Protein: PP1RB
E3 ubiquitin-protein ligase PPP1R11 (EC 2.3.2.27) (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase 1 regulatory subunit 11) (Protein phosphatase inhibitor 3)

Gene: PP1RB, PPP1R11
Organism: Homo sapiens
Interactions: 23
UniProt ID: O60927

Gene Ontology (top 5):
GO:0001818 - negative regulation of cytokine production
GO:0004864 - protein phosphatase inhibitor activity
GO:0004865 - protein serine/threonine phosphatase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

246074

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

10

20

Small-scale

0.758

High

246078

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

7

20

High-throughput

0.751

High

246077

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

7

20

High-throughput

0.751

High

246081

UBX2B
UBX domain-containing protein 2B

5

2

Small-scale

0.719

High

246080

UBX2A
UBX domain-containing protein 2A

4

2

High-throughput

0.694

High

246075

TERA
Transitional endoplasmic reticulum ATPase

3

1

Small-scale

0.664

High

246082

PP1R7
Protein phosphatase 1 regulatory subunit 7

2

1

Small-scale

0.611

High

246085

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.580

High

246086

YAF2
YY1-associated factor 2

2

0

High-throughput

0.580

High

246083

PPR3A
Protein phosphatase 1 regulatory subunit 3A

2

0

Small-scale

0.569

High

246070

LATS1
Serine/threonine-protein kinase LATS1

1

1

Small-scale

0.501

High

246088

H2B1M
Histone H2B type 1-M

1

0

High-throughput

0.493

High

246069

CSTN1
Calsyntenin-1

1

0

High-throughput

0.493

High

246076

CASP6
Caspase-6

1

0

High-throughput

0.493

High

246079

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

246087

OPTN
Optineurin

1

0

High-throughput

0.493

High

246090

UBQL1
Ubiquilin-1

1

0

High-throughput

0.493

High

246073

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.480

High

246091

NSF1C
NSFL1 cofactor p47

1

2

High-throughput

0.479

High

246089

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

246084

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.437

High

246071

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

246072

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024