Protein: CSK22
Casein kinase II subunit alpha' (CK II) (EC 2.7.11.1)

Gene: CSK22, CKA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 217
UniProt ID: P19454

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

584733

CSK2C
Casein kinase II subunit beta'

16

17

Small-scale

0.985

High

584757

CSK2B
Casein kinase II subunit beta

15

17

Small-scale

0.985

High

549948

CSK21
Casein kinase II subunit alpha

12

18

Small-scale

0.980

High

584651

CSK22
Casein kinase II subunit alpha'

3

17

High-throughput

0.857

High

584681

HOG1
Mitogen-activated protein kinase HOG1

3

19

Small-scale

0.855

High

584782

CDC14
Tyrosine-protein phosphatase CDC14

3

11

Small-scale

0.847

High

584659

MPIP
M-phase inducer phosphatase

2

12

Small-scale

0.799

High

584732

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

11

Small-scale

0.755

High

584687

CHD1
Chromo domain-containing protein 1

7

12

Small-scale

0.749

High

584661

SIS1
Protein SIS1

2

6

High-throughput

0.737

High

584702

SPT23
Protein SPT23

1

11

Small-scale

0.724

High

584801

FKBP4
FK506-binding protein 4

2

12

High-throughput

0.712

High

356237

H4
Histone H4

5

5

Small-scale

0.704

High

584768

UTP22
U3 small nucleolar RNA-associated protein 22

4

1

High-throughput

0.694

High

526185

KIN2
Serine/threonine-protein kinase KIN2

1

7

High-throughput

0.691

High

584674

HRR25
Casein kinase I homolog HRR25

1

9

High-throughput

0.691

High

584689

SWE1
Mitosis inhibitor protein kinase SWE1

1

20

High-throughput

0.691

High

584715

AKL1
Serine/threonine-protein kinase AKL1

1

19

High-throughput

0.691

High

584736

SAK1
SNF1-activating kinase 1

1

13

High-throughput

0.691

High

584748

FKH1
Fork head protein homolog 1

1

4

High-throughput

0.691

High

584783

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

20

High-throughput

0.691

High

584790

PKH1
Serine/threonine-protein kinase PKH1

1

20

High-throughput

0.691

High

584812

HRK1
Serine/threonine-protein kinase HRK1

1

19

High-throughput

0.691

High

584816

RTK1
Probable serine/threonine-protein kinase RTK1

1

19

High-throughput

0.691

High

584788

HOT1
High-osmolarity-induced transcription protein 1

4

1

Small-scale

0.691

High

584738

IFH1
Protein IFH1

4

10

Small-scale

0.690

High

584684

SPT16
FACT complex subunit SPT16

10

5

Small-scale

0.689

High

584758

FIP1
Pre-mRNA polyadenylation factor FIP1

4

4

Small-scale

0.688

High

584777

H3
Histone H3

4

9

Small-scale

0.683

High

584658

SPT6
Transcription elongation factor SPT6

3

7

Small-scale

0.678

High

584821

RIO1
Serine/threonine-protein kinase RIO1

3

6

Small-scale

0.674

High

584710

ELF1
Transcription elongation factor 1

3

1

Small-scale

0.671

High

584798

SVF1
Ceramide-binding protein SVF1

3

1

Small-scale

0.670

High

584820

PSH1
RING finger protein PSH1

3

6

Small-scale

0.664

High

584779

RHO3
GTP-binding protein RHO3

1

4

High-throughput

0.656

High

584711

CAB3
Coenzyme A biosynthesis protein 3

5

4

High-throughput

0.651

High

584708

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

3

4

High-throughput

0.647

High

409882

CDC37
Hsp90 co-chaperone Cdc37

1

6

Small-scale

0.647

High

584694

MSN2
Zinc finger protein MSN2

1

12

Small-scale

0.647

High

584695

MSN4
Zinc finger protein MSN4

1

14

Small-scale

0.647

High

584793

POB3
FACT complex subunit POB3

5

4

Small-scale

0.645

High

392282

H2A2
Histone H2A.2

3

10

High-throughput

0.643

High

584705

BDF1
Bromodomain-containing factor 1

3

20

Small-scale

0.640

High

420548

SPT2
Protein SPT2

2

1

Small-scale

0.639

High

584751

SA185
SIT4-associating protein SAP185

2

8

High-throughput

0.628

High

584769

PESC
Pescadillo homolog

2

3

High-throughput

0.628

High

584701

CENPC
Inner kinetochore subunit MIF2

2

1

Small-scale

0.625

High

584656

SIN3
Transcriptional regulatory protein SIN3

2

3

High-throughput

0.621

High

584778

CTR9
RNA polymerase-associated protein CTR9

2

12

High-throughput

0.621

High

584805

CDC73
Cell division control protein 73

2

1

High-throughput

0.621

High

584741

BEM2
GTPase-activating protein BEM2/IPL2

1

17

High-throughput

0.618

High

408266

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

