Protein: ILV3
Dihydroxy-acid dehydratase, mitochondrial (DAD) (EC 4.2.1.9)

Gene: ILV3
Organism: Saccharomyces cerevisiae S288C
Interactions: 101
UniProt ID: P39522

Gene Ontology (top 5):
GO:0004160 - dihydroxy-acid dehydratase activity
GO:0005739 - mitochondrion
GO:0008652 - amino acid biosynthetic process
GO:0009082 - branched-chain amino acid biosynthetic process
GO:0009097 - isoleucine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

762087

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

2

High-throughput

0.618

High

478206

HSP77
Import motor subunit, mitochondrial

2

1

High-throughput

0.584

High

543758

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

342022

ATPB
ATP synthase subunit beta, mitochondrial

2

1

High-throughput

0.571

High

584163

ACON
Aconitate hydratase, mitochondrial

2

1

High-throughput

0.571

High

757105

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

2

0

Small-scale

0.559

High

588088

HSP60
Heat shock protein 60, mitochondrial

2

0

High-throughput

0.547

High

366307

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.521

High

762103

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

762117

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.479

High

423609

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

1

High-throughput

0.479

High

520835

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.479

High

560341

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

1

2

High-throughput

0.479

High

581293

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.479

High

596642

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

705189

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

762104

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

336724

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

410802

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

419698

RHO1
GTP-binding protein RHO1

1

0

High-throughput

0.458

High

427243

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

452996

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

558627

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

567971

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

601438

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.458

High

612944

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

619737

TOM40
Mitochondrial import receptor subunit TOM40

1

0

High-throughput

0.458

High

630802

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

635002

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.458

High

641317

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

0

High-throughput

0.458

High

650217

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.458

High

653067

COQ8
Atypical kinase COQ8, mitochondrial

1

0

High-throughput

0.458

High

657067

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

0

High-throughput

0.458

High

662259

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

690671

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

699319

NFU1
NifU-like protein, mitochondrial

1

0

Small-scale

0.458

High

699893

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

700042

PREP
Presequence protease, mitochondrial

1

0

High-throughput

0.458

High

710637

PRX1
Peroxiredoxin PRX1, mitochondrial

1

0

High-throughput

0.458

High

732900

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

733658

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

737167

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

750707

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.458

High

755042

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.458

High

762089

BOL3
BolA-like protein 3

1

0

Small-scale

0.458

High

762092

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

0

High-throughput

0.458

High

762094

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

762096

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

762097

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

762100

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

762102

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

762105

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.458

High

762107

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

762111

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

762116

ETFA
Probable electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

493998

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

762090

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

680716

HS104
Heat shock protein 104

1

1

Small-scale

0.437

High

762110

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

762115

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

334696

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

360884

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

368075

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

424527

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

454331

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

562386

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.426

High

604556

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.426

High

707859

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.426

High

730979

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.426

High

333792

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.407

High

491262

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

556062

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

693303

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.407

High

753809

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.407

High

757418

SPT8
Transcription factor SPT8

1

0

High-throughput

0.279

Low

524309

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

628066

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

688249

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

701435

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

742804

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.249

Low

761935

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.249

Low

762088

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

762098

ATG18
Autophagy-related protein 18

1

0

Small-scale

0.249

Low

762101

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.249

Low

762109

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

762112

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

762113

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

762114

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

340145

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

540096

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

640951

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

687384

EF2
Elongation factor 2

1

0

High-throughput

0.232

Low

756921

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.232

Low

760860

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

762091

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.232

Low

762093

IMB4
Importin subunit beta-4

1

0

High-throughput

0.232

Low

762095

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

762099

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

762106

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.232

Low

762108

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024