Protein: SYL
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)

Gene: SYL, leuS
Organism: Thermococcus kodakarensis KOD1
Interactions: 115
UniProt ID: Q8NKR7

Gene Ontology (top 5):
GO:0002161 - aminoacyl-tRNA editing activity
GO:0004823 - leucine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006429 - leucyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1126767

SYM
Methionine--tRNA ligase

1

18

High-throughput

0.575

High

1126753

SYC
Cysteine--tRNA ligase

1

10

High-throughput

0.445

High

1126755

Q5JD92
Predicted GTPase, containing TGS domain

1

5

High-throughput

0.445

High

1126770

Q5JE32
DNA-directed RNA polymerase subunit beta

1

1

High-throughput

0.445

High

1126776

Q5JEC3
Predicted DNA methylase

1

1

High-throughput

0.445

High

1126782

Q5JEZ6
non-specific serine/threonine protein kinase

1

1

High-throughput

0.445

High

1126785

SYP
Proline--tRNA ligase

1

11

High-throughput

0.445

High

1126786

SYY
Tyrosine--tRNA ligase

1

4

High-throughput

0.445

High

1126789

Q5JFI2
Probable acetylpolyamine aminohydrolase, histon deacetylase family

1

5

High-throughput

0.445

High

1126799

EF1A
Elongation factor 1-alpha

1

6

High-throughput

0.445

High

1126803

PYRG
CTP synthase

1

1

High-throughput

0.445

High

1126811

IF2P
Probable translation initiation factor IF-2 [Cleaved into: Pko infB intein

1

11

High-throughput

0.445

High

1126821

PYRB
Aspartate carbamoyltransferase catalytic subunit

1

5

High-throughput

0.445

High

1126831

Q5JI30
Thiamine-monophosphate kinase

1

1

High-throughput

0.445

High

1126836

Q5JID5
N2, N2-dimethylguanosine tRNA methyltransferase

1

2

High-throughput

0.445

High

1126837

SYG
Glycine--tRNA ligase

1

3

High-throughput

0.445

High

1126850

Q5JJ02
Sugar-phosphate nucleotydyltransferase

1

2

High-throughput

0.445

High

1126855

Q5JJB9
NADH:polysulfide oxidoreductase

1

7

High-throughput

0.445

High

1126862

RPO3
DNA-directed RNA polymerase subunit Rpo3

1

5

High-throughput

0.445

High

292766

GLPK
Glycerol kinase

1

0

High-throughput

0.426

High

1119788

THSB
Thermosome subunit beta

1

0

High-throughput

0.426

High

1126763

Q5JDR3
ATPase, RecA superfamily

1

0

High-throughput

0.426

High

1126780

RADA
DNA repair and recombination protein RadA [Cleaved into: Pko RadA intein]