9

High-throughput

0.618

High

456987

SWI6
Regulatory protein SWI6

1

13

High-throughput

0.618

High

584683

ZUO1
Zuotin

1

4

High-throughput

0.618

High

584723

RCK2
Serine/threonine-protein kinase RCK2

1

20

High-throughput

0.618

High

416191

SIR2
NAD-dependent histone deacetylase SIR2

2

11

Small-scale

0.611

High

420080

TOP2
DNA topoisomerase 2

2

4

High-throughput

0.611

High

501153

HSF
Heat shock transcription factor

2

8

Small-scale

0.602

High

490289

HSP71
Heat shock protein SSA1

2

14

High-throughput

0.601

High

510209

SSB1
Ribosome-associated molecular chaperone SSB1

2

14

High-throughput

0.601

High

584686

PP12
Serine/threonine-protein phosphatase PP1-2

2

15

High-throughput

0.601

High

584743

SSB2
Ribosome-associated molecular chaperone SSB2

2

14

High-throughput

0.601

High

584680

ASF1
Histone chaperone ASF1

2

1

High-throughput

0.588

High

584749

ULP2
Ubiquitin-like-specific protease 2

2

3

High-throughput

0.586

High

541611

SEC63
Protein translocation protein SEC63

1

5

Small-scale

0.579

High

584752

MAF1
Repressor of RNA polymerase III transcription MAF1

1

3

Small-scale

0.578

High

584766

LIF1
Ligase-interacting factor 1

2

0

Small-scale

0.576

High

365762

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

584665

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.575

High

355338

H2B1
Histone H2B.1

2

9

High-throughput

0.571

High

584671

SPT5
Transcription elongation factor SPT5

2

7

High-throughput

0.571

High

584679

SFP1
Transcription factor SFP1

2

1

Small-scale

0.571

High

584730

YHT1
PH domain-containing protein YHR131C

2

1

High-throughput

0.571

High

584745

ATAD2
ATPase histone chaperone YTA7

2

6

Small-scale

0.571

High

526943

TBP
TATA-box-binding protein

1

1

Small-scale

0.561

High

535748

ABF1
ARS-binding factor 1

1

1

Small-scale

0.561

High

584654

CLH
Clathrin heavy chain

1

4

Small-scale

0.561

High

584815

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.561

High

410072

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

11

Small-scale

0.553

High

420222

CALM
Calmodulin

1

20

Small-scale

0.553

High

584719

EIF3A
Eukaryotic translation initiation factor 3 subunit A

2

20

Small-scale

0.549

High

584706

DHR2
Probable ATP-dependent RNA helicase DHR2

1

7

High-throughput

0.541

High

584771

NOP19
Nucleolar protein 19

1

1

High-throughput

0.541

High

584735

SEC31
Protein transport protein SEC31

2

17

High-throughput

0.537

High

501313

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

10

High-throughput

0.536

High

502951

SEC7
Protein transport protein SEC7

1

4

High-throughput

0.536

High

584675

XPO1
Exportin-1

1

9

High-throughput

0.536

High

584698

SPT7
Transcriptional activator SPT7

1

20

High-throughput

0.536

High

584699

RRP1
Ribosomal RNA-processing protein 1

1

5

High-throughput

0.536

High

584716

TAF5
Transcription initiation factor TFIID subunit 5

1

17

High-throughput

0.536

High

584720

TTL
Probable tubulin--tyrosine ligase PBY1

1

4

High-throughput

0.536

High

584728

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.536

High

584744

RIO2
Serine/threonine-protein kinase RIO2

1

6

High-throughput

0.536

High

584746

UTP18
U3 small nucleolar RNA-associated protein 18

1

2

High-throughput

0.536

High

584760

NET1
Nucleolar protein NET1

1

3

High-throughput

0.536

High

584765

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

7

High-throughput

0.536

High

584772

PXR1
Protein PXR1

1

1

High-throughput

0.536

High

584785

TOF2
Topoisomerase 1-associated factor 2

1

3

High-throughput

0.536

High

584789

GCN5
Histone acetyltransferase GCN5

1

20

High-throughput

0.536

High

584794

ERB1
Ribosome biogenesis protein ERB1

1

17

High-throughput

0.536

High

584802

ESF1
Pre-rRNA-processing protein ESF1

1

2

High-throughput

0.536

High

584808

PSR2
Probable phosphatase PSR2

1

5

High-throughput

0.536

High

584814

CTI6
Histone deacetylase complex subunit CTI6

1

5

High-throughput

0.536

High

584822

RRP36
rRNA biogenesis protein RRP36

1

1

Small-scale

0.536

High

584697

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.518

