Protein: DESI1
Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Palmitoyl protein thioesterase DESI1) (EC 3.1.2.22) (S-depalmitoylase DESI1)

Gene: DESI1
Organism: Mus musculus
Interactions: 28
UniProt ID: Q9CQT7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0006611 - protein export from nucleus
GO:0008474 - palmitoyl-(protein) hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1423740

DESI1
Desumoylating isopeptidase 1

1

6

Small-scale

0.573

High

1296683

ZBT46
Zinc finger and BTB domain-containing protein 46

1

1

Small-scale

0.506

High

508945

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

4

Small-scale

0.457

High

937193

ADK
Adenosine kinase

1

1

Small-scale

0.457

High

313385

RBM3
RNA-binding protein 3

1

0

Small-scale

0.438

High

379821

B2MG
Beta-2-microglobulin

1

0

Small-scale

0.438

High

576870

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.438

High

609551

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.438

High

946392

BTBD1
BTB/POZ domain-containing protein 1

1

0

Small-scale

0.438

High

994455

PHB1
Prohibitin 1

1

0

Small-scale

0.438

High

996084

RACK1
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.438

High

1017373

H33
Histone H3.3

1

0

Small-scale

0.438

High

1021404

SLBP
Histone RNA hairpin-binding protein

1

0

Small-scale

0.438

High

1243801

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

0

Small-scale

0.438

High

1317250

NCKPL
Nck-associated protein 1-like

1

0

Small-scale

0.438

High

1354014

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

Small-scale

0.438

High

1423741

SERB1
SERPINE1 mRNA-binding protein 1

1

0

Small-scale

0.438

High

1423744

GLTP
Glycolipid transfer protein

1

0

Small-scale

0.438

High

615324

BASI
Basigin

1

0

Small-scale

0.238

Low

1200636

Q545X8
40S ribosomal protein S4

1

0

Small-scale

0.238

Low

1210572

SFT2A
Vesicle transport protein SFT2A

1

0

Small-scale

0.238

Low

1317152

Q8JZQ1
Mitochondrial import inner membrane translocase subunit TIM23

1

0

Small-scale

0.238

Low

1317303

Q8K2E5
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

0

Small-scale

0.238

Low

1341395

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

Small-scale

0.238

Low

1423678

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

Small-scale

0.238

Low

1423742

CISY
Citrate synthase, mitochondrial

1

0

Small-scale

0.238

Low

1423743

ZDHC4
Palmitoyltransferase ZDHHC4

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025