1

0

High-throughput

0.426

High

1126787

Q5JF65
DEAD/DEAH box RNA helicase

1

0

High-throughput

0.426

High

1126793

GUAAB
GMP synthase [glutamine-hydrolyzing] subunit B

1

0

High-throughput

0.426

High

1126796

Q5JFX8
L-aspartate oxidase

1

0

High-throughput

0.426

High

1126801

PYRH
Uridylate kinase

1

0

High-throughput

0.426

High

1126805

Q5JGH8
lipoate--protein ligase

1

0

High-throughput

0.426

High

1126819

TOP6B
Type 2 DNA topoisomerase 6 subunit B

1

0

High-throughput

0.426

High

1126820

TOP6A
Type 2 DNA topoisomerase 6 subunit A

1

0

High-throughput

0.426

High

1126824

Q5JHS0
Deoxycytidylate deaminase

1

0

High-throughput

0.426

High

1126825

PAN
Proteasome-activating nucleotidase

1

0

High-throughput

0.426

High

1126849

Q5JIY0
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

1

0

High-throughput

0.426

High

1126853

Q5JJB0
5-methylcytosine restriction system, GTPase subunit

1

0

High-throughput

0.426

High

1126856

Q5JJC7
Isopentenyl phosphate kinase

1

0

High-throughput

0.426

High

1126859

KCY
Cytidylate kinase

1

0

High-throughput

0.426

High

1126866

KADA
Adenylate kinase

1

0

High-throughput

0.426

High

1176157

IDI2
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.426

High

1246701

FTSZ2
Cell division protein FtsZ 2

1

0

High-throughput

0.426

High

1126758

RS19
Small ribosomal subunit protein uS19

1

2

High-throughput

0.407

High

1126759

RS17
Small ribosomal subunit protein uS17

1

1

High-throughput

0.407

High

1126761

Q5JDI4
Probable serine--glyoxylate aminotransferase, class V

1

1

High-throughput

0.407

High

1126762

RS6E
Small ribosomal subunit protein eS6

1

1

High-throughput

0.407

High

1126768

RS12
Small ribosomal subunit protein uS12

1

3

High-throughput

0.407

High

1126771

RS27
Small ribosomal subunit protein eS27

1

3

High-throughput

0.407

High

1126779

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

1

High-throughput

0.407

High

1126781

ENO
Enolase

1

2

High-throughput

0.407

High

1126792

Q5JFK1
Acetyl-CoA acetyltransferase

1

1

High-throughput

0.407

High

1126794

Q5JFM7
Predicted glutamine amidotransferase, class I

1

2

High-throughput

0.407

High

1126798

EF2
Elongation factor 2

1

8

High-throughput

0.407

High

1126800

RS10
Small ribosomal subunit protein uS10

1

3

High-throughput

0.407

High

1126806

RS15
Small ribosomal subunit protein uS15

1

1

High-throughput

0.407

High

1126808

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.407

High

1126809

Q5JGN5
Small ribosomal subunit protein eS19

1

2

High-throughput

0.407

High

1126810

NSR
NAD(P)H sulfur oxidoreductase

1

4

High-throughput

0.407

High

1126813

Q5JGT0
Ferredoxin:NADP oxidoreductase, alpha subunit

1

5

High-throughput

0.407

High

1126822

MOAA
Probable GTP 3',8-cyclase

1

1

High-throughput

0.407

High

1126827

Q5JHY2

1

4

High-throughput

0.407

High

1126828

Q5JHZ0
Type A flavoprotein

1

1

High-throughput

0.407

High

1126829

Q5JI19

1

3

High-throughput

0.407

High

1126834

TRM1
tRNA

1

1

High-throughput

0.407

High

1126843

Q5JIJ0
cysteine desulfurase

1

2

High-throughput

0.407

High

1126846

Q5JIR0
Hydrolase, metallo-beta-lactamase superfamily

1

1

High-throughput

0.407

High

1126854

PNPH
Probable 6-oxopurine nucleoside phosphorylase

1

1

High-throughput

0.407

High

1126857

RS2
Small ribosomal subunit protein uS2

1

5

High-throughput

0.407

High

1126858

RS9
Small ribosomal subunit protein uS9

1

2

High-throughput

0.407

High

1126861

RS11
Small ribosomal subunit protein uS11

1

3

High-throughput

0.407

High

1126864

RS8
Small ribosomal subunit protein uS8

1

3

High-throughput

0.407

High

1126865

RS5
Small ribosomal subunit protein uS5

1

1

High-throughput

0.407

High

292767

RBL
Ribulose bisphosphate carboxylase

1

0

High-throughput

0.232

Low

1126752

MOAC
Probable cyclic pyranopterin monophosphate synthase

1

0