High

584721

PAF1
RNA polymerase II-associated protein 1

1

2

High-throughput

0.515

High

584774

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

4

High-throughput

0.515

High

584662

SCJ1
DnaJ-related protein SCJ1

1

5

High-throughput

0.514

High

584761

HLJ1
Protein HLJ1

1

5

High-throughput

0.514

High

584668

CSM1
Monopolin complex subunit CSM1

1

0

High-throughput

0.513

High

584696

MKS1
Negative regulator of RAS-cAMP pathway

1

0

High-throughput

0.513

High

584813

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.513

High

584691

SLA2
Protein SLA2

1

20

Small-scale

0.512

High

584764

TOM22
Mitochondrial import receptor subunit TOM22

1

1

Small-scale

0.512

High

357454

RLA4
Large ribosomal subunit protein P2B

1

2

Small-scale

0.501

High

425290

PHO4
Phosphate system positive regulatory protein PHO4

1

1

Small-scale

0.501

High

539438

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

10

Small-scale

0.501

High

584653

OPI1
Transcriptional repressor OPI1

1

1

Small-scale

0.501

High

584672

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

11

High-throughput

0.501

High

584682

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

1

Small-scale

0.501

High

584685

PAH1
Phosphatidic acid phosphohydrolase 1

1

4

Small-scale

0.501

High

584722

IF5
Eukaryotic translation initiation factor 5

1

8

Small-scale

0.501

High

584724

SIC1
Protein SIC1

1

1

Small-scale

0.501

High

584787

NRG1
Transcriptional regulator NRG1

1

11

Small-scale

0.501

High

584792

PUF6
Pumilio homology domain family member 6

1

6

Small-scale

0.501

High

584795

CRF1
Transcription factor CRF1

1

2

Small-scale

0.501

High

342654

ENO1
Enolase 1

1

4

High-throughput

0.500

High

378278

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.500

High

542658

TAL1
Transaldolase

1

2

High-throughput

0.500

High

584740

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.500

High

546681

SEC23
Protein transport protein SEC23

1

1

High-throughput

0.489

High

584690

DOM34
Protein DOM34

1

1

High-throughput

0.489

High

584810

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

1

4

High-throughput

0.489

High

410752

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.479

High

537351

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

584676

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.479

High

141141

RS9A
Small ribosomal subunit protein uS4A

1

5

High-throughput

0.479

High

355768

H2B2
Histone H2B.2

1

9

High-throughput

0.479

High

357871

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

392048

H2A1
Histone H2A.1

1

10

High-throughput

0.479

High

406765

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.479

High

425751

RS19A
Small ribosomal subunit protein eS19A

1

5

High-throughput

0.479

High

480467

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.479

High

482070

RS18A
Small ribosomal subunit protein uS13A

1

5

High-throughput

0.479

High

515100

TAF13
Transcription initiation factor TFIID subunit 13

1

1

Small-scale

0.479

High

584655

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

5

High-throughput

0.479

High

584660

NAP1
Nucleosome assembly protein

1

20

Small-scale

0.479

High

584663

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

584664

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.479

High

584666

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

584670

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

584673

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.479

High

584677

FUN30
ATP-dependent helicase FUN30

1

14

High-throughput

0.479

High

584678

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

584693

RS3A1
Small ribosomal subunit protein eS1A

1

7

High-throughput

0.479

High

584707

CENPA
Histone H3-like centromeric protein CSE4

1

9

High-throughput

0.479

High

584725

RS20
Small ribosomal subunit protein uS10

1

5

High-throughput

0.479

High

584737

YCFI
Metal resistance protein YCF1

1

2

Small-scale

0.479

High

584739

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

584750

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

584755

