Protein: CCL5
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]

Gene: CCL5
Organism: Homo sapiens
Interactions: 77
UniProt ID: P13501

Gene Ontology (top 5):
GO:0002407 - dendritic cell chemotaxis
GO:0002548 - monocyte chemotaxis
GO:0002676 - regulation of chronic inflammatory response
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0004672 - protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

562874

CCR1
C-C chemokine receptor type 1

9

20

Small-scale

0.968

High

562884

CCR5
C-C chemokine receptor type 5

9

20

Small-scale

0.963

High

562859

CCL5
C-C motif chemokine 5

4

19

Small-scale

0.906

High

562882

CCR3
C-C chemokine receptor type 3

4

20

Small-scale

0.888

High

390357

PLF4
Platelet factor 4

1

20

High-throughput

0.730

High

562879

SDF1
Stromal cell-derived factor 1

1

8

High-throughput

0.730

High

562903

CCL17
C-C motif chemokine 17

1

19

High-throughput

0.730

High

141814

ACKR2
Atypical chemokine receptor 2

1

20

Small-scale

0.724

High

562860

CSPG2
Versican core protein

1

10

Small-scale

0.724

High

124863

CCL24
C-C motif chemokine 24

1

18

High-throughput

0.716

High

141743

CCL21
C-C motif chemokine 21

1

18

High-throughput

0.716

High

158930

CXL11
C-X-C motif chemokine 11

1

20

High-throughput

0.716

High

190734

CCL25
C-C motif chemokine 25

1

1

High-throughput

0.716

High

191473

CCL16
C-C motif chemokine 16

1

19

High-throughput

0.716

High

343133

CXL14
C-X-C motif chemokine 14

1

6

High-throughput

0.716

High

390315

CXCL7
Platelet basic protein

1

20

High-throughput

0.716

High

390380

CXL10
C-X-C motif chemokine 10

1

20

High-throughput

0.716

High

562827

CCL2
C-C motif chemokine 2

1

18

High-throughput

0.716

High

562867

CXCL2
C-X-C motif chemokine 2

1

20

High-throughput

0.716

High

562878

XCL1
Lymphotactin

1

19

High-throughput

0.716

High

562881

CCL11
Eotaxin

1

19

High-throughput

0.716

High

562886

CCL20
C-C motif chemokine 20

1

19

High-throughput

0.716

High

562888

CXCL6
C-X-C motif chemokine 6

1

20

High-throughput

0.716

High

562893

CXCL9
C-X-C motif chemokine 9

1

20

High-throughput

0.716

High

562906

CCL13
C-C motif chemokine 13

1

18

High-throughput

0.716

High

562909

CCL28
C-C motif chemokine 28

1

9

High-throughput

0.716

High

562910

XCL2
Cytokine SCM-1 beta

1

19

High-throughput

0.716

High

562912

CCL26
C-C motif chemokine 26

1

19

High-throughput

0.716

High

562913

CCL27
C-C motif chemokine 27

1

9

High-throughput

0.692

High

562891

TF65
Transcription factor p65

4

20

Small-scale

0.688

High

518755

IL8
Interleukin-8

1

20

Small-scale

0.647

High

562883

CCR4
C-C chemokine receptor type 4

1

20

Small-scale

0.647

High

562887

CCL8
C-C motif chemokine 8

1

18

High-throughput

0.647

High

562894

IRF3
Interferon regulatory factor 3

3

10

Small-scale

0.640

High

562896

ACKR1
Atypical chemokine receptor 1

3

20

Small-scale

0.640

High

501797

CO4A
Complement C4-A

2

2

High-throughput

0.628

High

562900

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

2

1

High-throughput

0.628

High

562901

SPT20
Spermatogenesis-associated protein 20

2

1

High-throughput

0.628

High

562875

CXCR5
C-X-C chemokine receptor type 5

1

20

Small-scale

0.618

High

562880

CXCR3
C-X-C chemokine receptor type 3

1

20

Small-scale

0.618

High

562889

TSG6
Tumor necrosis factor-inducible gene 6 protein

2

15

Small-scale

0.602

High

562870

KAD4
Adenylate kinase 4, mitochondrial

2

0

High-throughput

0.602

High

562908

NTM1A
N-terminal Xaa-Pro-Lys N-methyltransferase 1

2

0

High-throughput

0.602

High

378947

PIGR
Polymeric immunoglobulin receptor

1

0

Small-scale

0.586

High

562898

CXL17
C-X-C motif chemokine 17

1

10

High-throughput

0.554

High

294820

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

3

High-throughput

0.541

High

354892

CHK2
Serine/threonine-protein kinase Chk2

1

1

High-throughput

0.541

High

376690

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

3

High-throughput

0.541

High

562864

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.541

High

562866

WT1
Wilms tumor protein

1

1

High-throughput

0.541

High

336618

BAG4
BAG family molecular chaperone regulator 4

1

0

High-throughput

0.518

High

375134

RASK
GTPase KRas

1

0

High-throughput

0.518

High

562869

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

562876

PHB1
Prohibitin 1

1

0

High-throughput

0.518

High

533864

IRF1
Interferon regulatory factor 1

1

10

Small-scale

0.515

High

562905

S10AD
Protein S100-A13

1

0

High-throughput

0.513

High

562902

SPRY4
SPRY domain-containing protein 4

1

2

High-throughput

0.489

High

562877

RAGP1
Ran GTPase-activating protein 1

1

1

High-throughput

0.481

High

562895

TRIP6
Thyroid receptor-interacting protein 6

1

1

High-throughput

0.481

High

562861

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

10

Small-scale

0.479

High

562863

CEBPB
CCAAT/enhancer-binding protein beta

1

5

Small-scale

0.479

High

562872

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

4

Small-scale

0.479

High

562890

RELB
Transcription factor RelB

1

20

Small-scale

0.479

High

562892

REL
Proto-oncogene c-Rel

1

20

Small-scale

0.479

High

562904

IRF7
Interferon regulatory factor 7

1

10

Small-scale

0.479

High

562897

EDC4
Enhancer of mRNA-decapping protein 4

1

0

High-throughput

0.460

High

562871

DPP4
Dipeptidyl peptidase 4

1

3

Small-scale

0.445

High

562911

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.439

High

555844

CADH1
Cadherin-1

1

0

High-throughput

0.438

High

562862

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

Small-scale

0.437

High

562865

SDC1
Syndecan-1

1

1

Small-scale

0.437

High

562873

SDC4
Syndecan-4

1

1

Small-scale

0.437

High

562885

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

2

High-throughput

0.437

High

562907

UBAC1
Ubiquitin-associated domain-containing protein 1

2

0

High-throughput

0.328

High

562868

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

0

High-throughput

0.282

High

562899

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025