Protein: SARAF
Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (HBV X-transactivated gene 3 protein) (HBV XAg-transactivated protein 3) (Protein FOAP-7) (Transmembrane protein 66)

Gene: SARAF
Organism: Homo sapiens
Interactions: 218
UniProt ID: Q96BY9

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006816 - calcium ion transport
GO:0140268 - endoplasmic reticulum-plasma membrane contact site
GO:2001256 - regulation of store-operated calcium entry

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1385184

FAF2
FAS-associated factor 2

3

0

High-throughput

0.638

High

1385206

CC50A
Cell cycle control protein 50A

3

0

High-throughput

0.638

High

1385198

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

3

2

Small-scale

0.609

High

595093

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

1

High-throughput

0.601

High

1385187

ITCH
E3 ubiquitin-protein ligase Itchy homolog

3

2

High-throughput

0.599

High

276504

PDCD6
Programmed cell death protein 6

1

3

Small-scale

0.578

High

142148

NPT3
Sodium-dependent phosphate transport protein 3

2

1

High-throughput

0.574

High

320484

TM63A
Mechanosensitive cation channel TMEM63A

2

2

High-throughput

0.574

High

648833

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

1

High-throughput

0.574

High

1355975

ABHD5
1-acylglycerol-3-phosphate O-acyltransferase ABHD5

2

1

High-throughput

0.574

High

1111649

STIM1
Stromal interaction molecule 1

2

0

Small-scale

0.569

High

369378

A1AT
Alpha-1-antitrypsin

1

9

High-throughput

0.536

High

387742

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

3

High-throughput

0.536

High

387871

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.536

High

390134

ALBU
Albumin

1

1

High-throughput

0.536

High

423824

APOD
Apolipoprotein D

1

1

High-throughput

0.536

High

607968

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

1

High-throughput

0.536

High

724616

S10A7
Protein S100-A7

1

4

High-throughput

0.536

High

1085362

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

1

High-throughput

0.536

High

1185822

PTHD3
Patched domain-containing protein 3

1

1

High-throughput

0.536

High

1369672

KLK6
Kallikrein-6

1

2

High-throughput

0.536

High

1385210

TM63C
Osmosensitive cation channel TMEM63C

1

2

High-throughput

0.536

High

297244

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.513

High

338241

G6PE
GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase

1

0

High-throughput

0.513

High

483948

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.513

High

578698

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

635663

ASPG
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase

1

0

High-throughput

0.513

High

690339

STOM
Stomatin

1

0

High-throughput

0.513

High

1058579

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.513

High

1154067

MSMO1
Methylsterol monooxygenase 1

1

0

High-throughput

0.513

High

1231239

NB5R2
NADH-cytochrome b5 reductase 2

1

0

High-throughput

0.513

High

1272460

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.513

High

1276266

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

1325560

RDHE2
Epidermal retinol dehydrogenase 2

1

0

High-throughput

0.513

High

1385199

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

1385221

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

210770

KLK10
Kallikrein-10

1

2

High-throughput

0.489

High

248498

O10H2
Olfactory receptor 10H2

1

2

High-throughput

0.489

High

248753

PEPL
Periplakin

1

1

High-throughput

0.489

High

261645

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

276615

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

1

High-throughput

0.489

High

289275

SPB7
Serpin B7

1

9

High-throughput

0.489

High

295398

CBR3
Carbonyl reductase [NADPH] 3

1

1

High-throughput

0.489

High

361545

CERU
Ceruloplasmin

1

1

High-throughput

0.489

High

366197

HPT
Haptoglobin

1

1

High-throughput

0.489

High

369489

AACT
Alpha-1-antichymotrypsin

1

9

High-throughput

0.489

High

369905

CO3
Complement C3

1

3

High-throughput

0.489

High

380331

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

4

High-throughput

0.489

High

