Protein: DCC
Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC)

Gene: DCC
Organism: Homo sapiens
Interactions: 71
UniProt ID: P43146

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0004888 - transmembrane signaling receptor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317787

NET1
Netrin-1

5

13

Small-scale

0.922

High

793638

FAK1
Focal adhesion kinase 1

3

15

Small-scale

0.874

High

647498

MK03
Mitogen-activated protein kinase 3

2

3

Small-scale

0.754

High

487205

ANDR
Androgen receptor

1

5

Small-scale

0.740

High

596373

RASA1
Ras GTPase-activating protein 1

1

6

High-throughput

0.698

High

658833

MK01
Mitogen-activated protein kinase 1

1

3

Small-scale

0.691

High

793657

TRIM9
E3 ubiquitin-protein ligase TRIM9

2

15

Small-scale

0.675

High

793651

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

0

High-throughput

0.656

High

793659

NET4
Netrin-4

1

12

Small-scale

0.647

High

793621

RL5
Large ribosomal subunit protein uL18

2

1

Small-scale

0.646

High

793626

CASP9
Caspase-9

3

1

Small-scale

0.640

High

793648

COR2A
Coronin-2A

1

1

High-throughput

0.625

High

793622

RL28
Large ribosomal subunit protein eL28

2

1

Small-scale

0.621

High

557632

NCK1
SH2/SH3 adapter protein NCK1

1

11

Small-scale

0.618

High

574509

ITB5
Integrin beta-5

1

6

Small-scale

0.618

High

793620

DCC
Netrin receptor DCC

1

20

Small-scale

0.618

High

780612

IF2G
Eukaryotic translation initiation factor 2 subunit 3

2

2

Small-scale

0.611

High

793625

EI2BB
Translation initiation factor eIF2B subunit beta

2

2

Small-scale

0.611

High

793628

EIF3E
Eukaryotic translation initiation factor 3 subunit E

2

1

Small-scale

0.611

High

793635

RL10A
Large ribosomal subunit protein uL1

2

4

Small-scale

0.611

High

793641

MAPK3
MAP kinase-activated protein kinase 3

1

1

High-throughput

0.590

High

793660

MYO10
Unconventional myosin-X

1

3

Small-scale

0.589

High

793644

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

1

Small-scale

0.586

High

416947

IF4E
Eukaryotic translation initiation factor 4E

2

2

Small-scale

0.584

High

793632

RS4X
Small ribosomal subunit protein eS4, X isoform

2

0

Small-scale

0.559

High

793652

BARD1
BRCA1-associated RING domain protein 1

1

13

High-throughput

0.555

High

793643

TRI67
Tripartite motif-containing protein 67

1

14

Small-scale

0.553

High

788158

CASP3
Caspase-3

1

1

Small-scale

0.552

High

793666

DP13A
DCC-interacting protein 13-alpha

1

3

Small-scale

0.552

High

657468

TMOD1
Tropomodulin-1

1

1

High-throughput

0.541

High

793656

TBD2A
TBC1 domain family member 2A

1

1

High-throughput

0.541

High

546965

EZRI
Ezrin

1

8

Small-scale

0.536

High

793623

RS10
Small ribosomal subunit protein eS10

1

2

Small-scale

0.536

High

793633

RL23
Large ribosomal subunit protein uL14

1

1

Small-scale

0.536

High

793637

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

6

High-throughput

0.536

High

793639

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

Small-scale

0.536

High

793645

IF4E3
Eukaryotic translation initiation factor 4E type 3

1

2

Small-scale

0.536

High

793664

LHX3
LIM/homeobox protein Lhx3

1

4

High-throughput

0.536

High

793665

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

Small-scale

0.536

High

793627

MAZ
Myc-associated zinc finger protein

1

1

Small-scale

0.523

High

393813

ALDOB
Fructose-bisphosphate aldolase B

1

0

High-throughput

0.518

High

450756

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.518

High

588852

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

Small-scale

0.513

High

596448

PHOS
Phosducin

1

0

High-throughput

0.513

High

642218

RL13
Large ribosomal subunit protein eL13

1

0

Small-scale

0.513

High

793631

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.513

High

793634

RS24
Small ribosomal subunit protein eS24

1

0

Small-scale

0.513

High

793636

RL38
Large ribosomal subunit protein eL38

1

0

Small-scale

0.513

High

793658

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

Small-scale

0.513

High

793647

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

5

High-throughput

0.494

High

363734

ALBU
Albumin

1

2

High-throughput

0.489

High

199096

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

1

Small-scale

0.481

High

773262

RL13A
Large ribosomal subunit protein uL13

1

1

Small-scale

0.479

High

793629

IF4A1
Eukaryotic initiation factor 4A-I

1

3

Small-scale

0.479

High

793630

RS23
Small ribosomal subunit protein uS12

1

1

Small-scale

0.479

High

793640

IF4A2
Eukaryotic initiation factor 4A-II

1

3

Small-scale

0.479

High

793663

RRBP1
Ribosome-binding protein 1

1

5

High-throughput

0.470

High

556803

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

793624

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

Small-scale

0.458

High

793661

EI2BG
Translation initiation factor eIF2B subunit gamma

1

0

Small-scale

0.458

High

793662

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

793655

EIF2A
Eukaryotic translation initiation factor 2A

1

1

Small-scale

0.437

High

245796

CATL2
Cathepsin L2

1

0

High-throughput

0.282

High

793642

TSTD2
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

1

0

High-throughput

0.282

High

793646

TDRD7
Tudor domain-containing protein 7

1

0

High-throughput

0.282

High

793649

SFRP2
Secreted frizzled-related protein 2

1

0

High-throughput

0.282

High

793653

TRMO
tRNA

1

0

High-throughput

0.282

High

793654

HEMGN
Hemogen

1

0

High-throughput

0.282

High

793650

REEP6
Receptor expression-enhancing protein 6

1

0

High-throughput

0.279

Low

524548

LYL1
Protein lyl-1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024