Protein: SEPR
Prolyl endopeptidase FAP (EC 3.4.21.26) (170 kDa melanoma membrane-bound gelatinase) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)]

Gene: SEPR, FAP
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q12884

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002020 - protease binding
GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005178 - integrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341680

ADA
Adenosine deaminase

1

1

Small-scale

0.618

High

648741

DPP4
Dipeptidyl peptidase 4

1

10

Small-scale

0.618

High

351822

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

1

Small-scale

0.501

High

351857

SLIB
Somatoliberin

1

1

Small-scale

0.501

High

351873

NPY
Pro-neuropeptide Y [Cleaved into: Neuropeptide Y

1

3

Small-scale

0.501

High

454087

GIP
Gastric inhibitory polypeptide

1

1

Small-scale

0.501

High

485874

PYY
Peptide YY

1

3

Small-scale

0.501

High

562161

ANFB
Natriuretic peptides B

1

1

Small-scale

0.501

High

592783

TKN1
Protachykinin-1

1

1

Small-scale

0.501

High

976208

UPAR
Urokinase plasminogen activator surface receptor

1

0

Small-scale

0.480

High

299886

ERLN2
Erlin-2

1

2

Small-scale

0.479

High

646177

STOM
Stomatin

1

5

Small-scale

0.479

High

718803

PHB1
Prohibitin 1

1

5

Small-scale

0.479

High

958179

RBM3
RNA-binding protein 3

1

1

Small-scale

0.479

High

974785

CAV1
Caveolin-1

1

1

Small-scale

0.479

High

1018923

PHB2
Prohibitin-2

1

5

Small-scale

0.479

High

205338

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

346650

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

380182

THY1
Thy-1 membrane glycoprotein

1

0

Small-scale

0.458

High

1018925

RBM4
RNA-binding protein 4

1

0

Small-scale

0.458

High

1018926

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

351844

VIP
VIP peptides [Cleaved into: Intestinal peptide PHV-42

1

5

Small-scale

0.457

High

577460

PACA
Pituitary adenylate cyclase-activating polypeptide

1

3

Small-scale

0.457

High

1018924

TM109
Voltage-gated monoatomic cation channel TMEM109

1

0

Small-scale

0.249

Low

1018927

MSRB1
Methionine-R-sulfoxide reductase B1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024