Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.936

The method score is based on:

Property Details
Experiments 17893324, 15719014, 12672817, 16636290, 17255943
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, dynamic light scattering, nuclear magnetic resonance, competition binding, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_9, PH~SH3_9, SH3_9~SH3_9
Common GO terms GO:0002102 - podosome
GO:0005829 - cytosol
GO:0043197 - dendritic spine
GO:0045296 - cadherin binding
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 550
Hs

1 1129
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024