Protein: TCPB
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)

Gene: TCPB, CCT2
Organism: Saccharomyces cerevisiae S288C
Interactions: 236
UniProt ID: P39076

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005832 - chaperonin-containing T-complex
GO:0006457 - protein folding
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

760608

TCPG
T-complex protein 1 subunit gamma

5

19

Small-scale

0.898

High

519941

TCPA
T-complex protein 1 subunit alpha

3

17

Small-scale

0.857

High

760609

TCPD
T-complex protein 1 subunit delta

3

19

High-throughput

0.830

High

760634

TCPH
T-complex protein 1 subunit eta

2

19

High-throughput

0.789

High

760610

TCPZ
T-complex protein 1 subunit zeta

2

19

High-throughput

0.754

High

594321

PP11
Serine/threonine-protein phosphatase PP1-1

4

20

High-throughput

0.697

High

760668

2ABA
Protein phosphatase PP2A regulatory subunit B

3

20

High-throughput

0.667

High

760718

CMR1
DNA damage-binding protein CMR1

3

20

High-throughput

0.656

High

760626

TCPE
T-complex protein 1 subunit epsilon

1

19

High-throughput

0.618

High

760644

TCPQ
T-complex protein 1 subunit theta

1

19

High-throughput

0.618

High

640840

CDC20
APC/C activator protein CDC20

2

20

Small-scale

0.611

High

760624

VID27
Vacuolar import and degradation protein 27

2

3

High-throughput

0.611

High

760659

CDH1
APC/C activator protein CDH1

2

20

Small-scale

0.611

High

760706

PLP2
Phosducin-like protein 2

2

20

High-throughput

0.611

High

760715

WTM1
Transcriptional modulator WTM1

2

3

High-throughput

0.611

High

511337

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.584

High

543747

HSC82
ATP-dependent molecular chaperone HSC82

2

16

High-throughput

0.584

High

760649

HGH1
Protein HGH1

2

3

Small-scale

0.584

High

744616

TAF5
Transcription initiation factor TFIID subunit 5

2

20

High-throughput

0.574

High

760656

HOS2
Probable histone deacetylase HOS2

2

20

High-throughput

0.571

High

745987

ATG8
Autophagy-related protein 8

1

20

Small-scale

0.561

High

733375

CAF4
CCR4-associated factor 4

2

20

High-throughput

0.558

High

491246

HSP71
Heat shock protein SSA1

2

13

High-throughput

0.552

High

760655

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.546

High

539352

KSS1
Mitogen-activated protein kinase KSS1

1

16

High-throughput

0.536

High

579421

GBB
Guanine nucleotide-binding protein subunit beta

1

20

High-throughput

0.536

High

597837

PWP1
Periodic tryptophan protein 1

1

20

High-throughput

0.536

High

688116

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

20

High-throughput

0.536

High

693709

IME2
Meiosis induction protein kinase IME2/SME1

1

15

High-throughput

0.536

High

699038

PP2A4
Serine/threonine-protein phosphatase PP2A-like PPG1

1

20

High-throughput

0.536

High

730457

PTK1
Serine/threonine-protein kinase PTK1/STK1

1

15

High-throughput

0.536

High

760611

PEX7
Peroxisomal targeting signal 2 receptor

1

20

High-throughput

0.536

High

760662

BRE5
UBP3-associated protein BRE5

1

6

High-throughput

0.536

High

760672

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

7

High-throughput

0.536

High

760705

NEW1
[NU+] prion formation protein 1

1

1

High-throughput

0.536

High

760702

ESA1
Histone acetyltransferase ESA1

2

2

Small-scale

0.534

High

687379

EF2
Elongation factor 2

2

9

Small-scale

0.533

High

760638

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

11

High-throughput

0.533

High

356478

H4
Histone H4

2

3

High-throughput

0.521

High

760667

H3
Histone H3

2

9

High-throughput

0.521

High

760646

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.513

High

450051

HSP73
Heat shock protein SSA3

1

13

High-throughput

0.500

High

605350

HSP74
Heat shock protein SSA4

1

13

High-throughput

0.500

High

693016

RPD3
Histone deacetylase RPD3

1

20

Small-scale

0.500

High

707087

DCA13
Protein SOF1

1

20

High-throughput

0.489

High

715328

SPT7
Transcriptional activator SPT7

1

8

High-throughput

0.489

High

746092

MOH1
Protein yippee-like MOH1

1

2

High-throughput

0.489

High

757414

SPT8
Transcription factor SPT8

1

3

High-throughput

0.489

High

760621

UTP7
U3 small nucleolar RNA-associated protein 7

1

20

High-throughput

0.489

High

760630

COPB2
Coatomer subunit beta'

