Protein: BCAR3
Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B)

Gene: BCAR3
Organism: Homo sapiens
Interactions: 100
UniProt ID: O75815

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0002089 - lens morphogenesis in camera-type eye
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

275559

BCAR1
Breast cancer anti-estrogen resistance protein 1

5

20

Small-scale

0.937

High

275570

CASL
Enhancer of filamentation 1

4

20

Small-scale

0.910

High

275537

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

High-throughput

0.778

High

275521

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.755

High

275551

CRK
Adapter molecule crk

2

20

High-throughput

0.737

High

275527

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

275529

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

275523

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

275573

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

275544

IRS1
Insulin receptor substrate 1

2

20

High-throughput

0.634

High

275520

ABL1
Tyrosine-protein kinase ABL1

1

20

High-throughput

0.618

High

275550

ABL2
Tyrosine-protein kinase ABL2

1

20

High-throughput

0.618

High

275582

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

275592

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.618

High

275560

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

20

High-throughput

0.606

High

275577

CCD57
Coiled-coil domain-containing protein 57

2

17

High-throughput

0.606

High

275599

AP1M1
AP-1 complex subunit mu-1

2

4

High-throughput

0.606

High

275522

GAST
Gastrin [Cleaved into: Gastrin-71

2

0

High-throughput

0.602

High

275545

FUS
RNA-binding protein FUS

2

8

High-throughput

0.601

High

275515

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

20

High-throughput

0.590

High

275518

DRC4
Dynein regulatory complex subunit 4

2

1

High-throughput

0.553

High

275532

CCL5
C-C motif chemokine 5

1

2

High-throughput

0.541

High

275546

SPB5
Serpin B5

1

12

High-throughput

0.541

High

275556

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.541

High

275597

MTA3
Metastasis-associated protein MTA3

1

3

High-throughput

0.541

High

275600

BEX2
Protein BEX2

1

2

High-throughput

0.541

High

275603

BEX1
Protein BEX1

1

2

High-throughput

0.541

High

275605

VPS45
Vacuolar protein sorting-associated protein 45

1

3

High-throughput

0.541

High

275609

ERRFI
ERBB receptor feedback inhibitor 1

1

20

High-throughput

0.541

High

275569

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.536

High

275589

MY18A
Unconventional myosin-XVIIIa

1

18

High-throughput

0.536

High

275604

PCDBG
Protocadherin beta-16

1

11

High-throughput

0.536

High

275516

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.518

High

275578

GREB1
Protein GREB1

1

0

High-throughput

0.518

High

275588

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.518

High

275530

PABP1
Polyadenylate-binding protein 1

1

7

High-throughput

0.515

High

275531

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.515

High

275534

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

275598

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

275606

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

275524

A4
Amyloid-beta precursor protein

1

13

High-throughput

0.501

High

275528

HXC6
Homeobox protein Hox-C6

1

8

High-throughput

0.494

High

275576

CYTM
Cystatin-M

1

2

High-throughput

0.494

High

275581

ATAD2
ATPase family AAA domain-containing protein 2

1

3

High-throughput

0.494

High

275587

AGR3
Anterior gradient protein 3

1

4

High-throughput

0.494

High

275594

PDLI2
PDZ and LIM domain protein 2

1

20

High-throughput

0.494

High

275595

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

1

High-throughput

0.494

High

275601

NSD3
Histone-lysine N-methyltransferase NSD3

1

15

High-throughput

0.494

High

275602

PRD14
PR domain zinc finger protein 14

1

3

High-throughput

0.494

High

275585

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

5

High-throughput

0.489

High

275526

ANXA2
Annexin A2

1

10

High-throughput

0.479

High

275533

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

4

High-throughput

0.479

High

275536

LMNB1
Lamin-B1

1

20

High-throughput

0.479

High

275539

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.479

High

275541

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.479

High

275542

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

2

High-throughput

0.479

High

275543

KINH
Kinesin-1 heavy chain

1

3

High-throughput

0.479

High

275547

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

275548

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.479

High

275549

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.479

High

275552

PAXI
Paxillin

1

20

High-throughput

0.479

High

275553

NASP
Nuclear autoantigenic sperm protein

1

2

High-throughput

0.479

High

275555

TMEDA
Transmembrane emp24 domain-containing protein 10

1

1

High-throughput

0.479

High

275557

ACLY
ATP-citrate synthase

1

2

High-throughput

0.479

High

275558

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

275561

ARP2
Actin-related protein 2

1

13

High-throughput

0.479

High

275563

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

275564

SET
Protein SET

1

2

High-throughput

0.479

High

275567

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.479

High

275572

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.479

High

275574

PCBP1
Poly(rC)-binding protein 1

1

19

High-throughput

0.479

High

275575

TSN
Translin

1

2

High-throughput

0.479

High

275579

Q5T081
Regulator of chromosome condensation

1

2

High-throughput

0.479

High

275586

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

275591

FUBP2
Far upstream element-binding protein 2

1

20

High-throughput

0.479

High

275596

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

High-throughput

0.479

High

275611

RUVB1
RuvB-like 1

1

5

High-throughput

0.479

High

275540

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

2

High-throughput

0.470

High

166391

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

275535

PYRG1
CTP synthase 1

1

0

High-throughput

0.458

High

275562

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.458

High

275566

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.458

High

275612

NOSIP
Nitric oxide synthase-interacting protein

1

0

High-throughput

0.458

High

275517

RTN3
Reticulon-3

1

3

High-throughput

0.437

High

275519

AATM
Aspartate aminotransferase, mitochondrial

1

1

High-throughput

0.437

High

275525

TPM3
Tropomyosin alpha-3 chain

1

5

High-throughput

0.437

High

275538

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.437

High

275568

TIF1B
Transcription intermediary factor 1-beta

1

14

High-throughput

0.437

High

275571

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

275610

OSGI1
Oxidative stress-induced growth inhibitor 1

3

0

High-throughput

0.348

High

275565

DEF5
Defensin alpha 5

2

0

High-throughput

0.328

High

275583

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.282

High

275590

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.282

High

275593

ESIP1
Epithelial-stromal interaction protein 1

1

0

High-throughput

0.282

High

275607

HOP2
Homologous-pairing protein 2 homolog

1

0

High-throughput

0.282

High

275608

DKK3
Dickkopf-related protein 3

1

0

High-throughput

0.282

High

275554

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.279

Low

275584

CCD25
Coiled-coil domain-containing protein 25

1

0

High-throughput

0.279

Low

275580

TET2
Methylcytosine dioxygenase TET2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024