380649

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

4

High-throughput

0.489

High

387999

FIBG
Fibrinogen gamma chain

1

3

High-throughput

0.489

High

390298

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.489

High

390930

TRFE
Serotransferrin

1

1

High-throughput

0.489

High

391063

TRFL
Lactotransferrin

1

1

High-throughput

0.489

High

391153

HEMO
Hemopexin

1

1

High-throughput

0.489

High

409599

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

5

High-throughput

0.489

High

424245

S10A8
Protein S100-A8

1

2

High-throughput

0.489

High

424537

PAI2
Plasminogen activator inhibitor 2

1

8

High-throughput

0.489

High

445043

S10A9
Protein S100-A9

1

4

High-throughput

0.489

High

472340

CFAH
Complement factor H

1

1

High-throughput

0.489

High

485811

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

1

High-throughput

0.489

High

501846

CO4A
Complement C4-A

1

3

High-throughput

0.489

High

539731

ACHB
Acetylcholine receptor subunit beta

1

1

High-throughput

0.489

High

590991

LOX15
Polyunsaturated fatty acid lipoxygenase ALOX15

1

1

High-throughput

0.489

High

592874

CBR1
Carbonyl reductase [NADPH] 1

1

1

High-throughput

0.489

High

615226

IL1RA
Interleukin-1 receptor antagonist protein

1

2

High-throughput

0.489

High

631404

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.489

High

635623

FILA
Filaggrin

1

2

High-throughput

0.489

High

652384

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.489

High

713430

SPB3
Serpin B3

1

7

High-throughput

0.489

High

814898

MMP12
Macrophage metalloelastase

1

1

High-throughput

0.489

High

874840

SPB4
Serpin B4

1

7

High-throughput

0.489

High

895461

SPB8
Serpin B8

1

7

High-throughput

0.489

High

945836

EPIPL
Epiplakin

1

2

High-throughput

0.489

High

956599

RAB5B
Ras-related protein Rab-5B

1

1

High-throughput

0.489

High

1009160

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

5

High-throughput

0.489

High

1009695

NGAL
Neutrophil gelatinase-associated lipocalin

1

1

High-throughput

0.489

High

1062282

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

1126247

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

1

High-throughput

0.489

High

1187259

PA24E
Cytosolic phospholipase A2 epsilon

1

1

High-throughput

0.489

High

1212279

TM63B
Mechanosensitive cation channel TMEM63B

1

2

High-throughput

0.489

High

1236031

HPHL1
Ferroxidase HEPHL1

1

1

High-throughput

0.489

High

1286343

S1A7A
Protein S100-A7A

1

4

High-throughput

0.489

High

1292434

SPA9
Serpin A9

1

9

High-throughput

0.489

High

1294067

PA24D
Cytosolic phospholipase A2 delta

1

4

High-throughput

0.489

High

1309608

SPA12
Serpin A12

1

9

High-throughput

0.489

High

1316216

S22AF
Solute carrier family 22 member 15

1

1

High-throughput

0.489

High

1336912

VGLU3
Vesicular glutamate transporter 3

1

1

High-throughput

0.489

High

1338058

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

1

High-throughput

0.489

High

1339946

OR4N2
Olfactory receptor 4N2

1

1

High-throughput

0.489

High

1339992

O10S1
Olfactory receptor 10S1

1

1

High-throughput

0.489

High

1368993

EVPL
Envoplakin

1

2

High-throughput

0.489

High

1385189

CPNS2
Calpain small subunit 2

1

3

High-throughput

0.489

High

1385208

IL36G
Interleukin-36 gamma

1

2

High-throughput

0.489

High

1385209

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.489

High

1385212

I36RA
Interleukin-36 receptor antagonist protein

1

2

High-throughput

0.489

High

1385216

SPB13
Serpin B13

1

7

High-throughput

0.489

High

1385222

O10H1
Olfactory receptor 10H1

1

2

High-throughput

0.489

High

1287402

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

Small-scale

0.479

High

1385218

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

Small-scale

0.479

High

133780

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

564180

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

1249094

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1385197

DERL2
Derlin-2

1

0

Small-scale

0.458

High

1385213

SE1L1
Protein sel-1 homolog 1

1

0

Small-scale

0.458

High

1335668

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.445

