Protein: ITB2
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)

Gene: ITB2, Itgb2
Organism: Mus musculus
Interactions: 66
UniProt ID: P11835

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001851 - complement component C3b binding
GO:0006898 - receptor-mediated endocytosis
GO:0006911 - phagocytosis, engulfment
GO:0007155 - cell adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

98114

E9Q604
Integrin alpha M

1

20

High-throughput

0.647

High

549371

ITB2
Integrin beta-2

1

12

High-throughput

0.647

High

549376

TLN1
Talin-1

1

20

High-throughput

0.647

High

549375

ITAL
Integrin alpha-L

1

20

Small-scale

0.618

High

549394

FLNB
Filamin-B

1

20

High-throughput

0.579

High

549398

FLNA
Filamin-A

1

20

High-throughput

0.579

High

549408

FLNC
Filamin-C

1

20

High-throughput

0.579

High

107475

F8WIE5
E3 ubiquitin-protein ligase

1

15

High-throughput

0.501

High

312907

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

3

High-throughput

0.501

High

369946

CO3
Complement C3

1

2

High-throughput

0.501

High

549380

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

10

High-throughput

0.501

High

549386

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.501

High

549388

MYOF
Myoferlin

1

5

High-throughput

0.501

High

549395

LIMD2
LIM domain-containing protein 2

1

4

High-throughput

0.501

High

549404

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

2

High-throughput

0.501

High

549423

DREB
Drebrin

1

7

High-throughput

0.501

High

549420

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

6

Small-scale

0.479

High

549385

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.458

High

59208

SPD2B
SH3 and PX domain-containing protein 2B

1

3

High-throughput

0.457

High

59676

UBR4
E3 ubiquitin-protein ligase UBR4

1

2

High-throughput

0.457

High

59698

A2ANY6
Midasin

1

10

High-throughput

0.457

High

73143

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

11

High-throughput

0.457

High

86334

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.457

High

98281

HELZ2
3'-5' exoribonuclease HELZ2

1

7

High-throughput

0.457

High

104748

TPR
Nucleoprotein TPR

1

8

High-throughput

0.457

High

108411

G3X9H5
Huntingtin

1

2

High-throughput

0.457

High

549372

MAP1B
Microtubule-associated protein 1B

1

4

High-throughput

0.457

High

549373

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

1

High-throughput

0.457

High

549377

RADI
Radixin

1

6

High-throughput

0.457

High

549378

UBA1Y
Ubiquitin-like modifier-activating enzyme 1 Y

1

2

High-throughput

0.457

High

549381

WNK1
Serine/threonine-protein kinase WNK1

1

8

High-throughput

0.457

High

549387

Q68FM7
Rho guanine nucleotide exchange factor 11

1

6

High-throughput

0.457

High

549389

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.457

High

549390

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

4

High-throughput

0.457

High

549391

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

12

High-throughput

0.457

High

549393

UBP2L
Ubiquitin-associated protein 2-like

1

1

High-throughput

0.457

High

549396

Q8BIX2
GCN1 activator of EIF2AK4

1

10

High-throughput

0.457

High

549397

SRRM2
Serine/arginine repetitive matrix protein 2

1

3

High-throughput

0.457

High

549400

TAOK3
Serine/threonine-protein kinase TAO3

1

3

High-throughput

0.457

High

549401

SMC4
Structural maintenance of chromosomes protein 4

1

8

High-throughput

0.457

High

549402

SMC2
Structural maintenance of chromosomes protein 2

1

9

High-throughput

0.457

High

549403

TCRG1
Transcription elongation regulator 1

1

3

High-throughput

0.457

High

549405

IPO11
Importin-11

1

9

High-throughput

0.457

High

549406

SF3A1
Splicing factor 3A subunit 1

1

4

High-throughput

0.457

High

549407

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.457

High

549409

PECR
Peroxisomal trans-2-enoyl-CoA reductase

1

2

High-throughput

0.457

High

549417

XPO7
Exportin-7

1

6

High-throughput

0.457

High

549419

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

5

High-throughput

0.457

High

549421

SON
Protein SON

1

8

High-throughput

0.457

High

549422

PLEC
Plectin

1

13

High-throughput

0.457

High

549384

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.437

High

549392

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.437

High

549412

1433B
14-3-3 protein beta/alpha

1

4

Small-scale

0.437

High

549383

S39A7
Zinc transporter SLC39A7

1

1

High-throughput

0.417

High

549416

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

2

High-throughput

0.417

High

549374

CBL
E3 ubiquitin-protein ligase CBL

1

4

High-throughput

0.407

High

549379

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.261

Low

549382

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.261

Low

549399

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.261

Low

549410

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.261

Low

549411

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.261

Low

549413

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.261

Low

549414

NOP56
Nucleolar protein 56

1

0

High-throughput

0.261

Low

549415

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.261

Low

549418

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025