Protein: ADA10
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)

Gene: ADA10, Adam10
Organism: Mus musculus
Interactions: 197
UniProt ID: O35598

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001701 - in utero embryonic development
GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

104782

TSN15
Tetraspanin-15

1

20

High-throughput

0.618

High

205002

NCAN
Neurocan core protein

1

18

High-throughput

0.618

High

205022

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

6

High-throughput

0.618

High

205093

TSN14
Tetraspanin-14

1

20

High-throughput

0.618

High

205069

DLG1
Disks large homolog 1

2

11

Small-scale

0.584

High

205047

TSN7
Tetraspanin-7

1

20

High-throughput

0.553

High

205065

HPLN4
Hyaluronan and proteoglycan link protein 4

1

6

High-throughput

0.553

High

86373

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

1

5

High-throughput

0.479

High

104435

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.479

High

104744

TPR
Nucleoprotein TPR

1

1

High-throughput

0.479

High

107177

F8VQE9
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

1

High-throughput

0.479

High

148290

DCTN1
Dynactin subunit 1

1

2

High-throughput

0.479

High

204216

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

3

High-throughput

0.479

High

204740

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

1

High-throughput

0.479

High

204975

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.479

High

204977

BSN
Protein bassoon

1

5

High-throughput

0.479

High

204979

LIN7C
Protein lin-7 homolog C

1

12

High-throughput

0.479

High

204983

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

5

High-throughput

0.479

High

204986

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.479

High

204987

EZRI
Ezrin

1

2

High-throughput

0.479

High

204988

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

5

High-throughput

0.479

High

204990

KIF5C
Kinesin heavy chain isoform 5C

1

2

High-throughput

0.479

High

204992

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

5

High-throughput

0.479

High

204996

CBR1
Carbonyl reductase [NADPH] 1

1

1

High-throughput

0.479

High

204997

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

204998

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.479

High

204999

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

205001

S12A2
Solute carrier family 12 member 2

1

2

High-throughput

0.479

High

205004

VATD
V-type proton ATPase subunit D

1

1

High-throughput

0.479

High

205005

TPM1
Tropomyosin alpha-1 chain

1

1

High-throughput

0.479

High

205006

LIPA3
Liprin-alpha-3

1

3

High-throughput

0.479

High

205008

GABT
4-aminobutyrate aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

205009

PRS8
26S proteasome regulatory subunit 8

1

1

High-throughput

0.479

High

205010

T22D1
TSC22 domain family protein 1

1

10

High-throughput

0.479

High

205011

RAB1A
Ras-related protein Rab-1A

1

2

High-throughput

0.479

High

205013

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

1

High-throughput

0.479

High

205014

MK01
Mitogen-activated protein kinase 1

1

5

High-throughput

0.479

High

205016

TIAR
Nucleolysin TIAR

1

1

High-throughput

0.479

High

205017

ROCK2
Rho-associated protein kinase 2

1

3

High-throughput

0.479

High

205018

AT8A1
Phospholipid-transporting ATPase IA

1

3

High-throughput

0.479

High

205019

WNK1
Serine/threonine-protein kinase WNK1

1

9

High-throughput

0.479

High

205021

ANXA4
Annexin A4

1

3

High-throughput

0.479

High

205023

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

205024

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

205025

ANXA7
Annexin A7

1

3

High-throughput

0.479

High

205026

STING
Stimulator of interferon genes protein

1

4

High-throughput

0.479

High

205029

WNK2
Serine/threonine-protein kinase WNK2

1

6

High-throughput

0.479

High

205030

AAK1
AP2-associated protein kinase 1

1

1

High-throughput

0.479

High

205032

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

2

High-throughput

0.479

High

205033

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

4

High-throughput

0.479

High

205037

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

2

High-throughput

0.479

High

205038

SPB6
Serpin B6

1

3

High-throughput

0.479

High

205039

CAPR1
Caprin-1

1

7

High-throughput

0.479

High

205040

CTNA2
Catenin alpha-2

1

1

High-throughput

0.479

High

205041

AP180
Clathrin coat assembly protein AP180

1

4

High-throughput

0.479

High

205043

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.479

High

205045

KINH
Kinesin-1 heavy chain

1

2

High-throughput

0.479

High

205046

DLG4
Disks large homolog 4

1

12

High-throughput

0.479

High

205049

MK03
Mitogen-activated protein kinase 3

1

5

High-throughput

0.479

High

205050

VINC
Vinculin

1

1

High-throughput

0.479

High

205053

CSKI1
Caskin-1

1

1

High-throughput

0.479

High

205054

ANM8
Protein arginine N-methyltransferase 8

1

1

High-throughput

0.479

High

205055

ERC2
ERC protein 2

