Protein: SMAD7
Mothers against decapentaplegic homolog 7 (MAD homolog 7) (Mothers against DPP homolog 7) (Mothers against decapentaplegic homolog 8) (MAD homolog 8) (Mothers against DPP homolog 8) (SMAD family member 7) (SMAD 7) (Smad7)

Gene: SMAD7
Organism: Mus musculus
Interactions: 26
UniProt ID: O35253

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001650 - fibrillar center
GO:0001657 - ureteric bud development
GO:0002725 - negative regulation of T cell cytokine production
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

59022

SMUF2
E3 ubiquitin-protein ligase SMURF2

3

20

Small-scale

0.640

High

204414

SMAD6
Mothers against decapentaplegic homolog 6

1

18

Small-scale

0.618

High

204547

SMAD3
Mothers against decapentaplegic homolog 3

1

18

Small-scale

0.618

High

204543

CBLB
E3 ubiquitin-protein ligase CBL-B

1

4

Small-scale

0.561

High

204535

AXIN1
Axin-1

1

7

Small-scale

0.515

High

204549

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

Small-scale

0.515

High

148066

PAR3
Proteinase-activated receptor 3

1

3

Small-scale

0.501

High

204542

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

17

Small-scale

0.501

High

59122

PRD16
Histone-lysine N-methyltransferase PRDM16

1

13

Small-scale

0.479

High

204534

BMPR2
Bone morphogenetic protein receptor type-2

1

20

Small-scale

0.479

High

204537

AXIN2
Axin-2

1

7

Small-scale

0.479

High

204538

CO3A1

1

16

Small-scale

0.479

High

204539

CO1A1
Collagen alpha-1(I) chain

1

16

Small-scale

0.479

High

204540

BMR1A
Bone morphogenetic protein receptor type-1A

1

20

Small-scale

0.479

High

204541

ACVR1
Activin receptor type-1

1

20

Small-scale

0.479

High

204544

SF3B2
Splicing factor 3B subunit 2

1

5

Small-scale

0.479

High

204546

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

10

Small-scale

0.479

High

204548

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

1

2

Small-scale

0.479

High

204550

PEX6
Peroxisomal ATPase PEX6

1

5

Small-scale

0.479

High

204551

RN111
E3 ubiquitin-protein ligase Arkadia

1

9

Small-scale

0.479

High

204552

ZMYM2
Zinc finger MYM-type protein 2

1

5

Small-scale

0.479

High

204553

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

20

Small-scale

0.479

High

204554

4ET
Eukaryotic translation initiation factor 4E transporter

1

4

Small-scale

0.479

High

204545

ERBIN
Erbin

1

10

Small-scale

0.457

High

204555

ANM1
Protein arginine N-methyltransferase 1

1

5

Small-scale

0.445

High

204536

CO5A1

1

16

Small-scale

0.437

High


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Last updated: 11Aug2025