Protein: SHO1
High osmolarity signaling protein SHO1 (Osmosensor SHO1) (Suppressor of SUA8-1 mutation) (Synthetic high osmolarity-sensitive protein 1)

Gene: SHO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 136
UniProt ID: P40073

Gene Ontology (top 5):
GO:0001402 - signal transduction involved in filamentous growth
GO:0005034 - osmosensor activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

767877

SHO1
High osmolarity signaling protein SHO1

6

0

Small-scale

0.890

High

514629

FUS1
Nuclear fusion protein FUS1

4

0

Small-scale

0.867

High

767919

TUS1
Rho1 guanine nucleotide exchange factor TUS1

2

0

High-throughput

0.775

High

434760

PBS2
MAP kinase kinase PBS2

10

0

Small-scale

0.725

High

687787

MSB2
Signaling mucin MSB2

5

1

Small-scale

0.707

High

767932

LAS17
Proline-rich protein LAS17

4

1

Small-scale

0.703

High

618330

STE11
Serine/threonine-protein kinase STE11

4

0

Small-scale

0.676

High

697935

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.663

High

629730

STE50
Protein STE50

3

0

Small-scale

0.636

High

767922

OPY2
Protein OPY2

3

0

Small-scale

0.636

High

767923

YD073
UPF0592 protein YDL073W

3

0

Small-scale

0.634

High

765838

BOI2
Protein BOI2

1

0

High-throughput

0.622

High

767916

MYO5
Myosin-5

1

0

High-throughput

0.622

High

767906

INN1
Ingression protein 1

2

0

Small-scale

0.616

High

767918

CYK2
Cytokinesis protein 2

2

0

Small-scale

0.616

High

767924

CYK3
Cytokinesis protein 3

2

0

Small-scale

0.616

High

767890

HKR1
Signaling mucin HKR1

2

1

Small-scale

0.601

High

526245

KIN2
Serine/threonine-protein kinase KIN2

2

0

High-throughput

0.594

High

733205

BCH2
Protein BCH2

2

0

High-throughput

0.593

High

761178

RGA1
Rho-type GTPase-activating protein 1

2

0

High-throughput

0.593

High

767914

STE20
Serine/threonine-protein kinase STE20

2

0

Small-scale

0.588

High

452546

KEX1
Pheromone-processing carboxypeptidase KEX1

2

0

High-throughput

0.587

High

667395

CHS3
Chitin synthase 3

2

0

Small-scale

0.587

High

509427

CDC24
Cell division control protein 24

1

0

Small-scale

0.586

High

753624

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

0

High-throughput

0.584

High

767899

LCL3
Probable endonuclease LCL3

2

0

High-throughput

0.577

High

767912

ATN2
Sodium/potassium exporting P-type ATPase 2

1

2

Small-scale

0.568

High

697602

FLO1
Flocculation protein FLO1

1

2

Small-scale

0.552

High

757122

FLO5
Flocculation protein FLO5

1

3

Small-scale

0.552

High

767896

DAN4
Cell wall protein DAN4

1

1

Small-scale

0.552

High

767189

GIP2
GLC7-interacting protein 2

2

1

High-throughput

0.550

High

334706

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

Small-scale

0.543

High

598414

MSB1
Morphogenesis-related protein MSB1

1

0

Small-scale

0.543

High

621168

FPS1
Glycerol uptake/efflux facilitator protein

1

0

Small-scale

0.543

High

767908

PMP3
Plasma membrane proteolipid 3

1

0

Small-scale

0.543

High

767910

SED1
Cell wall protein SED1

1

0

Small-scale

0.543

High

767925

ENT4
Epsin-4

1

0

Small-scale

0.543

High

366366

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.541

High

753264

COS8
Protein COS8

1

2

High-throughput

0.541

High

767902

COS6
Protein COS6

1

2

High-throughput

0.541

High

696506

TOR2
Serine/threonine-protein kinase TOR2

1

0

Small-scale

0.529

High

767915

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

Small-scale

0.529

High

477304

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

Small-scale

0.519

High

541723

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.518

High

556554

ERD1
Protein ERD1

1

0

High-throughput

0.518

High

689430

YBT1
ATP-dependent bile acid permease

1

0

High-throughput

0.518

High

731461

MCH2
Probable transporter MCH2

1

0

High-throughput

0.518

High

756107

YHU0
UPF0641 membrane protein YHR140W

1

0

High-throughput

0.518

High

763552

SEO1
Probable transporter SEO1

1

0

High-throughput

0.518

High

764043

SEC72
Translocation protein SEC72

1

0

High-throughput

0.518

High

767855

TMN3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.518

High

767880

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.518

High

767882

GPI7
GPI ethanolamine phosphate transferase 2

1

0

High-throughput

0.518

High

767921

BSP1
Protein BSP1

1

0

High-throughput

0.518

High

767927

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

0

Small-scale

0.518

High

767930

DGK1
CTP-dependent diacylglycerol kinase 1

1

0

High-throughput

0.518

High

767931

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.518

High

767933

ATN5
Sodium/potassium exporting P-type ATPase 5

1

2

Small-scale

0.515

High

767909

RHO4
GTP-binding protein RHO4

1

1

High-throughput

0.501

High

767893

COS4
Protein COS4

1

2

High-throughput

0.494

High

340152

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.493

High

340685

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.493

High

614970

KC12
Casein kinase I homolog 2

1

0

Small-scale

0.493

High

732466

DCW1
Mannan endo-1,6-alpha-mannosidase DCW1

1

0

Small-scale

0.493

High

516807

SST2
Protein SST2

1

0

Small-scale

0.486

High

623479

KPC1