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

15

High-throughput

0.479

High

584763

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.479

High

584776

ORC1
Origin recognition complex subunit 1

1

10

High-throughput

0.479

High

584784

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

584791

DHR1
Probable ATP-dependent RNA helicase DHR1

1

5

High-throughput

0.479

High

584797

SWR1
Helicase SWR1

1

10

High-throughput

0.479

High

584800

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

584804

UTP4
U3 small nucleolar RNA-associated protein 4

1

12

Small-scale

0.479

High

584811

SGO1
Shugoshin

1

1

High-throughput

0.479

High

584818

SSF2
Ribosome biogenesis protein SSF2

1

3

High-throughput

0.479

High

584819

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

584667

MRC1
Mediator of replication checkpoint protein 1

1

0

High-throughput

0.458

High

584754

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

584700

TOM20
Mitochondrial import receptor subunit TOM20

1

1

Small-scale

0.457

High

584770

DAM1
DASH complex subunit DAM1

1

1

Small-scale

0.457

High

584809

MIM1
Mitochondrial import protein 1

1

1

Small-scale

0.457

High

584657

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.457

High

584669

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

15

High-throughput

0.457

High

584714

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

5

High-throughput

0.457

High

584727

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

2

High-throughput

0.457

High

584786

PDR12
ATP-dependent permease PDR12

1

1

High-throughput

0.457

High

584807

PSR1
Phosphatase PSR1

1

5

High-throughput

0.457

High

493160

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

584692

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

584712

SET3
SET domain-containing protein 3

1

10

High-throughput

0.445

High

584713

RPF2
Ribosome biogenesis protein RPF2

1

1

High-throughput

0.445

High

584731

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

2

High-throughput

0.445

High

584747

6P21
6-phosphofructo-2-kinase 1

1

4

High-throughput

0.445

High

584781

SEN1
Helicase SEN1

1

2

Small-scale

0.445

High

584803

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

16

High-throughput

0.445

High

584823

RLF2
Chromatin assembly factor 1 subunit p90

1

2

High-throughput

0.445

High

524156

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

584717

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

584729

NMD2
Nonsense-mediated mRNA decay protein 2

1

1

Small-scale

0.437

High

584734

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

1

Small-scale

0.437

High

584773

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

584775

NST1
Stress response protein NST1

1

20

High-throughput

0.437

High

584780

NUM1
Nuclear migration protein NUM1

1

20

High-throughput

0.437

High

584806

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

584709

MID2
Cell wall integrity sensor MID2

1

6

High-throughput

0.417

High

584767

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.417

High

584796

RTN1
Reticulon-like protein 1

1

4

High-throughput

0.417

High

584703

MNR2
Manganese resistance protein MNR2

1

1

High-throughput

0.407

High

584756

LSB3
LAS seventeen-binding protein 3

1

5

High-throughput

0.407

High

584759

STU2
Protein STU2

1

8

High-throughput

0.407

High

584799

YL407
Uncharacterized protein YLR407W

3

0

High-throughput

0.339

High

584817

ATG9
Autophagy-related protein 9

2

0

High-throughput

0.318

High

584762

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.279

Low

427344

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

0

High-throughput

0.269

Low

584742

RSM18
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.269

Low

584688

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

584652

HNM1
Choline transport protein

1

0

High-throughput

0.238

Low

584704

SFK1
Protein SFK1

1

0

High-throughput

0.238

Low

584718

RFS1
Protein RFS1

1

0

High-throughput

0.238

Low

584726

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.238

Low

584753

MDJ2
Mitochondrial DnaJ homolog 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024