Protein: ESC
Polycomb protein esc (Protein extra sex combs)

Gene: ESC
Organism: Drosophila melanogaster
Interactions: 33
UniProt ID: Q24338

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005700 - polytene chromosome
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

785624

EZ
Histone-lysine N-methyltransferase E(z)

25

20

Small-scale

0.991

High

1097599

SUZ12
Polycomb protein Su(z)12

10

10

Small-scale

0.970

High

1097595

CAF1
Chromatin assembly factor 1 p55 subunit

9

20

Small-scale

0.967

High

1097593

ESC
Polycomb protein esc

3

18

Small-scale

0.886

High

1097594

PCL
Polycomb protein Pcl

6

20

Small-scale

0.729

High

1097598

HDAC1
Histone deacetylase HDAC1

5

20

Small-scale

0.727

High

356077

H3
Histone H3

2

16

Small-scale

0.629

High

1097607

Q9VKD5
Escl, isoform A

1

19

Small-scale

0.618

High

1097597

PHO
Polycomb protein PHO

2

10

Small-scale

0.584

High

1097611

Q9VT00
Jumonji, AT rich interactive domain 2

2

6

Small-scale

0.571

High

780463

CORTO
Centrosomal and chromosomal factor

1

0

Small-scale

0.561

High

639962

PC
Polycomb group protein Pc

2

18

Small-scale

0.552

High

1096186

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

1097602

Q9VDF0
Hematopoietically expressed homeobox

1

10

High-throughput

0.541

High

1097606

Q9VJ27
Uncharacterized protein, isoform A

1

2

High-throughput

0.541

High

1097601

Q9VAI8
Doublesex-Mab related 99B

1

0

High-throughput

0.518

High

836515

TAF12
Transcription initiation factor TFIID subunit 12

1

3

High-throughput

0.508

High

668250

ABDA
Homeobox protein abdominal-A

1

5

High-throughput

0.481

High

949997

UBX
Homeotic protein ultrabithorax

1

6

High-throughput

0.481

High

1097596

Q7KUL4
Intermediate neuroblasts defective

1

4

High-throughput

0.481

High

764498

PHP
Polyhomeotic-proximal chromatin protein

1

20

Small-scale

0.479

High

950431

H2A
Histone H2A

1

12

Small-scale

0.479

High

996055

GAGA
Transcription activator GAGA

1

6

Small-scale

0.479

High

1097603

SAP18
Histone deacetylase complex subunit SAP18

1

1

Small-scale

0.479

High

1097604

SCM
Polycomb protein Scm

1

10

Small-scale

0.479

High

1097608

PIWI
Protein piwi

1

4

Small-scale

0.479

High

1097610

Q9VSZ3
LD31045p

1

9

Small-scale

0.479

High

1097609

Q9VPG7
G protein RhoBTB

1

18

High-throughput

0.464

High

332120

O96620
Intermediate neuroblasts defective protein

1

4

High-throughput

0.457

High

1097612

Q9W215
GEO03726p1

1

5

High-throughput

0.445

High

1097600

WARTS
Serine/threonine-protein kinase Warts

1

8

Small-scale

0.437

High

1097605

Q9VHT8
RE26525p

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024