High

161150

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.438

High

75706

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

3

High-throughput

0.437

High

418341

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.426

High

1126336

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.426

High

1346752

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.426

High

1385185

MRAP2
Melanocortin-2 receptor accessory protein 2

1

0

High-throughput

0.426

High

1385186

BSCL2
Seipin

1

0

High-throughput

0.426

High

1385220

S27A5
Long-chain fatty acid transport protein 5

1

0

High-throughput

0.426

High

142020

FCN1
Ficolin-1

1

3

Small-scale

0.417

High

69529

A2ML1
Alpha-2-macroglobulin-like protein 1

1

3

High-throughput

0.407

High

379128

IGKC
Immunoglobulin kappa constant

1

4

High-throughput

0.407

High

379291

IGHG1
Immunoglobulin heavy constant gamma 1

1

3

High-throughput

0.407

High

379382

IGHG2
Immunoglobulin heavy constant gamma 2

1

4

High-throughput

0.407

High

379470

IGHG4
Immunoglobulin heavy constant gamma 4

1

3

High-throughput

0.407

High

380573

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

5

High-throughput

0.407

High

861718

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

High-throughput

0.407

High

1326969

SVOP
Synaptic vesicle 2-related protein

1

1

High-throughput

0.407

High

1384618

S67A1
Solute carrier family 67 member A1

1

2

High-throughput

0.407

High

1385193

S1PR3
Sphingosine 1-phosphate receptor 3

1

1

High-throughput

0.407

High

1323873

SYNE4
Nesprin-4

3

0

High-throughput

0.347

High

191971

TEX28
Testis-specific protein TEX28

3

0

High-throughput

0.345

High

749798

CADH5
Cadherin-5

2

0

High-throughput

0.328

High

1029438

IL9R
Interleukin-9 receptor

2

0

High-throughput

0.318

High

216342

MBTP2
Membrane-bound transcription factor site-2 protease

2

0

High-throughput

0.313

High

1106807

VPP3
V-type proton ATPase 116 kDa subunit a 3

2

0

High-throughput

0.313

High

639632

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

1116393

5HT4R
5-hydroxytryptamine receptor 4

1

0

High-throughput

0.282

High

161886

IMPA2
Inositol monophosphatase 2

1

0

High-throughput

0.279

Low

230201

S28A2
Sodium/nucleoside cotransporter 2

1

0

High-throughput

0.279

Low

270165

LRP3
Low-density lipoprotein receptor-related protein 3

1

0

High-throughput

0.279

Low

277773

H2AY
Core histone macro-H2A.1

1

0

High-throughput

0.279

Low

333869

PAPS2
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

1

0

High-throughput

0.279

Low

348882

CLIC3
Chloride intracellular channel protein 3

1

0

High-throughput

0.279

Low

358894

AL1A1
Aldehyde dehydrogenase 1A1

1

0

High-throughput

0.279

Low

366365

PLMN
Plasminogen

1

0

High-throughput

0.279

Low

366585

CFAB
Complement factor B

1

0

High-throughput

0.279

Low

387306

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.279

Low

388586

SAMP
Serum amyloid P-component

1

0

High-throughput

0.279

Low

389671

A1AG1
Alpha-1-acid glycoprotein 1

1

0

High-throughput

0.279

Low

405618

HRG
Histidine-rich glycoprotein

1

0

High-throughput

0.279

Low

423691

ARGI1
Arginase-1

1

0

High-throughput

0.279

Low

457900

INVO
Involucrin

1

0

High-throughput

0.279

Low

471467

PLEK
Pleckstrin

1

0

High-throughput

0.279

Low

474883

VIME
Vimentin

1

0

High-throughput

0.279

Low

568164

PLSL
Plastin-2

1

0

High-throughput

0.279

Low

568971

ANXA8
Annexin A8

1

0

High-throughput

0.279

Low

582605

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.279

Low

609320

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

626015

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

0

High-throughput

0.279

Low

627146

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

636179

ENDOU
Uridylate-specific endoribonuclease

1

0

High-throughput

0.279

Low

658974

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

0

High-throughput

0.279

Low

671838

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.279

Low

692772

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

729600

CASPE
Caspase-14

1

0

High-throughput

0.279

Low

748656

