Protein: PPM1K
Protein phosphatase Mn(2+)-dependent 1K (EC 3.1.3.16) (Branched-chain alpha-ketoacid dehydrogenase phosphatase) (BCKDH) (BDP) (EC 3.1.3.52) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C family member) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) ([3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase, mitochondrial)

Gene: PPM1K
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q8N3J5

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1036296

BIRC2
Baculoviral IAP repeat-containing protein 2

4

1

High-throughput

0.904

High

957734

XIAP
E3 ubiquitin-protein ligase XIAP

2

1

High-throughput

0.783

High

826314

CDK8
Cyclin-dependent kinase 8

1

8

High-throughput

0.691

High

506006

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

5

0

High-throughput

0.688

High

520724

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

5

0

High-throughput

0.688

High

602407

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

5

0

High-throughput

0.688

High

1232401

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

3

High-throughput

0.618

High

796307

MAGAB
Melanoma-associated antigen 11

2

2

High-throughput

0.606

High

253096

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1132526

UBX11
UBX domain-containing protein 11

2

0

High-throughput

0.580

High

1201499

ZN410
Zinc finger protein 410

2

0

High-throughput

0.580

High

1232404

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

486811

MYB
Transcriptional activator Myb

1

2

High-throughput

0.541

High

1232402

ENAH
Protein enabled homolog

1

2

High-throughput

0.536

High

229700

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

0

High-throughput

0.513

High

1080877

HSPB2
Heat shock protein beta-2

1

1

High-throughput

0.508

High

601946

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.494

High

1031152

PTK7
Inactive tyrosine-protein kinase 7

1

7

High-throughput

0.494

High

1168387

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

1219428

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

334243

LDHA
L-lactate dehydrogenase A chain

1

0

High-throughput

0.493

High

157353

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

2

High-throughput

0.479

High

264959

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

539822

IDE
Insulin-degrading enzyme

1

3

High-throughput

0.479

High

1014422

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

1127397

PREP
Presequence protease, mitochondrial

1

3

High-throughput

0.479

High

1232405

MY15B
Unconventional myosin-XVB

1

2

High-throughput

0.470

High

258485

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

607691

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.458

High

990171

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1232403

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1232406

RM13
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.458

High


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Last updated: 15 Jul 2024