Protein: APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1 (Ap4A phosphorylase 1) (EC 2.7.7.53) (ADP-sulfurylase) (EC 2.7.7.5) (ATP adenylyltransferase) (Diadenosine tetraphosphate alpha,beta-phosphorylase (ADP-forming))]

Gene: APA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P16550

Gene Ontology (top 5):
GO:0003877 - ATP:ADP adenylyltransferase activity
GO:0004780 - sulfate adenylyltransferase (ADP) activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

543129

HSC82
ATP-dependent molecular chaperone HSC82

4

2

High-throughput

0.666

High

493117

HSP72
Heat shock protein SSA2

3

1

High-throughput

0.624

High

365735

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.571

High

490239

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.571

High

561249

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

340000

KPYK1
Pyruvate kinase 1

2

0

High-throughput

0.547

High

334883

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

2

2

High-throughput

0.521

High

561251

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

0

High-throughput

0.513

High

561255

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

561208

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

334428

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.479

High

334605

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.479

High

561214

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

561219

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

561223

ZUO1
Zuotin

1

1

Small-scale

0.479

High

561260

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

561267

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

2

High-throughput

0.479

High

561270

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

561258

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.460

High

561215

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

561217

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.458

High

561222

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

561225

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

561230

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

561237

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

561238

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

561242

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

561253

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

561256

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

Small-scale

0.458

High

561261

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

561263

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

561268

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

561269

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

561271

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

341906

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.445

High

439961

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.445

High

510157

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

555784

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

560896

EF3A
Elongation factor 3A

1

2

High-throughput

0.445

High

561209

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

561213

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.445

High

561243

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

561248

GCN20
Protein GCN20

1

1

High-throughput

0.445

High

561257

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.445

High

333683

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

356225

H4
Histone H4

1

0

High-throughput

0.426

High

360725

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

367698

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

389046

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

406752

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

410889

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.426

High

421568

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

423509

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.426

High

424327

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

440854

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.426

High

450275

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

454160

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

498426

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.426

High

534689

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.426

High

561207

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.426

High

561210

UPP
Uracil phosphoribosyltransferase

1

0

High-throughput

0.426

High

561218

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

561224

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.426

High

561227

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.426

High

561231

NDK
Nucleoside diphosphate kinase

1

0

High-throughput

0.426

High

561233

AAP1
Alanine/arginine aminopeptidase

1

0

High-throughput

0.426

High

561234

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.426

High

561235

SYG
Glycine--tRNA ligase 1, mitochondrial

1

0

High-throughput

0.426

High

561239

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

0

High-throughput

0.426

High

561241

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

561247

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

561250

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

561252

MSN5
Protein MSN5

1

0

High-throughput

0.426

High

561259

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.426

High

561262

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

561264

TRM3
tRNA

1

0

High-throughput

0.426

High

561266

MDN1
Midasin

1

0

High-throughput

0.426

High

561229

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.407

High

561246

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.407

High

561254

COPA
Coatomer subunit alpha

1

1

High-throughput

0.407

High

343522

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.249

Low

561236

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

561244

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

410747

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.232

Low

426359

PMM
Phosphomannomutase

1

0

High-throughput

0.232

Low

540018

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

561211

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

561212

SAR1
Small COPII coat GTPase SAR1

1

0

High-throughput

0.232

Low

561216

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.232

Low

561220

COPG
Coatomer subunit gamma

1

0

High-throughput

0.232

Low

561221

EF2
Elongation factor 2

1

0

High-throughput

0.232

Low

561226

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low

561228

CSE1
Importin alpha re-exporter

1

0

High-throughput

0.232

Low

561232

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.232

Low

561240

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.232

Low

561245

COPB
Coatomer subunit beta

1

0

High-throughput

0.232

Low

561265

VPS13
Intermembrane lipid transfer protein VPS13

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024