Protein: CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)

Gene: CYLD
Organism: Mus musculus
Interactions: 26
UniProt ID: Q80TQ2

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005813 - centrosome
GO:0005819 - spindle
GO:0005829 - cytosol
GO:0005881 - cytoplasmic microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476863

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

4

Small-scale

0.768

High

1145344

SQSTM
Sequestosome-1

4

4

Small-scale

0.687

High

936243

TRAF6
TNF receptor-associated factor 6

3

11

Small-scale

0.657

High

1193467

BCL3
B-cell lymphoma 3 protein homolog

2

3

Small-scale

0.608

High

1193463

ITCH
E3 ubiquitin-protein ligase Itchy

2

2

Small-scale

0.601

High

291808

NEMO
NF-kappa-B essential modulator

2

3

Small-scale

0.584

High

1193464

RNF31
E3 ubiquitin-protein ligase RNF31

1

2

Small-scale

0.561

High

1115983

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

2

High-throughput

0.536

High

411928

LCK
Proto-oncogene tyrosine-protein kinase LCK

1

2

Small-scale

0.515

High

292702

CASP8
Caspase-8

1

2

Small-scale

0.501

High

933729

TBA1A
Tubulin alpha-1A chain

1

6

Small-scale

0.500

High

345620

FOS
Protein c-Fos

1

1

Small-scale

0.479

High

886055

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

2

Small-scale

0.479

High

1110871

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

1141415

TRAF3
TNF receptor-associated factor 3

1

8

Small-scale

0.479

High

1141526

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

3

Small-scale

0.479

High

1143255

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

Small-scale

0.479

High

1143370

DLG4
Disks large homolog 4

1

2

High-throughput

0.479

High

1193461

SMAD3
Mothers against decapentaplegic homolog 3

1

1

Small-scale

0.479

High

1193462

TRI47
E3 ubiquitin-protein ligase TRIM47

1

3

Small-scale

0.479

High

1193468

HDAC6
Histone deacetylase 6

1

1

Small-scale

0.479

High

404149

JUN
Transcription factor Jun

1

0

Small-scale

0.458

High

786554

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.458

High

1112478

NTRK1
High affinity nerve growth factor receptor

1

3

Small-scale

0.437

High

1193466

SRCN1
SRC kinase signaling inhibitor 1

1

0

High-throughput

0.426

High

1193465

DLGP1
Disks large-associated protein 1

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024