Protein: IL2RG
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)

Gene: IL2RG
Organism: Homo sapiens
Interactions: 33
UniProt ID: P31785

Gene Ontology (top 5):
GO:0002335 - mature B cell differentiation
GO:0002361 - CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0004896 - cytokine receptor activity
GO:0005654 - nucleoplasm
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

540448

IL2RB
Interleukin-2 receptor subunit beta

8

19

Small-scale

0.748

High

682256

JAK3
Tyrosine-protein kinase JAK3

5

20

Small-scale

0.704

High

682259

IL2
Interleukin-2

4

2

Small-scale

0.687

High

682254

IL15
Interleukin-15

3

1

Small-scale

0.664

High

526541

IL7
Interleukin-7

3

1

Small-scale

0.650

High

562523

IL7RA
Interleukin-7 receptor subunit alpha

3

2

Small-scale

0.640

High

682267

REEP6
Receptor expression-enhancing protein 6

3

0

High-throughput

0.638

High

682273

FLVC1
Heme transporter FLVCR1

3

0

High-throughput

0.638

High

682270

CD320
CD320 antigen

2

8

High-throughput

0.628

High

616945

PTPRD
Receptor-type tyrosine-protein phosphatase delta

2

18

High-throughput

0.611

High

622725

IL4RA
Interleukin-4 receptor subunit alpha

2

16

Small-scale

0.611

High

682258

KR108
Keratin-associated protein 10-8

2

2

High-throughput

0.606

High

682265

KRA57
Keratin-associated protein 5-7

2

3

High-throughput

0.606

High

238367

JAK2
Tyrosine-protein kinase JAK2

2

20

Small-scale

0.601

High

682266

NT2NA
Notch homolog 2 N-terminal-like protein A

2

8

High-throughput

0.573

High

682262

STK4
Serine/threonine-protein kinase 4

1

13

High-throughput

0.541

High

396849

IL4
Interleukin-4

1

3

Small-scale

0.536

High

682261

I13R1
Interleukin-13 receptor subunit alpha-1

1

19

Small-scale

0.515

High

682269

IL21
Interleukin-21

1

0

Small-scale

0.512

High

682253

IL2RG
Cytokine receptor common subunit gamma

1

17

Small-scale

0.501

High

682264

SHB
SH2 domain-containing adapter protein B

1

20

Small-scale

0.501

High

385845

CPNS1
Calpain small subunit 1

1

3

Small-scale

0.481

High

682257

KR103
Keratin-associated protein 10-3

1

2

High-throughput

0.481

High

353047

IL2RA
Interleukin-2 receptor subunit alpha

1

2

Small-scale

0.479

High

616744

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.479

High

666008

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.479

High

682255

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

5

Small-scale

0.479

High

682260

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

682263

GRB10
Growth factor receptor-bound protein 10

1

20

Small-scale

0.479

High

682268

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

5

Small-scale

0.479

High

682272

ERRFI
ERBB receptor feedback inhibitor 1

1

0

Small-scale

0.460

High

682271

NFIP2
NEDD4 family-interacting protein 2

1

0

High-throughput

0.458

High


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Last updated: 15 Jul 2024