Protein: JAK3
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3)

Gene: JAK3
Organism: Mus musculus
Interactions: 11
UniProt ID: Q62137

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0002731 - negative regulation of dendritic cell cytokine production
GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005131 - growth hormone receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1143581

JAK3
Tyrosine-protein kinase JAK3

3

19

Small-scale

0.845

High

786537

STAT3
Signal transducer and activator of transcription 3

2

20

Small-scale

0.776

High

936444

STAM1
Signal transducing adapter molecule 1

1

20

Small-scale

0.647

High

786655

STA5A
Signal transducer and activator of transcription 5A

1

20

Small-scale

0.618

High

292664

SP1
Transcription factor Sp1

2

8

Small-scale

0.584

High

1143322

DLG4
Disks large homolog 4

1

20

High-throughput

0.575

High

1143584

SH2B1
SH2B adapter protein 1

1

20

Small-scale

0.575

High

1143582

FACD2
Fanconi anemia group D2 protein homolog

1

9

High-throughput

0.479

High

1143583

ANM5
Protein arginine N-methyltransferase 5

1

9

Small-scale

0.479

High

1143585

GANP
Germinal-center associated nuclear protein

1

11

Small-scale

0.479

High


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Last updated: 15 Jul 2024