DSG3
Desmoglein-3

1

0

High-throughput

0.279

Low

771804

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

827884

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.279

Low

833158

MNDA
Myeloid cell nuclear differentiation antigen

1

0

High-throughput

0.279

Low

839608

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

842225

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.279

Low

868754

LEG7
Galectin-7

1

0

High-throughput

0.279

Low

877367

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.279

Low

912636

GDIR2
Rho GDP-dissociation inhibitor 2

1

0

High-throughput

0.279

Low

931278

AT12A
Potassium-transporting ATPase alpha chain 2

1

0

High-throughput

0.279

Low

1031121

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

0

High-throughput

0.279

Low

1061272

RHG01
Rho GTPase-activating protein 1

1

0

High-throughput

0.279

Low

1097256

S13A2
Solute carrier family 13 member 2

1

0

High-throughput

0.279

Low

1120946

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

1143002

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.279

Low

1159403

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1211817

DCST1
E3 ubiquitin-protein ligase DCST1

1

0

High-throughput

0.279

Low

1213803

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

1219528

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.279

Low

1242355

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

1253041

ACP7
Acid phosphatase type 7

1

0

High-throughput

0.279

Low

1256970

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

1315976

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1316341

AGRG5
Adhesion G-protein coupled receptor G5

1

0

High-throughput

0.279

Low

1333588

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1340022

O13J1
Olfactory receptor 13J1

1

0

High-throughput

0.279

Low

1358543

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1385188

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

1385190

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

1385192

NIBA2
Protein Niban 2

1

0

High-throughput

0.279

Low

1385196

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

1385200

RNAS7
Ribonuclease 7

1

0

High-throughput

0.279

Low

1385201

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.279

Low

1385203

EHD1
EH domain-containing protein 1

1

0

High-throughput

0.279

Low

1385204

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.279

Low

1385207

ARL8B
ADP-ribosylation factor-like protein 8B

1

0

High-throughput

0.279

Low

1385211

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

1385214

PCYOX
Prenylcysteine oxidase 1

1

0

High-throughput

0.279

Low

1385215

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.279

Low

1385217

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.279

Low

1385219

NDRG2
Protein NDRG2

1

0

High-throughput

0.279

Low

1385223

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

0

High-throughput

0.279

Low

218605

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

626324

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.249

Low

675100

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.249

Low

1004946

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1102497

IFIT5
Interferon-induced protein with tetratricopeptide repeats 5

1

0

High-throughput

0.238

Low

1385202

RIBC2
RIB43A-like with coiled-coils protein 2

1

0

High-throughput

0.238

Low

1385205

SNX15
Sorting nexin-15

1

0

High-throughput

0.238

Low

876435

EAA4
Excitatory amino acid transporter 4

1

0

High-throughput

0.232

Low

1199016

KLH12
Kelch-like protein 12

1

0

High-throughput

0.232

Low

1216235

H37
Histone H3-7

1

0

High-throughput

0.232

Low

1249746

S49A3
Solute carrier family 49 member A3

1

0

High-throughput

0.232

Low

1288435

SO6A1
Solute carrier organic anion transporter family member 6A1

1

0

High-throughput

0.232

Low

1359476

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.232

Low

1385191

S26A8
Testis anion transporter 1

1

0

High-throughput

0.232

Low

1385194

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.232

Low

1385195

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025