Protein: LOXE3
Hydroperoxide isomerase ALOXE3 (Epidermis-type lipoxygenase 3) (Epidermal LOX-3) (e-LOX-3) (eLOX-3) (Hydroperoxy dehydratase ALOXE3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Hydroperoxy icosatetraenoate isomerase) (EC 5.4.4.7)

Gene: LOXE3, ALOXE3
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q9BYJ1

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0005829 - cytosol
GO:0006665 - sphingolipid metabolic process
GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019233 - sensory perception of pain

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

523134

SRC
Proto-oncogene tyrosine-protein kinase Src

2

6

High-throughput

0.628

High

1125829

HERC4
Probable E3 ubiquitin-protein ligase HERC4

2

1

High-throughput

0.628

High

259882

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

3

Small-scale

0.618

High

274696

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

3

1

High-throughput

0.609

High

1183769

DPPA4
Developmental pluripotency-associated protein 4

3

1

High-throughput

0.609

High

504704

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.602

High

1244926

NBEA
Neurobeachin

2

0

High-throughput

0.602

High

1316991

KTU
Protein kintoun

2

0

High-throughput

0.602

High

1115576

GLYR1
Cytokine-like nuclear factor N-PAC

2

0

High-throughput

0.585

High

1300524

ALPK1
Alpha-protein kinase 1

2

0

High-throughput

0.576

High

1080626

ZIC1
Zinc finger protein ZIC 1

2

2

High-throughput

0.574

High

1101594

CCD27
Coiled-coil domain-containing protein 27

2

1

High-throughput

0.574

High

632885

TYY1
Transcriptional repressor protein YY1

2

3

High-throughput

0.553

High

834922

RGS3
Regulator of G-protein signaling 3

1

1

High-throughput

0.536

High

1169186

RN111
E3 ubiquitin-protein ligase Arkadia

1

1

High-throughput

0.536

High

1203671

AROS
Active regulator of SIRT1

1

1

High-throughput

0.536

High

1316993

PLK2
Serine/threonine-protein kinase PLK2

1

3

High-throughput

0.536

High

500085

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

1316995

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

0

High-throughput

0.513

High

200843

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

1

High-throughput

0.504

High

392939

IFNA4
Interferon alpha-4

1

1

High-throughput

0.489

High

540878

PO2F1
POU domain, class 2, transcription factor 1

1

1

High-throughput

0.489

High

1024314

ZN154
Zinc finger protein 154

1

1

High-throughput

0.489

High

1203099

ZC3C1
Zinc finger C3HC-type protein 1

1

1

High-throughput

0.489

High

1204496

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

1

High-throughput

0.489

High

1316988

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

1

High-throughput

0.489

High

1316989

TB22B
TBC1 domain family member 22B

1

1

High-throughput

0.489

High

1316994

DAPLE
Protein Daple

1

2

High-throughput

0.489

High

1316996

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.489

High

1316997

RNF6
E3 ubiquitin-protein ligase RNF6

1

5

High-throughput

0.489

High

1269538

ESR2
Estrogen receptor beta

1

4

High-throughput

0.437

High

816303

GLIP1
Glioma pathogenesis-related protein 1

3

0

High-throughput

0.345

High

1199929

ZFHX4
Zinc finger homeobox protein 4

2

0

High-throughput

0.328

High

1269119

NECT2
Nectin-2

2

0

High-throughput

0.328

High

1316987

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

2

0

High-throughput

0.328

High

1161287

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.324

High

735102

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.316

High

217594

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

330589

ZBED1
E3 SUMO-protein ligase ZBED1

1

0

High-throughput

0.279

Low

1051734

RCAN2
Calcipressin-2

1

0

High-throughput

0.279

Low

1069784

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.279

Low

1125940

BEX5
Protein BEX5

1

0

High-throughput

0.279

Low

1223406

UBAD2
UBA-like domain-containing protein 2

1

0

High-throughput

0.279

Low

1224001

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1230110

F177A
Protein FAM177A1

1

0

High-throughput

0.279

Low

1274620

WNT8B
Protein Wnt-8b

1

0

High-throughput

0.279

Low

1316992

TLR7
Toll-like receptor 7

1

0

High-throughput

0.279

Low

834237

VEGFB
Vascular endothelial growth factor B

1

0

High-throughput

0.249

Low

877872

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

1287265

PKHB2
Pleckstrin homology domain-containing family B member 2

1

0

High-throughput

0.249

Low

1316990

CT096
Uncharacterized protein C20orf96

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024