HitPredict - High confidence protein-protein interactions

Protein: PDE8B
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)

Gene: PDE8B
Organism: Homo sapiens
Interactions: 6
UniProt ID: O95263

Gene Ontology (top 5):
GO:0001662 - behavioral fear response
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005829 - cytosol
GO:0006198 - cAMP catabolic process
GO:0008542 - visual learning

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
252952	PDE8A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	1	7	High-throughput	0.665	High
172363	XPO1 Exportin-1	1	1	High-throughput	0.479	High
332353	SNX27 Sorting nexin-27	1	4	High-throughput	0.479	High
332351	UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1	1	0	Small-scale	0.458	High
332352	FOXO1 Forkhead box protein O1	1	0	High-throughput	0.458	High
332354	NOP58 Nucleolar protein 58	1	0	High-throughput	0.458	High

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Last updated: 11Aug2025