HitPredict - High confidence protein-protein interactions

Protein: S12A2
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (BSC2) (Na-K-2Cl cotransporter 1) (mNKCC1)

Gene: S12A2, Slc12a2
Organism: Mus musculus
Interactions: 8
UniProt ID: P55012

Gene Ontology (top 5):
GO:0006883 - intracellular sodium ion homeostasis
GO:0006884 - cell volume homeostasis
GO:0008511 - sodium:potassium:chloride symporter activity
GO:0010818 - T cell chemotaxis
GO:0015079 - potassium ion transmembrane transporter activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
933509	STK39 STE20/SPS1-related proline-alanine-rich protein kinase	2	10	Small-scale	0.608	High
867741	MK14 Mitogen-activated protein kinase 14	1	1	Small-scale	0.500	High
205001	ADA10 Disintegrin and metalloproteinase domain-containing protein 10	1	2	High-throughput	0.479	High
933507	OXSR1 Serine/threonine-protein kinase OSR1	1	10	Small-scale	0.457	High
723299	SSR3 Somatostatin receptor type 3	1	6	High-throughput	0.437	High
933506	STING Stimulator of interferon genes protein	1	5	High-throughput	0.437	High
662953	MDM2 E3 ubiquitin-protein ligase Mdm2	1	0	Small-scale	0.249	Low
933508	SRCN1 SRC kinase signaling inhibitor 1	1	0	High-throughput	0.232	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025