Protein: VATA
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (Vacuolar proton pump subunit A) [Cleaved into: Endonuclease PI-SceI (EC 3.1.-.-) (Sce VMA intein) (VMA1-derived endonuclease) (VDE)]

Gene: VATA, VMA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 222
UniProt ID: P17255

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0000329 - fungal-type vacuole membrane
GO:0003677 - DNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

555786

VATB
V-type proton ATPase subunit B

12

17

Small-scale

0.978

High

566553

VATD
V-type proton ATPase subunit D

7

10

Small-scale

0.960

High

566524

VATE
V-type proton ATPase subunit E

7

11

Small-scale

0.959

High

566550

VPP1
V-type proton ATPase subunit a, vacuolar isoform

12

12

Small-scale

0.758

High

566622

VATG
V-type proton ATPase subunit G

9

12

Small-scale

0.747

High

566607

VATH
V-type proton ATPase subunit H

7

8

Small-scale

0.738

High

566588

VATF
V-type proton ATPase subunit F

6

9

Small-scale

0.730

High

566544

VATC
V-type proton ATPase subunit C

6

13

Small-scale

0.727

High

566546

VA0D
V-type proton ATPase subunit d

5

8

Small-scale

0.712

High

566657

RAV2
Regulator of V-ATPase in vacuolar membrane protein 2

4

1

Small-scale

0.683

High

566555

VATL2
V-type proton ATPase subunit c'

4

7

Small-scale

0.676

High

420463

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

3

4

High-throughput

0.671

High

490255

HSP71
Heat shock protein SSA1

4

12

High-throughput

0.666

High

566618

RAV1
Regulator of V-ATPase in vacuolar membrane protein 1

3

7

Small-scale

0.662

High

566567

VPP2
V-type proton ATPase subunit a, Golgi isoform

3

12

Small-scale

0.647

High

365746

HSP82
ATP-dependent molecular chaperone HSP82

3

15

High-throughput

0.633

High

566517

VATA
V-type proton ATPase catalytic subunit A

1

16

High-throughput

0.618

High

566529

SIS1
Protein SIS1

2

6

High-throughput

0.601

High

566627

SKP1
Suppressor of kinetochore protein 1

2

1

Small-scale

0.601

High

566533

VATL1
V-type proton ATPase subunit c

2

7

Small-scale

0.594

High

566629

MCM6
DNA replication licensing factor MCM6

2

5

High-throughput

0.588

High

566527

VATO
V-type proton ATPase subunit c''

