Protein: IMB1
Importin subunit beta-1 (Importin-95) (Karyopherin subunit beta-1) (Karyopherin-95)

Gene: IMB1, KAP95
Organism: Saccharomyces cerevisiae S288C
Interactions: 213
UniProt ID: Q06142

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

972912

IMA1
Importin subunit alpha

22

20

Small-scale

0.991

High

698945

GSP1
GTP-binding nuclear protein GSP1/CNR1

19

17

Small-scale

0.987

High

688003

IMB3
Importin subunit beta-3

4

12

Small-scale

0.892

High

392205

H2A1
Histone H2A.1

3

5

Small-scale

0.840

High

595074

NUP1
Nucleoporin NUP1

25

20

Small-scale

0.768

High

763526

NUP60
Nucleoporin NUP60

14

2

Small-scale

0.762

High

691667

NUP2
Nucleoporin NUP2

14

20

Small-scale

0.761

High

971878

NU100
Nucleoporin NUP100/NSP100

13

20

Small-scale

0.760

High

971907

NU116
Nucleoporin NUP116/NSP116

11

20

Small-scale

0.756

High

541927

NSP1
Nucleoporin NSP1

7

20

Small-scale

0.744

High

972014

ULP1
Ubiquitin-like-specific protease 1

7

6

Small-scale

0.743

High

986154

RRP6
Exosome complex exonuclease RRP6

7

2

Small-scale

0.739

High

830656

NUP42
Nucleoporin NUP42

6

20

Small-scale

0.727

High

986150

NCBP2
Nuclear cap-binding protein subunit 2

6

4

High-throughput

0.727

High

969363

NUP49
Nucleoporin NUP49/NSP49

5

20

Small-scale

0.713

High

607343

RFA1
Replication factor A protein 1

5

7

Small-scale

0.712

High

823006

NUP57
Nucleoporin NUP57

5

20

Small-scale

0.707

High

774378

NU159
Nucleoporin NUP159

4

20

Small-scale

0.686

High

830681

NU145
Nucleoporin NUP145

4

20

Small-scale

0.683

High

710222

NCBP1
Nuclear cap-binding protein complex subunit 1

4

1

High-throughput

0.678

High

983343

NUP59
Nucleoporin ASM4

3

4

Small-scale

0.670

High

986140

IMB1
Importin subunit beta-1

1

10

High-throughput

0.665

High

606146

RAD53
Serine/threonine-protein kinase RAD53

3

3

High-throughput

0.657

High

977644

NUP53
Nucleoporin NUP53

3

4

Small-scale

0.651

High

544439

HSC82
ATP-dependent molecular chaperone HSC82

3

7

High-throughput

0.633

High

693162

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

2

1

Small-scale

0.628

High

747256

SIF2
SIR4-interacting protein SIF2

2

5

High-throughput

0.621

High

837559

ZDS1
Protein ZDS1

2

2

High-throughput

0.621

High

355646

H2B1
Histone H2B.1

1

6

Small-scale

0.618

High

676383

XPO1
Exportin-1

1

7

High-throughput

0.618

High

730921

CENPA
Histone H3-like centromeric protein CSE4

1

14

High-throughput

0.618

High

746545

IMB2
Importin subunit beta-2

1

12

High-throughput

0.618

High

797950

RSC8
Chromatin structure-remodeling complex protein RSC8

2

3

High-throughput

0.612

High

862767

THO2
THO complex subunit 2

2

1

High-throughput

0.612

High

767738

IMB4
Importin subunit beta-4

2

11

High-throughput

0.611

High

512784

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.601

High

733308

SET3
SET domain-containing protein 3

2

2

High-throughput

0.601

High

986163

RLF2
Chromatin assembly factor 1 subunit p90

2

1

High-throughput

0.601

High

527063

TBP
TATA-box-binding protein

2

1

Small-scale

0.595

High

857046

NUP84
Nucleoporin NUP84

2

2

Small-scale

0.595

High

866012

EAF7
Chromatin modification-related protein EAF7

2

1

Small-scale

0.588

High

860886

PESC
Pescadillo homolog

2

0

High-throughput

0.585

High

774000

MLP2
Protein MLP2

2

9

Small-scale

0.584

High

986169

MEX67
mRNA export factor MEX67

2

6

High-throughput

0.584

High

587885

AP1
AP-1-like transcription factor YAP1

2

2

Small-scale

0.576

High

977611

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

2

0

High-throughput

0.576

High

492478

HSP71
Heat shock protein SSA1

2

9

Small-scale

0.571

High

707936

GCN1
eIF-2-alpha kinase activator GCN1

2

9

High-throughput

0.571

High

785220

MPG1
Mannose-1-phosphate guanyltransferase

2

2

High-throughput

0.562

High

858489

MIG2
Regulatory protein MIG2

1

20

Small-scale

0.561

High

494994

HSP72
Heat shock protein SSA2

2

9

High-throughput

0.552

High

769512

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

730764