1

20

High-throughput

0.489

High

760633

PFS2
Polyadenylation factor subunit 2

1

20

High-throughput

0.489

High

760707

RAD28
Radiation-sensitive protein 28

1

20

High-throughput

0.489

High

537419

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

554648

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

366297

HSP82
ATP-dependent molecular chaperone HSP82

1

16

High-throughput

0.479

High

407053

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.479

High

454326

TBA1
Tubulin alpha-1 chain

1

20

High-throughput

0.479

High

454605

TBA3
Tubulin alpha-3 chain

1

20

High-throughput

0.479

High

556055

VATB
V-type proton ATPase subunit B

1

10

High-throughput

0.479

High

566584

VATA
V-type proton ATPase catalytic subunit A

1

15

High-throughput

0.479

High

618771

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

20

High-throughput

0.479

High

628058

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

631881

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

638751

SPB4
ATP-dependent rRNA helicase SPB4

1

5

High-throughput

0.479

High

664824

BMH1
Protein BMH1

1

3

High-throughput

0.479

High

680709

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

688246

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

700894

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

728242

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

742798

GBLP
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.479

High

745541

MAP2
Methionine aminopeptidase 2

1

7

High-throughput

0.479

High

752346

ARP1
Centractin

1

20

High-throughput

0.479

High

760615

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

760651

VATG
V-type proton ATPase subunit G

1

3

High-throughput

0.479

High

760677

TOM1
E3 ubiquitin-protein ligase TOM1

1

14

High-throughput

0.479

High

760681

PLP1
Phosducin-like protein 1

1

18

High-throughput

0.479

High

760682

DHR1
Probable ATP-dependent RNA helicase DHR1

1

4

High-throughput

0.479

High

760687

YMW4
Uncharacterized protein YMR074C

1

8

High-throughput

0.479

High

760701

SGO1
Shugoshin

1

3

High-throughput

0.479

High

760720

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

334933

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

6

High-throughput

0.457

High

378347

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.457

High

657066

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

2

High-throughput

0.457

High

660912

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

2

High-throughput

0.457

High

334690

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

6

High-throughput

0.445

High

340676

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.445

High

368066

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

402952

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

4

High-throughput

0.445

High

410226

UBC2
Ubiquitin-conjugating enzyme E2 2

1

1

High-throughput

0.445

High

478199

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.445

High

493985

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

523271

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

10

High-throughput

0.445

High

532822

MSI1
Chromatin assembly factor 1 subunit p50

1

20

High-throughput

0.445

High

539468

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

2

High-throughput

0.445

High

593637

DBP4
ATP-dependent RNA helicase HCA4

1

6

High-throughput

0.445

High

605534

DBF2
Cell cycle protein kinase DBF2

1

11

High-throughput

0.445

High

688717

AAR2
A1 cistron-splicing factor AAR2

1

5

High-throughput

0.445

High

699158

RAD5
DNA repair protein RAD5

1

3

High-throughput

0.445

High

730510

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

14

High-throughput

0.445

High

730631

EF1G2
Elongation factor 1-gamma 2

1

1

High-throughput

0.445

High

730696

DHR2
Probable ATP-dependent RNA helicase DHR2

1

1

High-throughput

0.445

High

759219

END3
Actin cytoskeleton-regulatory complex protein END3

1

2

High-throughput

0.445

High

760612

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.445

High

760618

ARB1
ABC transporter ATP-binding protein ARB1

1

1

High-throughput

0.445

High

760623

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

760640

AIP1
Actin-interacting protein 1

1

20

High-throughput

0.445

High

760643

MTR4
ATP-dependent RNA helicase DOB1

1

2

High-throughput

0.445

High

760647

GPN1
GPN-loop GTPase 1

1

2

High-throughput

0.445

High

760650

GYP7
GTPase-activating protein GYP7

1

1

High-throughput

0.445

High

760654

UBC11
Ubiquitin-conjugating enzyme E2-18 kDa

1

2

High-throughput

0.445

High

760657

INO80
Chromatin-remodeling ATPase INO80

1

3

High-throughput

0.445

High

760666