2

7

Small-scale

0.584

High

566659

RRP5
rRNA biogenesis protein RRP5

1

5

High-throughput

0.575

High

339422

CDK1
Cyclin-dependent kinase 1

2

7

High-throughput

0.571

High

543139

HSC82
ATP-dependent molecular chaperone HSC82

2

15

High-throughput

0.571

High

566651

GCN5
Histone acetyltransferase GCN5

2

5

High-throughput

0.549

High

566568

VRP1
Verprolin

2

6

High-throughput

0.537

High

566582

POP2
Poly(A) ribonuclease POP2

2

1

High-throughput

0.537

High

566587

XDJ1
DnaJ protein homolog XDJ1

2

5

High-throughput

0.537

High

566609

EMW1
Essential for maintenance of the cell wall protein 1

2

9

High-throughput

0.537

High

420430

RAD10
DNA repair protein RAD10

1

1

High-throughput

0.536

High

429617

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.536

High

521107

RAD50
DNA repair protein RAD50

1

4

High-throughput

0.536

High

566519

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

10

High-throughput

0.536

High

566525

DBF2
Cell cycle protein kinase DBF2

1

13

High-throughput

0.536

High

566537

CDC15
Cell division control protein 15

1

7

High-throughput

0.536

High

566545

KNS1
Dual specificity protein kinase KNS1

1

11

High-throughput

0.536

High

566554

ELM1
Serine/threonine-protein kinase ELM1

1

7

High-throughput

0.536

High

566599

RAD26
DNA repair and recombination protein RAD26

1

9

High-throughput

0.536

High

566635

BRE5
UBP3-associated protein BRE5

1

4

High-throughput

0.536

High

566644

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

7

High-throughput

0.536

High

566612

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

5

High-throughput

0.533

High

566575

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.513

High

566532

DMC1
Meiotic recombination protein DMC1

1

6

High-throughput

0.500

High

454548

TBA3
Tubulin alpha-3 chain

1

4

High-throughput

0.489

High

527212

HAP3
Transcriptional activator HAP3

1

1

High-throughput

0.489

High

566534

GID7
Glucose-induced degradation protein 7

1

9

High-throughput

0.489

High

566566

MAOM
NAD-dependent malic enzyme, mitochondrial

1

1

High-throughput

0.489

High

566573

SIF2
SIR4-interacting protein SIF2

1

11

High-throughput

0.489

High

566581

SPT8
Transcription factor SPT8

1

1

High-throughput

0.489

High

566600

NTA1
Protein N-terminal amidase

1

1

High-throughput

0.489

High

566601

UTP18
U3 small nucleolar RNA-associated protein 18

1

1

High-throughput

0.489

High

566602

NDC80
Kinetochore protein NDC80

1

5

High-throughput

0.489

High

566604

MET18
DNA repair/transcription protein MET18/MMS19

1

2

High-throughput

0.489

High

566613

SA155
SIT4-associating protein SAP155

1

5

High-throughput

0.489

High

566624

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

3

High-throughput

0.489

High

566663

UTP13
U3 small nucleolar RNA-associated protein 13

1

13

High-throughput

0.489

High

566669

PRP11
Pre-mRNA-splicing factor PRP11

1

2

High-throughput

0.489

High

566671

VPS13
Intermembrane lipid transfer protein VPS13

1

5

High-throughput

0.489

High

566686

IES3
Ino eighty subunit 3

1

3

High-throughput

0.489

High

375259

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

7

High-throughput

0.479

High

402876

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

4

Small-scale

0.479

High

410301

SC160
Protein SCP160

1

1

High-throughput

0.479

High

413284

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

477866

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.479

High

493129

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.479

High

513469

PPB
Repressible alkaline phosphatase

1

1

High-throughput

0.479

High

515164

SCH9
Serine/threonine-protein kinase SCH9

1

11

Small-scale

0.479

High

540354

BPT1
Bile pigment transporter 1

1

7

High-throughput

0.479

High

566523

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.479

High

566536

PHO91
Low-affinity phosphate transporter PHO91

1

3

High-throughput

0.479

High

566547

YBT1
ATP-dependent bile acid permease

1

4

High-throughput

0.479

High

566549

HOG1
Mitogen-activated protein kinase HOG1

1

9

High-throughput

0.479

High

566557

PRS6A
26S proteasome regulatory subunit 6A

1

7

High-throughput

0.479

High

566572

PFF1
Vacuolar membrane protease

1

3

High-throughput

0.479

High

566577

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.479

High

566584

TCPB
T-complex protein 1 subunit beta

1

15

High-throughput

0.479

High

566585

TCPG
T-complex protein 1 subunit gamma

1

12

High-throughput

0.479

High

566586

TCPZ
T-complex protein 1 subunit zeta

1

11

High-throughput

0.479

High

566589

DHH1
ATP-dependent RNA helicase DHH1

1

7

High-throughput

0.479

High

566593

KC13
Casein kinase I homolog 3

1

15

High-throughput

0.479

High

566596

VTC1
Vacuolar transporter chaperone complex subunit 1

1

6

High-throughput

0.479

High

566606

SYG1
Protein SYG1

1

3

High-throughput

0.479

High

566608

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

3

High-throughput

0.479

High

566610

TCPH
T-complex protein 1 subunit eta

1

12

High-throughput

0.479

High

566611

VTC2
Vacuolar transporter chaperone complex subunit 2

1

8

High-throughput