1

1

High-throughput

0.479

High

205056

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

5

High-throughput

0.479

High

205057

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.479

High

205062

MAP6
Microtubule-associated protein 6

1

6

High-throughput

0.479

High

205067

NFASC
Neurofascin

1

3

High-throughput

0.479

High

205068

NRCAM
Neuronal cell adhesion molecule

1

4

High-throughput

0.479

High

205070

ERLN2
Erlin-2

1

5

High-throughput

0.479

High

205071

SYAC
Alanine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

205073

Q8BH80
Vesicle-associated membrane protein, associated protein B and C

1

1

High-throughput

0.479

High

205075

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

1

High-throughput

0.479

High

205076

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.479

High

205077

LIPA2
Liprin-alpha-2

1

3

High-throughput

0.479

High

205081

ANK2
Ankyrin-2

1

1

High-throughput

0.479

High

205084

WDR37
WD repeat-containing protein 37

1

1

High-throughput

0.479

High

205085

SYN3
Synapsin-3

1

1

High-throughput

0.479

High

205090

AHI1
Jouberin

1

3

High-throughput

0.479

High

205091

FNDC5
Fibronectin type III domain-containing protein 5

1

4

High-throughput

0.479

High

205092

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.479

High

205094

EMAL3
Echinoderm microtubule-associated protein-like 3

1

1

High-throughput

0.479

High

205096

WASF3
Actin-binding protein WASF3

1

3

High-throughput

0.479

High

205097

ACLY
ATP-citrate synthase

1

1

High-throughput

0.479

High

205099

RMXL1
RNA binding motif protein, X-linked-like-1

1

2

High-throughput

0.479

High

205104

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

1

High-throughput

0.479

High

205106

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

5

High-throughput

0.479

High

205108

MYO5A
Unconventional myosin-Va

1

1

High-throughput

0.479

High

205109

NRBP
Nuclear receptor-binding protein

1

4

High-throughput

0.479

High

205110

ARP3
Actin-related protein 3

1

3

High-throughput

0.479

High

205111

PLST
Plastin-3

1

2

High-throughput

0.479

High

205116

RTN4
Reticulon-4

1

1

High-throughput

0.479

High

205125

ILEUA
Leukocyte elastase inhibitor A

1

3

High-throughput

0.479

High

205126

TBCB
Tubulin-folding cofactor B

1

2

High-throughput

0.479

High

205127

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.479

High

205138

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.479

High

205139

ACTN2
Alpha-actinin-2

1

1

High-throughput

0.479

High

205140

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

205144

DREB
Drebrin

1

6

High-throughput

0.479

High

205147

PCLO
Protein piccolo

1

5

High-throughput

0.479

High

205154

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

205155

E41L3
Band 4.1-like protein 3

1

2

High-throughput

0.479

High

205156

CLIP2
CAP-Gly domain-containing linker protein 2

1

2

High-throughput

0.479

High

205160

STRAP
Serine-threonine kinase receptor-associated protein

1

2

High-throughput

0.479

High

205161

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.479

High

205162

HOME1
Homer protein homolog 1

1

1

High-throughput

0.479

High

204976

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.458

High

204978

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

High-throughput

0.458

High

204985

AP2A1
AP-2 complex subunit alpha-1

1

0

High-throughput

0.458

High

204989

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.458

High

204991

PABP1
Polyadenylate-binding protein 1

1

0

High-throughput

0.458

High

205007

PLPP
Chronophin

1

0

High-throughput

0.458

High

205012

PROF1
Profilin-1

1

0

High-throughput

0.458

High

205015

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

0

High-throughput

0.458

High

205027

IQEC3
IQ motif and SEC7 domain-containing protein 3

1

0

High-throughput

0.458

High

205031

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

1

0

High-throughput

0.458

High

205036

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.458

High

205042

FSCN1
Fascin

1

0

High-throughput

0.458

High

205044

GDIB
Rab GDP dissociation inhibitor beta

1

0

High-throughput

0.458

High

205048

TSN
Translin

1

0

High-throughput

0.458

High

205052

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.458

High

205061

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.458

High

205063

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.458

High

205078

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.458

High

205082

PGM2L
Glucose 1,6-bisphosphate synthase

1

0

High-throughput

0.458

High

205086

PDXK
Pyridoxal kinase

1

0

High-throughput

0.458

High

205088

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.458

High

205089

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

High-throughput

0.458

High

205095

EPMIP
EPM2A-interacting protein 1

1

0

High-throughput

0.458

High

205098

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.458

High

205100

DDX1