Protein kinase C-like 1

1

0

High-throughput

0.486

High

690209

CDC3
Cell division control protein 3

1

0

High-throughput

0.486

High

530133

ATN1
Sodium/potassium exporting P-type ATPase 1

1

2

Small-scale

0.481

High

767905

WSC2
Cell wall integrity and stress response component 2

1

1

Small-scale

0.481

High

691059

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.480

High

767886

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.480

High

767887

AIM21
Altered inheritance of mitochondria protein 21

1

0

High-throughput

0.480

High

767911

MDM1
Structural protein MDM1

1

0

High-throughput

0.480

High

767926

NBA1
Protein NBA1

1

0

High-throughput

0.480

High

419702

RHO1
GTP-binding protein RHO1

1

0

Small-scale

0.460

High

474118

GMT2
Probable GDP-mannose transporter 2

1

0

High-throughput

0.460

High

634927

GEX1
Glutathione exchanger 1

1

0

Small-scale

0.460

High

580320

CDC42
Cell division control protein 42

1

0

Small-scale

0.458

High

759189

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

Small-scale

0.458

High

767889

BUD8
Bud site selection protein 8

1

0

Small-scale

0.458

High

767879

PIG2
GSY2-interacting protein PIG2

1

1

High-throughput

0.457

High

543825

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

333805

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

767364

UTP7
U3 small nucleolar RNA-associated protein 7

2

0

High-throughput

0.323

High

761123

PCF11
Protein PCF11

2

0

High-throughput

0.314

High

741389

GLY1
Low specificity L-threonine aldolase

1

0

Small-scale

0.296

High

753215

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

Small-scale

0.296

High

767878

MGDP1
Putative magnesium-dependent phosphatase YER134C

1

0

Small-scale

0.296

High

767891

AAD14
Putative aryl-alcohol dehydrogenase AAD14

1

0

High-throughput

0.296

High

767907

DIA1
Protein DIA1

1

0

Small-scale

0.296

High

767928

HOSM
Homocitrate synthase, mitochondrial

1

0

Small-scale

0.296

High

767929

PUF2
mRNA-binding protein PUF2

1

0

Small-scale

0.296

High

624270

AP2
AP-1-like transcription factor YAP2

1

0

Small-scale

0.288

High

690818

HS150
Cell wall mannoprotein HSP150

1

0

Small-scale

0.288

High

624102

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.282

High

630493

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.282

High

716039

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

0

High-throughput

0.282

High

756157

DSE2
Protein DSE2

1

0

High-throughput

0.282

High

767884

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.282

High

767885

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.282

High

767895

YJ85
Uncharacterized protein YJR115W

1

0

High-throughput

0.282

High

767897

AVT4
Vacuolar amino acid transporter 4

1

0

High-throughput

0.282

High

767898

MCM6
DNA replication licensing factor MCM6

1

0

High-throughput

0.282

High

767901

MTM1
Mitochondrial carrier protein MTM1

1

0

High-throughput

0.282

High

767917

KAR5
Nuclear fusion protein KAR5

1

0

High-throughput

0.282

High

537430

ALF
Fructose-bisphosphate aldolase

1

0

Small-scale

0.269

Low

562240

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

Small-scale

0.269

Low

686889

P5CR
Pyrroline-5-carboxylate reductase

1

0

Small-scale

0.269

Low

686963

GLNA
Glutamine synthetase

1

0

Small-scale

0.269

Low

767883

TPM2
Tropomyosin-2

1

0

Small-scale

0.269

Low

767892

CWP2
Cell wall protein CWP2

1

0

Small-scale

0.269

Low

423684

ADR1
Regulatory protein ADR1

1

0

High-throughput

0.265

Low

577304

GLN3
Nitrogen regulatory protein GLN3

1

0

High-throughput

0.265

Low

605055

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.265

Low

622220

SEC14
SEC14 cytosolic factor

1

0

High-throughput

0.265

Low

690057

ATP11
Protein ATP11, mitochondrial

1

0

High-throughput

0.265

Low

767894

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.265

Low

767900

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.265

Low

767903

THO2
THO complex subunit 2

1

0

High-throughput

0.265

Low

690004

ASF2
Anti-silencing protein 2

1

0

High-throughput

0.261

Low

732201

SRX1
Sulfiredoxin

1

0

High-throughput

0.261

Low

767888

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.261

Low

767904

YN93
Uncharacterized hydrolase YNR064C

1

0

High-throughput

0.261

Low

767920

SUE1
Protein SUE1, mitochondrial

1

0

High-throughput

0.261

Low

667361

PTP2
Tyrosine-protein phosphatase 2

1

0

Small-scale

0.251

Low

763745

BOL3
BolA-like protein 3

1

0

Small-scale

0.251

Low

767881

ATAD2
ATPase histone chaperone YTA7

1

0

Small-scale

0.251

Low

767934

YH048
Uncharacterized protein YHL048C-A

1

0

Small-scale

0.251

Low

767935

YL154
Uncharacterized protein YLR154C-G

1

0

Small-scale

0.251

Low

662352

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

767913

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.249

Low

368105

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

411013

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.232

Low

520839

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.232

Low

560984

EF3A
Elongation factor 3A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024