0.479

High

566615

MPS3
Spindle pole body assembly component MPS3

1

3

High-throughput

0.479

High

566616

VTC4
Vacuolar transporter chaperone complex subunit 4

1

8

High-throughput

0.479

High

566617

TCPQ
T-complex protein 1 subunit theta

1

11

High-throughput

0.479

High

566647

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

8

High-throughput

0.479

High

566650

TOM1
E3 ubiquitin-protein ligase TOM1

1

9

High-throughput

0.479

High

566652

RMD1
Sporulation protein RMD1

1

3

High-throughput

0.479

High

566656

RUVB1
RuvB-like protein 1

1

7

High-throughput

0.479

High

566658

VBA4
Vacuolar basic amino acid transporter 4

1

1

High-throughput

0.479

High

566664

TFC6
Transcription factor tau 91 kDa subunit

1

3

High-throughput

0.479

High

566666

CSC1
Calcium permeable stress-gated cation channel 1

1

4

High-throughput

0.479

High

566678

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

566680

SMF3
Iron transporter SMF3

1

1

High-throughput

0.479

High

566687

RUVB2
RuvB-like protein 2

1

7

High-throughput

0.479

High

566692

VCX1
Vacuolar calcium ion transporter

1

3

High-throughput

0.479

High

416277

SIR3
Regulatory protein SIR3

1

3

High-throughput

0.470

High

566683

YRA1
RNA annealing protein YRA1

1

0

Small-scale

0.458

High

566684

YVC1
Calcium channel YVC1

1

0

High-throughput

0.458

High

539943

EI2BA
Translation initiation factor eIF2B subunit alpha

1

3

High-throughput

0.457

High

541513

AMPL
Vacuolar aminopeptidase 1

1

1

High-throughput

0.457

High

566522

PP11
Serine/threonine-protein phosphatase PP1-1

1

3

High-throughput

0.457

High

566530

RV161
Reduced viability upon starvation protein 161

1

6

High-throughput

0.457

High

449893

HSP73
Heat shock protein SSA3

1

12

High-throughput

0.445

High

510174

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

519890

TCPA
T-complex protein 1 subunit alpha

1

13

High-throughput

0.445

High

561209

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

2

High-throughput

0.445

High

566521

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

2

High-throughput

0.445

High

566526

NPR1
Nitrogen permease reactivator protein

1

13

High-throughput

0.445

High

566542

MCM5
Minichromosome maintenance protein 5

1

7

High-throughput

0.445

High

566551

SMI1
Cell wall assembly regulator SMI1

1

2

High-throughput

0.445

High

566552

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

566579

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

566594

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.445

High

566598

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

566620

JSN1
Protein JSN1

1

3

High-throughput

0.445

High

566634

DBP6
ATP-dependent RNA helicase DBP6

1

2

High-throughput

0.445

High

566654

WDR59
Maintenance of telomere capping protein 5

1

13

High-throughput

0.445

High

141134

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

357862

RS17A
Small ribosomal subunit protein eS17A

1

4

High-throughput

0.437

High

382931

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

405407

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

406756

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.437

High

407703

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

425741

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

470842

RS22A
Small ribosomal subunit protein uS8A

1

4

High-throughput

0.437

High

471999

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

479901

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

480458

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

482060

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

524149

CAF20
Cap-associated protein CAF20

1

3

High-throughput

0.437

High

566518

PDI
Protein disulfide-isomerase

1

3

High-throughput

0.437

High

566520

IRA2
Inhibitory regulator protein IRA2

1

3

Small-scale

0.437

High

566531

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.437

High

566535

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.437

High

566539

PEX3
Peroxisomal biogenesis factor 3

1

2

High-throughput

0.437

High

566540

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

566541

BMH1
Protein BMH1

1

10

High-throughput

0.437

High

566556

SMY2
Protein SMY2

1

3

High-throughput

0.437

High

566559

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

566560

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

4

High-throughput

0.437

High

566562

SPT10
Protein SPT10

1

1

High-throughput

0.437

High

566563

SPT21
Protein SPT21

1

1

High-throughput

0.437

High

566564

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.437

High

566565

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

566569

GBLP
Small ribosomal subunit protein RACK1

1

11

High-throughput

0.437

High

566574

GID4
Vacuolar import and degradation protein 24

1

3

High-throughput

0.437

High

566576

AIM4
Altered inheritance of mitochondria protein 4

1

2

High-throughput

0.437

High

566578

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.437

High

566580

RPN10
26S proteasome regulatory subunit RPN10

1

6

High-throughput

0.437

High

566591

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

