Protein: KCNH2
Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (H-ERG) (hERG-1) (hERG1) (Voltage-gated potassium channel subunit Kv11.1)

Gene: KCNH2
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q12809

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0003064 - regulation of heart rate by hormone
GO:0005242 - inward rectifier potassium channel activity
GO:0005249 - voltage-gated potassium channel activity
GO:0005251 - delayed rectifier potassium channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1017011

KCNH2
Potassium voltage-gated channel subfamily H member 2

4

15

Small-scale

0.896

High

1017033

KCNH7
Potassium voltage-gated channel subfamily H member 7

1

16

High-throughput

0.691

High

431785

HS90A
Heat shock protein HSP 90-alpha

4

2

Small-scale

0.683

High

548162

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

2

Small-scale

0.618

High

1017035

KCND3
Potassium voltage-gated channel subfamily D member 3

1

3

Small-scale

0.618

High

1017029

FRMD8
FERM domain-containing protein 8

2

1

High-throughput

0.606

High

503982

HSP7C
Heat shock cognate 71 kDa protein

2

2

Small-scale

0.601

High

1017019

RN207
RING finger protein 207

2

2

Small-scale

0.584

High

1017025

NED4L
E3 ubiquitin-protein ligase NEDD4-like

2

3

Small-scale

0.584

High

1017036

CHIP
E3 ubiquitin-protein ligase CHIP

2

2

Small-scale

0.584

High

1017026

PASK
PAS domain-containing serine/threonine-protein kinase

1

11

Small-scale

0.579

High

909492

1433E
14-3-3 protein epsilon

1

8

Small-scale

0.573

High

1017031

TARA
TRIO and F-actin-binding protein

1

9

Small-scale

0.573

High

654291

CALX
Calnexin

2

1

Small-scale

0.549

High

1017012

CUL1
Cullin-1

1

1

High-throughput

0.536

High

1017020

AN13D
Ankyrin repeat domain-containing protein 13D

1

2

High-throughput

0.536

High

1017024

MIB2
E3 ubiquitin-protein ligase MIB2

1

5

High-throughput

0.536

High

1017032

JPH1
Junctophilin-1

1

2

High-throughput

0.536

High

714200

HSP74
Heat shock 70 kDa protein 4

2

3

Small-scale

0.533

High

914036

RB11A
Ras-related protein Rab-11A

1

0

Small-scale

0.517

High

681415

DNJA1
DnaJ homolog subfamily A member 1

1

1

Small-scale

0.515

High

1017027

SMAD5
Mothers against decapentaplegic homolog 5

1

0

High-throughput

0.513

High

1017016

Q6ICP4
ARHH protein

1

0

High-throughput

0.494

High

323716

BAG2
BAG family molecular chaperone regulator 2

1

0

Small-scale

0.493

High

384736

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

653572

CALR
Calreticulin

1

1

Small-scale

0.479

High

881086

CAV3
Caveolin-3

1

4

Small-scale

0.479

High

1017023

RFFL
E3 ubiquitin-protein ligase rififylin

1

3

Small-scale

0.479

High

1017013

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

Small-scale

0.470

High

1017015

AG10B
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

0

Small-scale

0.458

High

1017021

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.458

High

974784

CAV1
Caveolin-1

1

4

Small-scale

0.457

High

306138

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.445

High

1017030

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

2

High-throughput

0.445

High

1017022

RN139
E3 ubiquitin-protein ligase RNF139

1

2

Small-scale

0.437

High

261814

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.282

High

1017017

CDC73
Parafibromin

1

0

High-throughput

0.282

High

1017014

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

1017018

KLD10
Kelch domain-containing protein 10

1

0

High-throughput

0.279

Low

1017034

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.279

Low

684670

STIP1
Stress-induced-phosphoprotein 1

1

0

Small-scale

0.269

Low

1017028

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024