ACT
Actin

1

20

Small-scale

0.445

High

760670

ACAC
Acetyl-CoA carboxylase

1

2

High-throughput

0.445

High

760671

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

18

High-throughput

0.445

High

760676

ESP1
Separin

1

2

High-throughput

0.445

High

760716

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

1

High-throughput

0.445

High

383150

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

405625

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

471059

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

480106

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

606647

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.437

High

618835

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

20

High-throughput

0.437

High

634604

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.437

High

662242

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

700413

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

716240

SPT10
Protein SPT10

1

1

High-throughput

0.437

High

716426

SPT21
Protein SPT21

1

2

High-throughput

0.437

High

730800

CENPA
Histone H3-like centromeric protein CSE4

1

9

High-throughput

0.437

High

755767

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

19

Small-scale

0.437

High

760613

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

760635

UTP10
U3 small nucleolar RNA-associated protein 10

1

3

High-throughput

0.437

High

760642

MDV1
Mitochondrial division protein 1

1

20

High-throughput

0.437

High

760669

NUM1
Nuclear migration protein NUM1

1

13

High-throughput

0.437

High

760691

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

760692

TFC6
Transcription factor tau 91 kDa subunit

1

3

High-throughput

0.437

High

340142

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

341067

INV2
Invertase 2

1

0

High-throughput

0.426

High

341096

CBPY
Carboxypeptidase Y

1

0

High-throughput

0.426

High

341715

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.426

High

420126

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.426

High

423459

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.426

High

534767

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.426

High

539897

RAD4
DNA repair protein RAD4

1

0

High-throughput

0.426

High

624267

AP2
AP-1-like transcription factor YAP2

1

0

High-throughput

0.426

High

629423

PUF4
Pumilio homology domain family member 4

1

0

High-throughput

0.426

High

657186

OPLA
5-oxoprolinase

1

0

High-throughput

0.426

High

676054

XPO1
Exportin-1

1

0

High-throughput

0.426

High

680032

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

High-throughput

0.426

High

688687

TREA
Cytosolic neutral trehalase

1

0

High-throughput

0.426

High

733015

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.426

High

741415

PAM1
Protein PAM1

1

0

High-throughput

0.426

High

754336

GIC1
GTPase-interacting component 1

1

0

High-throughput

0.426

High

759081

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.426

High

760614

MTW1
Kinetochore-associated protein MTW1

1

0

High-throughput

0.426

High

760617

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.426

High

760619

VHR2
Transcription factor VHR2

1

0

High-throughput

0.426

High

760625

ATG3
Autophagy-related protein 3

1

0

High-throughput

0.426

High

760636

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.426

High

760639

IGD1
Inhibitor of glycogen debranching 1

1

0

High-throughput

0.426

High

760645

YAE1
Protein YAE1

1

0

High-throughput

0.426

High

760653

YG51
Uncharacterized protein YGR237C

1

0

High-throughput

0.426

High

760664

NSG2
Protein NSG2

1

0

High-throughput

0.426

High

760679

CWC21
Pre-mRNA-splicing factor CWC21

1

0

High-throughput

0.426

High

760683

SEG1
Eisosome protein SEG1

1

0

High-throughput

0.426

High

760684

GYL1
Probable GTPase-activating protein GYL1

1

0

High-throughput

0.426

High

760696

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.426

High

760698

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.426

High

760699

PML1
Pre-mRNA leakage protein 1

1

0

High-throughput

0.426

High

760704

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.426

High

760713

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.426

High

760714

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.426

High

760717

STB3
Protein STB3

1

0

High-throughput

0.426

High

343123

THDH
Threonine dehydratase, mitochondrial

1

1

High-throughput

0.407

High

375394

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.407

High

526845

DPOLA
DNA polymerase alpha catalytic subunit A

1

3

High-throughput

0.407

High

527217

HAP3
Transcriptional activator HAP3

1

1

High-throughput