566603

TM108
Protein TMA108

1

5

High-throughput

0.437

High

566605

FIS1
Mitochondrial fission 1 protein

1

2

Small-scale

0.437

High

566614

RMD8
Sporulation protein RMD8

1

3

High-throughput

0.437

High

566619

MOG1
Nuclear import protein MOG1

1

3

High-throughput

0.437

High

566621

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.437

High

566623

TOM22
Mitochondrial import receptor subunit TOM22

1

2

High-throughput

0.437

High

566626

INP52
Polyphosphatidylinositol phosphatase INP52

1

3

High-throughput

0.437

High

566630

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

3

High-throughput

0.437

High

566631

VSB1
Vacuolar basic amino acid transporter VSB1

1

1

High-throughput

0.437

High

566642

SAM50
Sorting assembly machinery 50 kDa subunit

1

3

High-throughput

0.437

High

566643

NUM1
Nuclear migration protein NUM1

1

6

High-throughput

0.437

High

566645

RS15
Small ribosomal subunit protein uS19

1

4

High-throughput

0.437

High

566665

URN1
Pre-mRNA-splicing factor URN1

1

2

High-throughput

0.437

High

566672

SGO1
Shugoshin

1

3

High-throughput

0.437

High

566673

MCA1
Metacaspase-1

1

2

High-throughput

0.437

High

566674

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

566675

AP3D
AP-3 complex subunit delta

1

7

High-throughput

0.437

High

566681

RTC5
Restriction of telomere capping protein 5

1

1

High-throughput

0.437

High

566682

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.437

High

566690

VA0E
V-type proton ATPase subunit e

1

0

Small-scale

0.426

High

141821

RPN13
26S proteasome regulatory subunit RPN13

1

1

High-throughput

0.407

High

389842

VDAC1
Mitochondrial outer membrane protein porin 1

1

5

High-throughput

0.407

High

424989

DHE4
NADP-specific glutamate dehydrogenase 1

1

2

High-throughput

0.407

High

563919

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.407

High

566528

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

2

High-throughput

0.407

High

566538

LAC1
Ceramide synthase LAC1

1

4

High-throughput

0.407

High

566548

APE2
Aminopeptidase 2, mitochondrial

1

5

High-throughput

0.407

High

566558

MFT1
THO complex subunit MFT1

1

2

High-throughput

0.407

High

566561

SPT7
Transcriptional activator SPT7

1

4

High-throughput

0.407

High

566570

TAF5
Transcription initiation factor TFIID subunit 5

1

9

High-throughput

0.407

High

566571

SEA4
SEH-associated protein 4

1

2

High-throughput

0.407

High

566592

RV167
Reduced viability upon starvation protein 167

1

9

High-throughput

0.407

High

566597

MGDP1
Putative magnesium-dependent phosphatase YER134C

1

2

High-throughput

0.407

High

566628

NIF3
NGG1-interacting factor 3

1

1

High-throughput

0.407

High

566632

ZNG1
Zinc-regulated GTPase metalloprotein activator 1

1

2

High-throughput

0.407

High

566633

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

1

High-throughput

0.407

High

566636

HCH1
Hsp90 co-chaperone HCH1

1

3

High-throughput

0.407

High

566638

RM22
Large ribosomal subunit protein uL22m

1

2

High-throughput

0.407

High

566639

NOP13
Nucleolar protein 13

1

7

High-throughput

0.407

High

566646

ADA2
Transcriptional adapter 2

1

2

High-throughput

0.407

High

566648

SVL3
Styryl dye vacuolar localization protein 3

1

2

High-throughput

0.407

High

566653

ACL4
Assembly chaperone of RPL4

1

1

High-throughput

0.407

High

566661

BCH1
Protein BCH1

1

2

High-throughput

0.407

High

566662

YL287
Uncharacterized protein YLR287C

1

2

High-throughput

0.407

High

566667

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

6

High-throughput

0.407

High

566668

SSK1
Osmolarity two-component system protein SSK1

1

5

High-throughput

0.407

High

566676

OXR1
Oxidation resistance protein 1

1

10

High-throughput

0.407

High

566679

HFI1
Transcriptional coactivator HFI1/ADA1

1

2

High-throughput

0.407

High

566641

PFD4
Prefoldin subunit 4

2

0

High-throughput

0.307

High

566595

YEC3
Uncharacterized protein YEL023C

1

0

High-throughput

0.269

Low

566677

YIG1
Protein YIG1

1

0

High-throughput

0.269

Low

566685

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.261

Low

411159

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.249

Low

566637

PDR17
Phosphatidylinositol transfer protein PDR17

1

0

High-throughput

0.249

Low

566655

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

566688

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.249

Low

566543

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.232

Low

566583

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.232

Low

566590

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

566625

SPT20
Transcription factor SPT20

1

0

High-throughput

0.232

Low

566640

MDG1
Signal transduction protein MDG1

1

0

High-throughput

0.232

Low

566649

YMY9
Glucose-6-phosphate 1-epimerase

1

0

High-throughput

0.232

Low

566660

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.232

Low

566670

CYK3
Cytokinesis protein 3

1

0

High-throughput

0.232

Low

566689

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low

566691

DET1
Broad-range acid phosphatase DET1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024