NDK
Nucleoside diphosphate kinase

1

2

High-throughput

0.541

High

389416

HXKB
Hexokinase-2

1

0

Small-scale

0.537

High

986146

RRP44
Exosome complex exonuclease DIS3

1

0

Small-scale

0.537

High

424717

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.536

High

498597

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.536

High

583261

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.536

High

695556

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.536

High

741490

CCL1
Cyclin CCL1

1

3

High-throughput

0.536

High

791153

LEM3
Phospholipid-transporting ATPase accessory subunit LEM3

1

1

High-throughput

0.536

High

804850

RSSA2
Small ribosomal subunit protein uS2B

1

3

High-throughput

0.536

High

986149

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

3

High-throughput

0.536

High

448223

F16P
Fructose-1,6-bisphosphatase

1

0

High-throughput

0.518

High

705958

SPC29
Spindle pole component 29

1

0

High-throughput

0.518

High

416251

SIR2
NAD-dependent histone deacetylase SIR2

1

7

Small-scale

0.515

High

628485

SIS1
Protein SIS1

1

2

High-throughput

0.515

High

688726

AAR2
A1 cistron-splicing factor AAR2

1

3

High-throughput

0.515

High

755377

YNG2
Chromatin modification-related protein YNG2

1

2

High-throughput

0.515

High

758818

IPL1
Spindle assembly checkpoint kinase

1

3

High-throughput

0.515

High

965010

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

1

High-throughput

0.515

High

984164

RT103
Regulator of Ty1 transposition protein 103

1

1

High-throughput

0.515

High

986147

SGT1
Protein SGT1

1

1

High-throughput

0.515

High

986161

NOP56
Nucleolar protein 56

1

2

High-throughput

0.515

High

579817

SNF6
Transcription regulatory protein SNF6

1

0

High-throughput

0.513

High

770175

PIG2
GSY2-interacting protein PIG2

1

0

High-throughput

0.513

High

865203

POP3
Ribonucleases P/MRP protein subunit POP3

1

0

High-throughput

0.513

High

986157

RLM1
Transcription factor RLM1

1

0

High-throughput

0.513

High

709353

NIC96
Nucleoporin NIC96

1

4

Small-scale

0.501

High

761926

RS14B
Small ribosomal subunit protein uS11B

1

3

Small-scale

0.501

High

858405

SEH1
Nucleoporin SEH1

1

7

Small-scale

0.501

High

986142

ASR1
Alcohol-sensitive RING finger protein 1

1

2

Small-scale

0.501

High

986155

POM33
Pore membrane protein of 33 kDa

1

3

Small-scale

0.501

High

986158

GLE1
mRNA export factor GLE1

1

2

Small-scale

0.501

High

404376

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.493

High

479534

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.493

High

586337

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

High-throughput

0.493

High

811800

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.493

High

832201

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.493

High

858883

TAN1
tRNA acetyltransferase TAN1

1

0

High-throughput

0.493

High

862502

OGG1
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase

1

0

High-throughput

0.493

High

985132

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.493

High

691718

NDC1
Nucleoporin NDC1

1

0

Small-scale

0.480

High

986159

POM34
Nucleoporin POM34

1

0

Small-scale

0.480

High

366915

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

406409

RL15A
Large ribosomal subunit protein eL15A

1

2

Small-scale

0.479

High

477453

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

10

High-throughput

0.479

High

477650

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

7

High-throughput

0.479

High

481703

RL18B
Large ribosomal subunit protein eL18B

1

2

Small-scale

0.479

High

485830

IF4A
ATP-dependent RNA helicase eIF4A

1

4

High-throughput

0.479

High

499083

RL4A
Large ribosomal subunit protein uL4A

1

4

Small-scale

0.479

High

503141

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.479

High

515015

RNA1
Ran GTPase-activating protein 1

1

4

High-throughput

0.479

High

593410

CG12
G1/S-specific cyclin CLN2

1

2

Small-scale

0.479

High

599517

VPS1
Vacuolar protein sorting-associated protein 1

1

3