0.407

High

528326

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.407

High

584160

ACON
Aconitate hydratase, mitochondrial

1

2

High-throughput

0.407

High

586405

PRP6
Pre-mRNA-splicing factor 6

1

7

High-throughput

0.407

High

629474

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

1

High-throughput

0.407

High

715683

TAF14
Transcription initiation factor TFIID subunit 14

1

1

High-throughput

0.407

High

755417

TRA1
Transcription-associated protein 1

1

2

High-throughput

0.407

High

758528

SEC31
Protein transport protein SEC31

1

20

High-throughput

0.407

High

760616

RPN3
26S proteasome regulatory subunit RPN3

1

1

High-throughput

0.407

High

760627

NU159
Nucleoporin NUP159

1

1

High-throughput

0.407

High

760632

YN60
Uncharacterized membrane protein YNL320W

1

3

High-throughput

0.407

High

760652

LYS4
Homoaconitase, mitochondrial

1

2

High-throughput

0.407

High

760660

COPA
Coatomer subunit alpha

1

20

High-throughput

0.407

High

760661

PRA1
Prenylated Rab acceptor 1

1

1

High-throughput

0.407

High

760674

ARL3
ADP-ribosylation factor-like protein 3

1

5

High-throughput

0.407

High

760675

SPP1
COMPASS component SPP1

1

1

High-throughput

0.407

High

760678

JIP4
Uncharacterized protein JIP4

1

1

High-throughput

0.407

High

760686

DPB4
DNA polymerase epsilon subunit D

1

1

High-throughput

0.407

High

760688

RRP5
rRNA biogenesis protein RRP5

1

7

High-throughput

0.407

High

760689

UTP21
U3 small nucleolar RNA-associated protein 21

1

20

High-throughput

0.407

High

760694

CORO
Coronin-like protein

1

20

High-throughput

0.407

High

760695

UTP4
U3 small nucleolar RNA-associated protein 4

1

20

High-throughput

0.407

High

760703

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.407

High

760708

AP1G1
AP-1 complex subunit gamma-1

1

2

High-throughput

0.407

High

760711

SCC1
Sister chromatid cohesion protein 1

1

4

High-throughput

0.407

High

760712

LEU9
2-isopropylmalate synthase 2, mitochondrial

1

2

High-throughput

0.407

High

760719

SET6
Potential protein lysine methyltransferase SET6

1

3

High-throughput

0.407

High

760721

RS22B
Small ribosomal subunit protein uS8B

1

2

High-throughput

0.407

High

760693

ESF1
Pre-rRNA-processing protein ESF1

2

0

High-throughput

0.307

High

760697

THI3
Thiamine metabolism regulatory protein THI3

2

0

High-throughput

0.307

High

760629

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.298

High

561949

SEN2
tRNA-splicing endonuclease subunit SEN2

1

0

High-throughput

0.279

Low

760631

BNI1
Protein BNI1

1

0

High-throughput

0.261

Low

410798

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.261

Low

294123

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.232

Low

546739

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.232

Low

568939

GABAT
4-aminobutyrate aminotransferase

1

0

High-throughput

0.232

Low

572043

CLC1
Clathrin light chain

1

0

High-throughput

0.232

Low

604338

AEP2
ATPase expression protein 2, mitochondrial

1

0

High-throughput

0.232

Low

655125

NAM9
Small ribosomal subunit protein uS4m

1

0

High-throughput

0.232

Low

693540

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.232

Low

706140

MFT1
THO complex subunit MFT1

1

0

High-throughput

0.232

Low

710169

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.232

Low

745037

AP3M
AP-3 complex subunit mu

1

0

High-throughput

0.232

Low

757269

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

760620

ICP55
Intermediate cleaving peptidase 55

1

0

High-throughput

0.232

Low

760622

IES5
Ino eighty subunit 5

1

0

High-throughput

0.232

Low

760628

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low

760637

IES1
Ino eighty subunit 1

1

0

High-throughput

0.232

Low

760641

GON7
EKC/KEOPS complex subunit GON7

1

0

High-throughput

0.232

Low

760648

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.232

Low

760658

GET1
Golgi to ER traffic protein 1

1

0

High-throughput

0.232

Low

760663

YNT3
Uncharacterized protein YNL193W

1

0

High-throughput

0.232

Low

760665

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.232

Low

760673

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.232

Low

760680

VPS71
Vacuolar protein sorting-associated protein 71

1

0

High-throughput

0.232

Low

760685

YMJ0
Putative uncharacterized protein YML090W

1

0

High-throughput

0.232

Low

760690

RRG8
Required for respiratory growth protein 8, mitochondrial

1

0

High-throughput

0.232

Low

760700

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.232

Low

760709

THP3
Protein THP3

1

0

High-throughput

0.232

Low

760710

CFT2
Cleavage factor two protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024