High-throughput

0.232

Low

1126754

Q5JD73
Bifunctional carboxypeptidase/aminoacylase

1

0

High-throughput

0.232

Low

1126756

Q5JD97
Aspartate racemase

1

0

High-throughput

0.232

Low

1126757

Q5JDE3
Iron-molybdenum cofactor-binding protein

1

0

High-throughput

0.232

Low

1126760

Q5JDI3
Predicetd ATPase

1

0

High-throughput

0.232

Low

1126764

Q5JDW4
D-aminopeptidase

1

0

High-throughput

0.232

Low

1126765

Q5JDX0
Metallophosphoesterase, calcineurin superfamily

1

0

High-throughput

0.232

Low

1126766

Q5JDZ0
Rubrerythrin-related protein

1

0

High-throughput

0.232

Low

1126769

Q5JE30
Protein disulfide oxidoreductase

1

0

High-throughput

0.232

Low

1126772

Q5JE59
2-oxoacid:ferredoxin oxidoreductases, alpha subunit

1

0

High-throughput

0.232

Low

1126773

Q5JE61
2-oxoacid:ferredoxin oxidoreductases, gamma subunit

1

0

High-throughput

0.232

Low

1126774

RNZ
Ribonuclease Z

1

0

High-throughput

0.232

Low

1126775

Q5JE90
Predicted AP endonuclease

1

0

High-throughput

0.232

Low

1126777

Q5JEM0
Predicted N6-adenine-specific DNA methylase

1

0

High-throughput

0.232

Low

1126778

Q5JEN6
Transcription regulator, ArsR family

1

0

High-throughput

0.232

Low

1126784

Q5JF43
Putative methylthioribose-1-phosphate isomerase

1

0

High-throughput

0.232

Low

1126790

PDAD
Pyruvoyl-dependent arginine decarboxylase

1

0

High-throughput

0.232

Low

1126791

Q5JFJ4
RecJ-like exonuclease, containing OB-fold nucleic acid-binding domains

1

0

High-throughput

0.232

Low

1126795

PDXS
Pyridoxal 5'-phosphate synthase subunit PdxS

1

0

High-throughput

0.232

Low

1126797

NADA
Quinolinate synthase

1

0

High-throughput

0.232

Low

1126802

Q5JG60
SAM-dependent methyltransferase, UbiE/COQ5 family

1

0

High-throughput

0.232

Low

1126804

Q5JGH2
Phospholipid-binding protein, PBP family

1

0

High-throughput

0.232

Low

1126807

RF1
Peptide chain release factor subunit 1

1

0

High-throughput

0.232

Low

1126812

Q5JGS9
Ferredoxin:NADP oxidoreductase, beta subunit

1

0

High-throughput

0.232

Low

1126814

Q5JGT9
Predicted transcription regulator, Lrp/AsnC family

1

0

High-throughput

0.232

Low

1126815

GCSPB
Probable glycine dehydrogenase

1

0

High-throughput

0.232

Low

1126816

RPIA
Ribose-5-phosphate isomerase A

1

0

High-throughput

0.232

Low

1126817

Q5JH40
Probable phosphate transport system regulator, fused to TrkA-C domain

1

0

High-throughput

0.232

Low

1126818

MPTA
GTP cyclohydrolase MptA

1

0

High-throughput

0.232

Low

1126823

Q5JHP7
DNA helicase

1

0

High-throughput

0.232

Low

1126826

Q5JHV9
4Fe-4S cluster-binding protein

1

0

High-throughput

0.232

Low

1126830

APGM
2,3-bisphosphoglycerate-independent phosphoglycerate mutase

1

0

High-throughput

0.232

Low

1126832

Q5JI60
Pyruvate fromate-lyase activating enzyme-related protein, radical SAM superfamily

1

0

High-throughput

0.232

Low

1126833

Q5JI71
3-hydroxy-3-methylglutaryl coenzyme A reductase

1

0

High-throughput

0.232

Low

1126838

Q5JIG4
Methylmalonyl-CoA mutase, N-terminus of large subunit

1

0

High-throughput

0.232

Low

1126841

Q5JII4
Carbamoyltransferase

1

0

High-throughput

0.232

Low

1126844

Q5JIJ6
Pyruvate:ferredoxin oxidoreductase, beta subunit

1

0

High-throughput

0.232

Low

1126845

Q5JIQ4
Predicted metal-dependent hydrolase

1

0

High-throughput

0.232

Low

1126847

PSA
Proteasome subunit alpha

1

0

High-throughput

0.232

Low

1126848

Q5JIV0
Ribosome maturation protein SDO1 homolog

1

0

High-throughput

0.232

Low

1126851

Q5JJ28
Cytidylyltransferase

1

0

High-throughput

0.232

Low

1126852

Q5JJ60
Predicted transcription regulator, DUF118 helix-turn-helix family

1

0

High-throughput

0.232

Low

1126860

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.232

Low

1126863

RS4E
Small ribosomal subunit protein eS4

1

0

High-throughput

0.232

Low

1246702

FLAB1
Flagellin B1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024