Protein: ILV5
Ketol-acid reductoisomerase, mitochondrial (EC 1.1.1.86) (Acetohydroxy-acid reductoisomerase) (Alpha-keto-beta-hydroxylacyl reductoisomerase) (Isoleucine-plus-valine requiring protein 5)

Gene: ILV5
Organism: Saccharomyces cerevisiae S288C
Interactions: 135
UniProt ID: P06168

Gene Ontology (top 5):
GO:0000002 - mitochondrial genome maintenance
GO:0003690 - double-stranded DNA binding
GO:0004455 - ketol-acid reductoisomerase activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

410723

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

2

High-throughput

0.618

High

410744

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

410773

HS104
Heat shock protein 104

2

1

Small-scale

0.584

High

410763

SIS1
Protein SIS1

2

0

High-throughput

0.576

High

365550

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.571

High

410738

HSP77
Import motor subunit, mitochondrial

2

0

High-throughput

0.559

High

410749

MDHM
Malate dehydrogenase, mitochondrial

2

0

Small-scale

0.559

High

410794

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

2

0

Small-scale

0.559

High

410814

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

410726

SIR3
Regulatory protein SIR3

1

1

High-throughput

0.536

High

410825

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

410742

AROF
Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited

1

0

High-throughput

0.513

High

410762

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.513

High

410783

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

0

High-throughput

0.513

High

410805

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.513

High

410824

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.513

High

343063

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.493

High

410724

KAPB
cAMP-dependent protein kinase type 2

1

0

High-throughput

0.479

High

410741

EI2BD
Translation initiation factor eIF2B subunit delta

1

0

High-throughput

0.479

High

410752

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.479

High

410755

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.479

High

410764

MSH3
DNA mismatch repair protein MSH3

1

0

High-throughput

0.479

High

410774

CDC3
Cell division control protein 3

1

0

High-throughput

0.479

High

410776

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.479

High

410791

IMB2
Importin subunit beta-2

1

0

High-throughput

0.479

High

410800

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.479

High

410820

RHO5
GTP-binding protein RHO5

1

0

High-throughput

0.479

High

410841

ATG5
Autophagy protein 5

1

0

High-throughput

0.479

High

410844

AP2M
AP-2 complex subunit mu

1

0

High-throughput

0.479

High

341865

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.479

High

410728

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

410729

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.479

High

410751

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

410757

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

410771

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

410772

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

410781

YPT7
Ypt/Rab-type GTPase YPT7

1

1

Small-scale

0.479

High

410784

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

410823

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

410834

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

1

Small-scale

0.479

High

334400

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.458

High

342810

ENO2
Enolase 2

1

0

High-throughput

0.458

High

345257

STF1
F(1)-ATPase inhibitor STF1, mitochondrial

1

0

High-throughput

0.458

High

367513

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

389184

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

389804

VDAC1
Mitochondrial outer membrane protein porin 1

1

0

High-throughput

0.458

High

404279

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.458

High

405321

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

406642

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

410725

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

410727

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

410730

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

410731

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

410732

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

410734

FUMH
Fumarate hydratase, mitochondrial

1

0

High-throughput

0.458

High

410735

ATPO
ATP synthase subunit 5, mitochondrial

1

0

High-throughput

0.458

High

410736

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

410737

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

410739

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

410740

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

410745

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

410750

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

410754

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.458

High

410758

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

410759

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

410760

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

410761

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

410765

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

410767

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.458

High

410769

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

0

High-throughput

0.458

High

410770

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

0

High-throughput

0.458

High

410775

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

410778

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

410779

PREP
Presequence protease, mitochondrial

1

0

High-throughput

0.458

High

410785

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

410786

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

410788

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.458

High

410790

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

0

High-throughput

0.458

High

410792

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

410802

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

410803

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

410806

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

0

High-throughput

0.458

High

410808

MMF1
Protein MMF1, mitochondrial

1

0

High-throughput

0.458

High

410810

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

410812

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

410813

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

410817

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

410818

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

410819

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

410822

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

410826

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

410837

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

410839

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

410804

ACON2
Homocitrate dehydratase, mitochondrial

1

1

High-throughput

0.445

High

410830

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

410842

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

410807

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

410809

DJP1
DnaJ-like protein 1

1

0

High-throughput

0.426

High

410821

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

410756

NUP1
Nucleoporin NUP1

1

0

High-throughput

0.279

Low

410787

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

410795

SPT8
Transcription factor SPT8

1

0

High-throughput

0.279

Low

410831

LCD1
DNA damage checkpoint protein LCD1

1

0

High-throughput

0.279

Low

410733

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.261

Low

410743

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.261

Low

410748

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.261

Low

410753

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.261

Low

410777

CDC13
Cell division control protein 13

1

0

High-throughput

0.261

Low

410780

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

410797

DUN1
DNA damage response protein kinase DUN1

1

0

High-throughput

0.261

Low

410798

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.261

Low

410811

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.261

Low

410840

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.261

Low

410766

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.249

Low

410768

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

410782

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

410789

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

410793

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

410796

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

410801

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.249

Low

410816

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

410827

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.249

Low

410828

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.249

Low

410829

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

Small-scale

0.249

Low

410832

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

410833

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

410835

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

410836

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

410746

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.232

Low

410747

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.232

Low

410799

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

410815

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

410838

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.232

Low

410843

H2AZ
Histone H2A.Z

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024