Protein: DEN6A
Protein DENND6A (DENN domain-containing protein 6A)

Gene: DEN6A, DENND6A
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q8IWF6

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043231 - intracellular membrane-bounded organelle
GO:0055037 - recycling endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

740009

TGFR2
TGF-beta receptor type-2

3

1

High-throughput

0.667

High

536396

GLU2B
Glucosidase 2 subunit beta

3

0

High-throughput

0.638

High

1168518

RN19B
E3 ubiquitin-protein ligase RNF19B

2

1

High-throughput

0.628

High

946043

DLK1
Protein delta homolog 1

2

1

High-throughput

0.611

High

856550

EFNB2
Ephrin-B2

3

2

High-throughput

0.609

High

1218649

KS6C1
Ribosomal protein S6 kinase delta-1

3

2

High-throughput

0.604

High

1218647

TPC2
Two pore channel protein 2

2

0

High-throughput

0.602

High

243487

DNJA2
DnaJ homolog subfamily A member 2

2

0

High-throughput

0.585

High

1078247

EFNB3
Ephrin-B3

2

2

High-throughput

0.574

High

957883

EFNB1
Ephrin-B1

1

2

High-throughput

0.536

High

1044923

AVR2B
Activin receptor type-2B

1

1

High-throughput

0.536

High

675839

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

986818

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1069414

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1104130

EMAL3
Echinoderm microtubule-associated protein-like 3

1

0

High-throughput

0.513

High

1218644

DEN6B
Protein DENND6B

1

0

High-throughput

0.513

High

1218653

RABE2
Rab GTPase-binding effector protein 2

1

0

High-throughput

0.513

High

507111

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

508090

FGFR1
Fibroblast growth factor receptor 1

1

2

High-throughput

0.479

High

527593

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

842007

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

1

High-throughput

0.479

High

845589

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.479

High

872672

EPHA4
Ephrin type-A receptor 4

1

1

High-throughput

0.479

High

894193

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

895162

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

914194

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

1048616

DSG2
Desmoglein-2

1

1

High-throughput

0.479

High

1052096

MAP7
Ensconsin

1

1

High-throughput

0.479

High

1079940

RB11B
Ras-related protein Rab-11B

1

2

High-throughput

0.479

High

1110015

AR13B
ADP-ribosylation factor-like protein 13B

1

1

High-throughput

0.479

High

1218642

LMTK2
Serine/threonine-protein kinase LMTK2

1

3

High-throughput

0.479

High

1218645

NBEA
Neurobeachin

1

1

High-throughput

0.479

High

1218652

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1218654

PKHA5
Pleckstrin homology domain-containing family A member 5

1

1

High-throughput

0.479

High

1218660

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

178645

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

295001

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

296942

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

475093

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

670103

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

974106

DYST
Dystonin

1

0

High-throughput

0.458

High

997186

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

0

High-throughput

0.458

High

1113803

GRDN
Girdin

1

0

High-throughput

0.458

High

1117423

TB10B
TBC1 domain family member 10B

1

0

High-throughput

0.458

High

1140595

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1151950

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1188283

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1218650

RFIP5
Rab11 family-interacting protein 5

1

0

High-throughput

0.458

High

1218656

RELCH
RAB11-binding protein RELCH

1

0

High-throughput

0.458

High

1218657

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

0

High-throughput

0.458

High

1218659

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.458

High

1218662

WDR7
WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1218663

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

0

High-throughput

0.458

High

564603

RHOQ
Rho-related GTP-binding protein RhoQ

1

2

High-throughput

0.437

High

665281

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.437

High

844606

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.437

High

971033

DSC2
Desmocollin-2

1

1

High-throughput

0.437

High

1218643

ARL10
ADP-ribosylation factor-like protein 10

1

1

High-throughput

0.437

High

1218651

RHOJ
Rho-related GTP-binding protein RhoJ

1

2

High-throughput

0.437

High

1182895

BT2A1
Butyrophilin subfamily 2 member A1

3

0

High-throughput

0.347

High

1218655

SACA1
Sperm acrosome membrane-associated protein 1

3

0

High-throughput

0.347

High

1218661

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

0

High-throughput

0.347

High

778581

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.328

High

1067919

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.328

High

1218648

HAVR2
Hepatitis A virus cellular receptor 2

2

0

High-throughput

0.328

High

179223

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

224983

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

380126

MAS
Proto-oncogene Mas

1

0

High-throughput

0.279

Low

560076

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

943986

X3CL1
Fractalkine

1

0

High-throughput

0.279

Low

1139957

SPRY7
SPRY domain-containing protein 7

1

0

High-throughput

0.279

Low

1218646

CADM4
Cell adhesion molecule 4

1

0

High-throughput

0.279

Low

1218658

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

168422

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.249

Low

205635

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

651627

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

917551

H4
Histone H4

1

0

High-throughput

0.249

Low

934953

H31
Histone H3.1

1

0

High-throughput

0.249

Low

1048444

LRP8
Low-density lipoprotein receptor-related protein 8

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024