ATP-dependent RNA helicase DDX1

1

0

High-throughput

0.458

High

205101

ACSL6
Long-chain-fatty-acid--CoA ligase 6

1

0

High-throughput

0.458

High

205102

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.458

High

205107

TALDO
Transaldolase

1

0

High-throughput

0.458

High

205112

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

205113

MLF2
Myeloid leukemia factor 2

1

0

High-throughput

0.458

High

205119

NECP1
Adaptin ear-binding coat-associated protein 1

1

0

High-throughput

0.458

High

205120

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

High-throughput

0.458

High

205123

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

205124

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

205128

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.458

High

205129

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.458

High

205130

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

205131

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.458

High

205133

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.458

High

205135

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

205137

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.458

High

205141

LANC2
LanC-like protein 2

1

0

High-throughput

0.458

High

205143

SRCN1
SRC kinase signaling inhibitor 1

1

0

High-throughput

0.458

High

205145

CLIC4
Chloride intracellular channel protein 4

1

0

High-throughput

0.458

High

205149

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

0

High-throughput

0.458

High

205157

VATC1
V-type proton ATPase subunit C 1

1

0

High-throughput

0.458

High

205158

NFS1
Cysteine desulfurase

1

0

High-throughput

0.458

High

204982

CADH1
Cadherin-1

1

2

Small-scale

0.445

High

204981

CFAD
Complement factor D

1

20

High-throughput

0.437

High

204993

CALX
Calnexin

1

17

High-throughput

0.437

High

205003

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

1

High-throughput

0.437

High

205020

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.437

High

205034

OXR1
Oxidation resistance protein 1

1

1

High-throughput

0.437

High

205051

MTCL3
Microtubule cross-linking factor 3

1

4

High-throughput

0.437

High

205059

Q7TN25
Splicing factor 3A subunit 2

1

5

High-throughput

0.437

High

205060

Q7TQG5
Neogenin

1

5

High-throughput

0.437

High

205064

SEPT9
Septin-9

1

2

High-throughput

0.437

High

205066

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

205072

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

1

High-throughput

0.437

High

205079

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

1

High-throughput

0.437

High

205080

Q8C845
EF hand domain containing 2

1

1

High-throughput

0.437

High

205083

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

1

High-throughput

0.437

High

205087

Q8K1M3
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

2

High-throughput

0.437

High

205105

WDR7
WD repeat-containing protein 7

1

1

High-throughput

0.437

High

205115

Q99N15
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.437

High

205122

CSN7A
COP9 signalosome complex subunit 7a

1

2

High-throughput

0.437

High

205142

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.437

High

205148

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.437

High

205150

PSA4
Proteasome subunit alpha type-4

1

1

High-throughput

0.437

High

205151

SEPT6
Septin-6

1

2

High-throughput

0.437

High

92765

D3Z656
Synaptojanin-1

1

0

High-throughput

0.249

Low

204980

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.249

Low

204984

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.249

Low

204994

RP3A
Rabphilin-3A

1

0

High-throughput

0.249

Low

204995

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.249

Low

205000

ACADL
Long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

205028

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.249

Low

205035

ERMIN
Ermin

1

0

High-throughput

0.249

Low

205058

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.249

Low

205074

ZC21A
Zinc finger C2HC domain-containing protein 1A

1

0

High-throughput

0.249

Low

205103

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

205114

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

205117

GLOD4
Glyoxalase domain-containing protein 4

1

0

High-throughput

0.249

Low

205118

NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

1

0

High-throughput

0.249

Low

205121

QPCT
Glutaminyl-peptide cyclotransferase

1

0

High-throughput

0.249

Low

205132

BTBDH
BTB/POZ domain-containing protein 17

1

0

High-throughput

0.249

Low

205134

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.249

Low

205136

RPGF4
Rap guanine nucleotide exchange factor 4

1

0

High-throughput

0.249

Low

205146

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.249

Low

205152

VATG2
V-type proton ATPase subunit G 2

1

0

High-throughput

0.249

Low

205153

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.249

Low

205159

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025