High-throughput

0.479

High

602763

MCK1
Protein kinase MCK1

1

6

High-throughput

0.479

High

645137

RL16A
Large ribosomal subunit protein uL13A

1

1

Small-scale

0.479

High

645277

RL16B
Large ribosomal subunit protein uL13B

1

1

Small-scale

0.479

High

663356

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

681000

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

688430

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

692084

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

2

High-throughput

0.479

High

701091

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

731080

YKT6
Synaptobrevin homolog YKT6

1

3

High-throughput

0.479

High

733719

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

1

High-throughput

0.479

High

745894

NU170
Nucleoporin NUP170

1

4

Small-scale

0.479

High

754073

BRL1
Nucleus export protein BRL1

1

1

Small-scale

0.479

High

755544

GGA2
ADP-ribosylation factor-binding protein GGA2

1

1

High-throughput

0.479

High

755804

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

5

Small-scale

0.479

High

762023

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

762572

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

766408

GEA2
ARF guanine-nucleotide exchange factor 2

1

3

High-throughput

0.479

High

774317

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

1

High-throughput

0.479

High

785008

YRB1
Ran-specific GTPase-activating protein 1

1

20

High-throughput

0.479

High

829701

RL4B
Large ribosomal subunit protein uL4B

1

4

Small-scale

0.479

High

837426

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.479

High

872757

RL15B
Large ribosomal subunit protein eL15B

1

2

Small-scale

0.479

High

970963

MLP1
Protein MLP1

1

8

High-throughput

0.479

High

975833

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

978003

RUVB1
RuvB-like protein 1

1

5

High-throughput

0.479

High

978615

SXM1
Importin beta SMX1

1

8

High-throughput

0.479

High

986141

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

986143

BRE1
E3 ubiquitin-protein ligase BRE1

1

4

Small-scale

0.479

High

986148

ESA1
Histone acetyltransferase ESA1

1

4

Small-scale

0.479

High

986153

ELG1
Telomere length regulation protein ELG1

1

1

Small-scale

0.479

High

986156

RIO1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

986160

OSH2
Oxysterol-binding protein homolog 2

1

1

High-throughput

0.479

High

986167

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.479

High

986164

NOP58
Nucleolar protein 58

1

2

High-throughput

0.470

High

482996

RS32B
Small ribosomal subunit protein eS32B

1

0

Small-scale

0.458

High

581379

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

High-throughput

0.458

High

696670

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.458

High

704426

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

716360

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

716508

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

746229

SHE1
Mitotic spindle-associated protein SHE1

1

0

High-throughput

0.458

High

766959

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

0

High-throughput

0.458

High

767571

RT105
Regulator of Ty1 transposition protein 105

1

0

Small-scale

0.458

High

805129

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.458

High

810857

TIM54
Mitochondrial import inner membrane translocase subunit TIM54

1

0

High-throughput

0.458

High

811770

RAV1
Regulator of V-ATPase in vacuolar membrane protein 1

1

0

High-throughput

0.458

High

864467

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.458

High

866480

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

960471

NAM8
Protein NAM8

1

0

High-throughput

0.458

High

962002

REG1
Resistance to glucose repression protein 1

1

0

Small-scale

0.458

High

972635

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

978534

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.458

High

983794

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

986168

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.458

