.609

High

1044806

RIN1
Ras and Rab interactor 1

2

0

High-throughput

0.602

High

1067810

PDIA6
Protein disulfide-isomerase A6

2

0

High-throughput

0.585

High

483637

CSH2
Chorionic somatomammotropin hormone 2

2

2

High-throughput

0.584

High

483618

CSH1
Chorionic somatomammotropin hormone 1

2

2

High-throughput

0.552

High

855721

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.536

High

1121863

BOLA3
BolA-like protein 3

1

1

High-throughput

0.536

High

1133188

CAF17
Putative transferase CAF17, mitochondrial

1

5

High-throughput

0.536

High

1165213

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

1

High-throughput

0.536

High

1223443

THNS1
Threonine synthase-like 1

1

1

High-throughput

0.536

High

1312779

TBD2A
TBC1 domain family member 2A

1

1

High-throughput

0.536

High

1312785

KIF15
Kinesin-like protein KIF15

1

1

High-throughput

0.536

High

1312787

KLH42
Kelch-like protein 42

1

1

High-throughput

0.536

High

157236

BACH1
Transcription regulator protein BACH1

1

0

High-throughput

0.513

High

167275

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.513

High

315758

SC24B
Protein transport protein Sec24B

1

0

High-throughput

0.513

High

316350

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

High-throughput

0.513

High

526442

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

0

High-throughput

0.513

High

538013

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.513

High

539846

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.513

High

664262

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.513

High

970442

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1027775

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.513

High

1051068

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

1118350

GRAP1
GRIP1-associated protein 1

1

0

High-throughput

0.513

High

1121431

P5CR3
Pyrroline-5-carboxylate reductase 3

1

0

High-throughput

0.513

High

1162009

SPSB3
SPRY domain-containing SOCS box protein 3

1

0

High-throughput

0.513

High

1162053

TRI65
E3 ubiquitin-protein ligase TRIM65

1

0

High-throughput

0.513

High

1200092

NLRX1
NLR family member X1

1

0

High-throughput

0.513

High

1202905

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.513

High

1205672

DLP1
All trans-polyprenyl-diphosphate synthase PDSS2

1

0

High-throughput

0.513

High

1218958

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1221069

BAP18
Chromatin complexes subunit BAP18

1

0

High-throughput

0.513

High

1244335

FAD1
FAD synthase

1

0

High-throughput

0.513

High

1263118

IL1FA
Interleukin-1 family member 10

1

0

High-throughput

0.513

High

1274374

TATD2
Putative deoxyribonuclease TATDN2

1

0

High-throughput

0.513

High

1291913

DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like

1

0

High-throughput

0.513

High

1300038

TPPC9
Trafficking protein particle complex subunit 9

1

0

High-throughput

0.513

High

1309698

NUD12
NAD-capped RNA hydrolase NUDT12

1

0

High-throughput

0.513

High

1309759

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.513

High

1312777

SELO
Protein adenylyltransferase SelO, mitochondrial

1

0

High-throughput

0.513

High

1312778

TGT
Queuine tRNA-ribosyltransferase catalytic subunit 1

1

0

High-throughput

0.513

High

1312780

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

0

High-throughput

0.513

High

1312783

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.513

High

1312784

ANLN
Anillin

1

0

High-throughput

0.513

High

1312786

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.513

High

1312789

NLK
Serine/threonine-protein kinase NLK

1

0

High-throughput

0.513

High

1312790

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.513

High

1312791

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

0

High-throughput

0.513

High

1312792

TPPC4
Trafficking protein particle complex subunit 4

1

0

High-throughput

0.513

High

1312793

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1129845

H2B2F
Histone H2B type 2-F

1

0

High-throughput

0.493

High

296840

KBTBB
Kelch repeat and BTB domain-containing protein 11

1

1

High-throughput

0.489

High

1301657

RB40C
Ras-related protein Rab-40C

1

3

High-throughput

0.489

High

483342

TPC2B
Trafficking protein particle complex subunit 2B

1

0

High-throughput

0.458

High

1042431

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1068065

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1152952

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1282811

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

1292434

PLPR2
Phospholipid phosphatase-related protein type 2

3

0

High-throughput

0.347

High

1312776

WDR18
WD repeat-containing protein 18

3

0

High-throughput

0.347

High

328164

SG1D1
Secretoglobin family 1D member 1

2

0

High-throughput

0.328

High

1093517

LRC36
Leucine-rich repeat-containing protein 36

2

0

High-throughput

0.328

High

1312781

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.328

High

1312782

ZMAT3
Zinc finger matrin-type protein 3

2

0

High-throughput

0.318

High

914672

ERR3
Estrogen-related receptor gamma

1

0

High-throughput

0.279

Low

1190924

TAFA3
Chemokine-like protein TAFA-3

1

0

High-throughput

0.279

Low

1205326

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.279

Low

1242888

CHDH
Choline dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1261747

TPC14
Trafficking protein particle complex subunit 14

1

0

High-throughput

0.279

Low

1299852

LENG8
Leukocyte receptor cluster member 8

1

0

High-throughput

0.279

Low

1301652

MTL26
Methyltransferase-like 26

1

0

High-throughput

0.279

Low

1312788

ORC3
Origin recognition complex subunit 3

1

0

High-throughput

0.279

Low

881270

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low

1203830

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024