Protein: MBTP2
Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease)

Gene: MBTP2, MBTPS2
Organism: Homo sapiens
Interactions: 15
UniProt ID: O43462

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004222 - metalloendopeptidase activity
GO:0005737 - cytoplasm
GO:0007095 - mitotic G2 DNA damage checkpoint signaling
GO:0008203 - cholesterol metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

216347

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

0

High-throughput

0.513

High

216333

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

216338

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

0

High-throughput

0.458

High

216344

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.458

High

216345

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

216334

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

216335

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.426

High

216341

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.426

High

216342

SARAF
Store-operated calcium entry-associated regulatory factor

2

0

High-throughput

0.313

High

216346

FA8A1
Protein FAM8A1

2

0

High-throughput

0.313

High

216336

CO032
Uncharacterized protein C15orf32

1

0

High-throughput

0.279

Low

216337

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

216339

I17RC
Interleukin-17 receptor C

1

0

High-throughput

0.279

Low

216340

OR6T1
Olfactory receptor 6T1

1

0

High-throughput

0.279

Low

216343

BSCL2
Seipin

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025