High

334817

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

High-throughput

0.445

High

361035

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

368418

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

650390

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.445

High

689965

ASF1
Histone chaperone ASF1

1

3

High-throughput

0.445

High

692622

ZUO1
Zuotin

1

3

High-throughput

0.445

High

705672

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

746602

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.445

High

811354

NOP9
Nucleolar protein 9

1

1

High-throughput

0.445

High

864162

HST3
NAD-dependent histone deacetylase HST3

1

7

High-throughput

0.445

High

960599

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

2

High-throughput

0.445

High

981155

RCO1
Transcriptional regulatory protein RCO1

1

13

High-throughput

0.445

High

986166

SET6
Potential protein lysine methyltransferase SET6

1

1

High-throughput

0.445

High

542697

TAL1
Transaldolase

1

0

High-throughput

0.438

High

495879

CP51
Lanosterol 14-alpha demethylase CYP51

1

1

High-throughput

0.437

High

605876

SEC22
Protein transport protein SEC22

1

3

High-throughput

0.437

High

638859

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

644777

RFA2
Replication factor A protein 2

1

6

Small-scale

0.437

High

688051

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

4

High-throughput

0.437

High

688622

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

1

High-throughput

0.437

High

690798

ERG1
Squalene epoxidase ERG1

1

2

High-throughput

0.437

High

704646

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

4

High-throughput

0.437

High

771652

ELO3
Fatty acid elongase 3

1

3

High-throughput

0.437

High

822930

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

972445

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

3

High-throughput

0.437

High

986145

COQ10
Coenzyme Q-binding protein COQ10, mitochondrial

1

1

High-throughput

0.437

High

986151

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

526629

PCY1
Choline-phosphate cytidylyltransferase

1

0

High-throughput

0.426

High

761317

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

763722

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.426

High

960008

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

978559

YHP1
Homeobox protein YHP1

1

0

High-throughput

0.426

High

986165

RKM4
Ribosomal lysine N-methyltransferase 4

1

0

High-throughput

0.426

High

659193

LAC1
Ceramide synthase LAC1

1

5

High-throughput

0.407

High

752779

LAG1
Ceramide synthase LAG1

1

5

High-throughput

0.407

High

759040

HXT7
High-affinity hexose transporter HXT7

1

2

High-throughput

0.407

High

810643

GWT1
GPI-anchored wall transfer protein 1

1

1

High-throughput

0.407

High

978671

PDR15
ATP-dependent permease PDR15

1

2

High-throughput

0.407

High

986162

AIR2
Protein AIR2

1

1

High-throughput

0.407

High

980193

SSL1
General transcription and DNA repair factor IIH subunit SSL1

2

0

High-throughput

0.307

High

500630

TIR1
Cold shock-induced protein TIR1

2

0

Small-scale

0.305

High

744542

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

High-throughput

0.282

High

644827

RFA3
Replication factor A protein 3

1

0

High-throughput

0.279

Low

986144

NOP6
Nucleolar protein 6

1

0

High-throughput

0.279

Low

410182

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.269

Low

755330

RPF1
Ribosome production factor 1

1

0

Small-scale

0.261

Low

634299

MGR1
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1

1

0

High-throughput

0.249

Low

746662

CST26
2-acyl-1-lysophosphatidylinositol acyltransferase

1

0

High-throughput

0.249

Low

758471

RRP8
25S rRNA

1

0

High-throughput

0.249

Low

772465

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.249

Low

864528

YN8O
Uncharacterized protein YNR040W

1

0

High-throughput

0.249

Low

986152

TGL5
Triacylglycerol lipase 5

1

0

High-throughput

0.249

Low

761083

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024